Navigation Links
Taiho Pharmaceutical présente une demande d'homologation pour la fabrication et la commercialisation du nouvel agent antitumoral TAS-102
Date:2/26/2013

TOKYO, 27 février 2013 /PRNewswire/ -- Taiho Pharmaceutical Co., Ltd. a annoncé le 27 février avoir présenté le 26 février une demande d'homologation pour la fabrication et la commercialisation du nouvel agent antitumoral nucléoside administré par voie orale, le TAS-102 (mélange de Trifluorothymidine [FTD] et de tipiracil hydrochloride[TPI]), auprès du Ministère japonais de la Santé publique et du Travail. Taiho Pharmaceutical cherche à obtenir l'homologation pour le TAS-102 de l'indication contre le cancer colorectal récurrent à un stade avancé, non résécable.

La demande d'homologation se base sur les résultats de l'essai clinique de phase II (Étude 10040030) effectué dans 20 centres médicaux au Japon. C'est un essai à répartition aléatoire, mené en double insu pour comparer le TAS-102 à un placébo. Il porte sur 172 patients souffrant de cancer colorectal récurrent à un stade avancé, non résécable et réfractaire aux chimiothérapies standard d'au moins deux régimes contenant un mélange de fluoropyrimidine, d'irinotécan et d'oxaliplatine. Selon les résultats, le groupe à qui le TAS-102 a été administré a vu son taux de survie s'améliorer (durée médiane de survie globale : 9 mois contre 6,6 mois) et le risque de mortalité significativement réduire (HR : 0.56, p=0.0011). L'effet secondaire au médicament CTCAE de niveau 3 ou plus le plus fréquemment rapporté est la neutropénie. La diarrhée, la fatigue, la nausée et autres effets secondaires de niveau 3 n'ont pas dépassé les 10 %. Taiho Pharmaceutical mène actuellement un essai clinique mondial de phase III portant sur le TAS-102 sur une population similaire souffrant d'un cancer colorectal (RECOURSE
'/>"/>

