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Takeda Completes Settlements With All Defendants in U.S. Patent Litigation Involving ACTOS® (pioglitazone HCI), ACTOplus met® (pioglitazone HCl and metformin HCl) and duetact® (pioglitazone HCl and glimepiride)
Date:12/21/2010

fractures while taking ACTOS, ACTOplus met, ACTOplus met XR, or duetact.

Precaution Specific to duetact: Taking glimepiride along with having an inherited condition where a patient doesn't produce enough of the enzyme G6PD (G6PD deficiency) can cause hemolytic anemia, which causes red blood cells to be destroyed too quickly.

Other side effects of these products may include:

  • ACTOS: cold or flu-like symptoms, headache, sinus infection, muscle pain, tooth disorder, and sore throat
  • ACTOplus met and ACTOplus met XR: cold or flu-like symptoms, diarrhea, nausea, headache, urinary tract infection, dizziness, and sinus infection
  • Duetact: cold or flu-like symptoms, headache, urinary tract infection, diarrhea, nausea, and limb pain

Patients are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

For ACTOS Complete Prescribing Information, including warning about heart failure, and Medication Guide, please click here.

For ACTOplus met and ACTOplus met XR Complete Prescribing Information, including warnings about heart failure, and lactic acidosis, and Medication Guide, please click here.

For duetact Complete Prescribing Information, including warning about heart failure, and Medication Guide, please click

SOURCE Takeda Pharmaceuticals North America, Inc.
Copyright©2010 PR Newswire.
All rights reserved

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