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TYRX Presents Early Clinical Results from AIGISRX(TM) Antibacterial Envelope Retrospective Registry
Date:5/14/2009

PM ICD/CRT infection infection Implant Type implants infections rate implants infections rate De novo 15 0 0.0% 51 0 0.0% Revision 38 0 0.0% 141 1 0.4% Total 53 0 0.0% 192 1 0.4% Other Total infection infection Implant Type implants infections rate implants infections rate De novo 1 0 0.0% 67 0 0.0% Revision 8 0 0.0% 187 1 0.4% Total 9 0 0.0% 254 1 0.4%

Dr. Dan Lerner, TYRX's Chief Medical Officer, noted that "when one looks at the characteristics of the patients enrolled in the AIGIS Retrospective Registry to-date it is noteworthy that there is a high percentage of patients who are, according to published studies, at high risk of CRMD-related infections."

                                                             Greater than
                                                             or equal to 1
                                                              Follow-up
       Risk Factors for developing a CRMD       All            Visit
                    infection                 n = 393          n = 254
                                              n     %         n      %
                                     CHF     218   55.5      152    59.8

             Chronic Renal Insufficiency      93   23.7       56    22.1

                   Chronic Renal Failure      41   10.4       24     9.5

                     Oral anti-coagulant     140   35.6       90    35.4

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SOURCE TYRX, Inc.
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