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Technique for Rapidly Reprogramming Adult Cells Into Stem Cells Published in PLoS Biology
Date:10/24/2008

lly improved; partly converted stem cells complete the transition efficiently and become indistinguishable from authentic embryonic stem (ES) cells (i.e. those generated from early stage embryos).

The combination of chemical inhibitors used in this technique also forms the basis for SCS' Culticell iSTEM(TM) media range, which is being bought and used by researchers to establish pure and stable populations of authentic ES cells. SCS' Culticell iSTEM(TM) medium was launched earlier this year and is part of SCS' stem cell culture media business, which provides a growing and important revenue source for the company.

Dr Tim Allsopp, Chief Scientific Officer of Stem Cell Sciences, commented, "This proprietary technique greatly facilitates the simple, most reliable and efficient route to obtaining authentic induced pluripotent stem cells and will form the basis for the industrialization of iPS cell production. This peer-reviewed publication is an important validation of the technology Professor Smith and his team have developed and Stem Cell Sciences is very pleased to be working with Cambridge University and Professor Smith's team on this important breakthrough."

(1) Promotion of Reprogramming to Ground State Pluripotency by Signal

Induction. Silva, J. et al. (2008) PLoS Biol 6(10): e253

doi:10.1371/journal.pbio.0060253

About Stem Cell Sciences plc

Stem Cell Sciences (SCS) is an international research and development company focusing on the commercial application of stem cell biology technologies for drug discovery and regenerative medicine research. Stem Cell Sciences is now focusing on building revenues through the sale of products, collaborative research and licensing deals with international biotechnology and pharmaceutical companies.

Stem Cell Sciences has a substantial portfolio of patents and patent applications in both adult and embryonic stem cell fields. The Company has been active in the stem c
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SOURCE Stem Cell Sciences plc
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