SOURCE Taiho Pharmaceutical Co., Ltd.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Taiho Pharmaceutical Announces Start of Global Phase III Clinical Trial in Metastatic Colorectal Cancer with Novel Antitumor Agent TAS-102
2. Jazz Pharmaceuticals Reports Full Year And Fourth Quarter 2012 Financial Results
3. Cadence Pharmaceuticals CEO Ted Schroeder To Present At The Cowen & Company 33rd Annual Health Care Conference In Boston On March 5, 2013
4. Global Pharmaceutical Industry Trends: Procurement Budgets Stay the Same, Marketing Budgets to Experience Slight Decrease
5. Savient Pharmaceuticals to Hold Fourth Quarter and Year-End 2012 Financial Results Conference Call on Tuesday, March 19, 2013
6. Savara Pharmaceuticals Announces Formation of Clinical Advisory Board
7. Isis Pharmaceuticals Initiates Phase 2 Study Of ISIS-CRP Rx In Patients With Atrial Fibrillation
8. UBM Launches PharmaEvolution.com, an Online Peer-to-Peer Network for Pharmaceutical Industry Professionals
9. Alexza Pharmaceuticals Corporate Presentation to Be Webcast at Three Upcoming Investor Conferences
10. Arena Pharmaceuticals to Host Corporate Update and Financial Results Conference Call and Webcast on Monday, March 4
11. DelMar Pharmaceuticals Announces $1.6 Million Closing in Private Placement
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... DIEGO , Oct. 21, 2014   ... today the latest genomics research centers to purchase ... Salk Institute, the National Cancer Institute (NCI), NIH ... Sequencing Center). Before Irys, obtaining a comprehensive view ... next generation sequencing (NGS) does not deliver the ...
(Date:10/22/2014)... , Oct. 21, 2014 Influenza will affect ... deaths in the United States as ... are thought to spread is from person to person in ... has a serve way of death, but kills much fewer ... is also done by human fluids including sweat, saliva, blood ...
(Date:10/22/2014)... NEW YORK , Oct. 22, 2014 ... an August 2014 report by Global Research & Data ... 6.2% per year from 2014 through 2018, as demand ... United States is the world,s largest market ... market with advanced thermometers is Sanomedics International Holdings, Inc. ...
Breaking Medicine Technology:BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 2BioNano's Irys System Adopted by Leading Genomics Centers for Comprehensive Detection of Human Genome Structural Variation 3WholeHealth Products is proud to be releasing its Influenza A and B combo test, on the heels of the announcing of its phase 2 completion of the Rapid Ebola Test 2Sanomedics International Holdings Analyst Report: Taking Some Heat by BrokerBank Securities, Inc. 2
... CORDOVA, Calif., Jan. 23, 2012 ThermoGenesis Corp. (NASDAQ: ... services that process and store adult stem cells, said today, ... System from a new public cord blood bank that ... Canadian Blood Services, a national charitable organization that manages the ...
... (OTC.BB: SPIN.PK), a rapidly growing medical, management, billing and collection ... To Appear at Investor Conference January 23, ... with investors at the Southern California Investment Forum on January ... The Southern California Investment Forum is ...
Cached Medicine Technology:Canada's First National Public Cord Blood Bank Adopts ThermoGenesis BioArchive Cryopreservation System 2Canada's First National Public Cord Blood Bank Adopts ThermoGenesis BioArchive Cryopreservation System 3Canada's First National Public Cord Blood Bank Adopts ThermoGenesis BioArchive Cryopreservation System 4Spine Pain Management, Inc. Provides Corporate Updates 2
(Date:10/22/2014)... For Dr. Iris Hunter, a job is ... extension of her life’s mission. Her extensive experience in the ... of FirstLight HomeCare, make it clear that Hunter’s mission is ... my work makes a difference in the lives of others,” ... after much research, I felt ready to start on this ...
(Date:10/22/2014)... Angeles, California (PRWEB) October 22, 2014 Hay ... 2.0: Move Beyond Addiction and Upgrade Your Life (Paperback; $10.82) ... field of Yoga & Recovery. This book is meant ... thrive in a life of recovery. , Recovery 2.0 ... the 12 Steps; Recovery 2.0 is a guide for what ...
(Date:10/22/2014)... Losing Weight Your Body’s Way , In a ... the face, it certainly can be difficult to choose the ... extra favor by doing it the healthy way? Set aside ... to your body, exercise regularly, and choose foods with the ... weight; you need to exercise more and eat less. Despite ...
(Date:10/22/2014)... HealthDay Reporter , TUESDAY, Oct. 21, 2014 (HealthDay ... be showing a genetic propensity for obesity as toddlers, a ... linked to increased body fat, but the same genes in ... researchers said. At 1 year, kids with these genes ... however, these genes were linked to excessive weight gain, the ...
(Date:10/22/2014)... -- Measures taken by Firestone officials at the company,s ... limited the spread of the disease there and could ... Rubber Co. provides health services to about 80,000 employees, ... communities. Between Aug. 1 and Sept. 23, there ... 80,000 people. That incidence rate of 0.09 percent was ...
Breaking Medicine News(10 mins):Health News:Dr. Iris Hunter to Host Grand Opening of FirstLight HomeCare Tomorrow 2Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 2Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 3Health News:ReductionGuruMD Presents Ways to Improve Your Weight Loss Results 2Health News:Tall, Heavy 1-Year-Olds May Be at Risk for Obesity Later, Study Finds 2Health News:Tire Company Sets Standard for Ebola Care in Liberia: CDC 2
... By Jenifer Goodwin HealthDay Reporter , ... eight genes in the development of alopecia areata, a ... The genes are already associated with other autoimmune ... that drugs may already be in the pipeline that ...
... By Jenifer Goodwin HealthDay Reporter , WEDNESDAY, ... disease patients who received fetal cell transplants in the ... can prevent the troublesome side effect. The findings ... said. "These findings lend much optimism to new ...
... ... Unveils Military-Inspired Website on July 2nd to Expand Support of US Armed Forces and ... ... in performance apparel, footwear and accessories today announced the July 2nd launch of UA ...
... , WEDNESDAY, June 30 (HealthDay News) -- If you want to ... a new study suggests it might be a good idea to ... a link between exercise in adolescence and fewer cases of senility ... that exercise lowers the risk of dementia. And the research is ...
... (APS) ( www.aps.org ), a leading organization of ... Regulatory Commission (NRC) requesting the agency change its ... proliferation risks associated with smaller, more efficient nuclear ... the secret development of nuclear weapons, including incidents ...
... Researchers have identified a set of "molecular signatures" for ... liver transplant in children that can help identify ... outcomes. The Cincinnati Children,s Hospital Medical Center scientists ... only 14 of 47 infants with biliary atresia could ...
Cached Medicine News:Health News:Genes Tied to Hair Loss Disorder 2Health News:Genes Tied to Hair Loss Disorder 3Health News: Parkinson's Transplant Mystery Solved, Researchers Say 2Health News: Parkinson's Transplant Mystery Solved, Researchers Say 3Health News:Under Armour Launches UA Freedom Initiative in Celebration of Independence Day 2Health News:Under Armour Launches UA Freedom Initiative in Celebration of Independence Day 3Health News:Exercise May Guard Girls Against Dementia in Senior Years 2Health News:APS Physics files petition requesting NRC change licensing rules 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: