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Takeda presenta la richiesta di autorizzazione all'immissione in commercio nell'Unione Europea per Vedolizumab nella colite ulcerosa moderata-grave e nella malattia di Crohn
Date:3/8/2013

rattamenti per le MICI sono l'induzione e il mantenimento dello stato di remissione della malattia, ovvero il conseguimento di periodi asintomatici prolungati.

Vedolizumab

Il vedolizumab, sviluppato per il trattamento del MC e della CU, è un anticorpo monoclonale umanizzato a selettività intestinale, che antagonizza specificamente l'integrina alfa-4-beta-7 (α4β7), espressa in un sottogruppo di leucociti circolanti. Queste cellule hanno dimostrato di avere un ruolo nella mediazione del processo infiammatorio durante la MC e la CU. L'α4β7 si lega a una specifica molecola d'adesione, principalmente espressa nel tratto intestinale. Il vedolizumab, pertanto, impedendo questa interazione, sviluppa un effetto selettivo intestinale.

Takeda Pharmaceutical Company Limited
Con sede a Osaka, in Giappone, Takeda è un'azienda globale impegnata nel settore della ricerca specializzata nei prodotti farmaceutici. In qualità di più grande azienda farmaceutica giapponese e leader mondiale del settore, Takeda è impegnata a migliorare le condizioni di salute dei pazienti di tutto il mondo attraverso l'innovazione in campo medico. Per maggiori informazioni su Takeda, visitare il sito web: http://www.takeda.com

Questo comunicato stampa contiene dichiarazioni previsionali. Le dichiarazioni previsionali sono dichiarazioni riguardanti piani, prospettive, strategie e risultati futuri di Takeda , oltre a contenere altre affermazioni non riguardanti dati storici. Le dichiarazioni previsionali possono essere contraddistinte dall'uso di termini previsionali come "potere", "ritenere", "sarà", "aspettarsi", "progettare", "stimare", "dovrebbe", "anticipare", "pianificare","supporre","continuare","cercare","pro-forma","potenziale","target","previsione","guida","prospettiva","intenzione" o da a
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