Tarix Pharmaceuticals' Peptide Technology Stimulates Revascularization Followin... (there was a substantial increase in cere...)

Tarix Pharmaceuticals' Peptide Technology Stimulates Revascularization Following Ischemia

Date:3/5/2013

there was a substantial increase in cerebral blood flow and histologic evidence of new blood vessel formation.

Separately, in a mouse model of unilateral hindlimb ischemia, ischemic recovery was compared between TXA127 or PanCyte treatment versus control animals. Blood flow in treated animals improved significantly faster toward normal, with percent blood flow more than double that of control animals by day 49 (~85% vs ~40%). Histologic examination again showed a significant increase in the number of functional blood vessels amongst treated animals compared to controls.

About Tarix Pharmaceuticals
Tarix Pharmaceuticals is a biopharmaceutical company focused on developing novel, peptide-based therapies to treat a range of critical medical conditions. Tarix' proprietary technology platform consists of TXA127, a pharmaceutical formulation of the naturally occurring peptide, Angiotensin (1-7), and PanCyte, a cyclic analogue of TXA127 with an extended half-life. TXA127 and PanCyte have shown striking effects in models of ischemic stroke and peripheral vascular disease through improvement in endothelial progenitor cell number and function. The peptides have also been effective in models of diabetes. Tarix intends to initiate clinical trials in these indications during 2013, adding to its clinical pipeline that includes multiple programs in hematopoiesis.For Tarix Pharmaceuticals:

Media / Investor Contacts:Rick Franklin

Jason Rando / Claire Sojda Rick.franklin@tarixpharma.com

Tiberend Strategic Advisors, Inc.212.827.0020jrando@tiberend.com csojda@tiberend.com

SOURCE Tarix Pharmaceuticals
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