Navigation Links
TAP Pharmaceutical Products Inc. Announces Phase 3 TAK-390MR Data Demonstrating Higher Overall Healing Versus Lansoprazole in Patients with Erosive Esophagitis
Date:5/18/2008

tes for patients with EE. In one study, the life table analysis showed that 93 percent and 95 percent of TAK-390MR patients (60 mg and 90 mg, respectively) experienced healing versus 92 percent of lansoprazole 30 mg patients. The crude rate analysis showed that 87 percent of 60 mg and 89 percent of 90 mg TAK-390MR patients experienced healing versus 85 percent of lansoprazole 30 mg patients.

In a second study, the life table analysis demonstrated that 92 percent of both 60 mg and 90 mg patients experienced healing versus 86 percent of patients on lansoprazole 30 mg. The crude rate evaluation showed that 85 percent and 86 percent of patients treated with TAK-390MR (60 mg and 90 mg, respectively) experienced healing versus 79 percent of patients taking lansoprazole 30 mg. The results for TAK-390MR 90 mg were statistically significantly higher than lansoprazole 30 mg in both studies using crude rate analysis.

The most frequent treatment-related adverse event (AE) for patients in the combined healing studies was diarrhea, which occurred in similar rates across groups (three percent for TAK-390MR 60 mg and 90 mg, versus two percent for lansoprazole 30 mg).

"Findings from both studies demonstrated that patients taking TAK-390MR 60 mg and 90 mg showed numerically higher overall healing than those taking lansoprazole with a similar rate of AEs across groups," said Dr. Prateek Sharma, professor of medicine, gastroenterology section, University of Kansas School of Medicine.

Maintenance of Healed Erosive Esophagitis

TAK-390MR was compared to placebo in a double-blind, randomized, controlled trial in patients with confirmed healing of EE. A total of 445 patients were enrolled in the global, six-month study. The primary objective was to evaluate the overall maintenance rate of healed EE after once-daily administration of TAK-390MR 30 mg, 60 mg, or placebo. A secondary objective was to evaluate the frequency of heartburn over the six-month study
'/>"/>

SOURCE TAP Pharmaceutical Products Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Thomson Scientific Publishes The Ones to Watch - A Quarterly Review of Phase Changes in the Pharmaceutical Pipeline
2. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
3. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
4. Solvay Pharmaceuticals, Inc. and Wyeth Pharmaceuticals Announce Receipt of an FDA Action Letter for Bifeprunox, an Investigational Treatment for Schizophrenia
5. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
6. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
7. WallSt.net (www.wallst.net) Updates the Investment Community Through an All-New Interview With RegeneRx Biopharmaceuticals CEO
8. Par Pharmaceutical Begins Shipment of Additional Dosage Strength of Generic TOPROL-XL(R)
9. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
10. Peregrine Pharmaceuticals Doses First Patient in Cotara(R) Phase II Brain Cancer Trial In India
11. Nabi Biopharmaceuticals Announces Second Quarter 2007 Financial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... and CARDIFF-BY-THE-SEA, Calif. ... (NASDAQ: SRNE ;  Sorrento), an oncology ... pain, and Conkwest, Inc., a privately-held immuno-oncology company ... Killer (NK) cell-line based therapy, announced today that ... to jointly develop next generation CAR-TNK™ (pronounced as ...
(Date:12/19/2014)... , Dec. 18, 2014  Sage Analytics ( ... of equipment for the testing of marijuana potency ... the new Luminary™ Profiler, the industry,s first product ... in a cost-effective, portable unit. Designed ... needs of the cannabis industry, the Luminary™ Profiler ...
(Date:12/19/2014)... , Dec. 18, 2014 Baptist Health Lexington is ... to receive full Atrial Fibrillation with Electrophysiology Services (EPS) ... Atrial fibrillation is the most common cardiac arrhythmia ... some cases can lead to stroke and possible death. More ... have atrial fibrillation and the numbers are rapidly ...
Breaking Medicine Technology:Sorrento and Conkwest Announce Exclusive Global Collaboration 2Sorrento and Conkwest Announce Exclusive Global Collaboration 3Sorrento and Conkwest Announce Exclusive Global Collaboration 4Sorrento and Conkwest Announce Exclusive Global Collaboration 5Sage Analytics Develops Breakthrough System for Potency Testing of Cannabis Products 2Baptist Health Lexington First in the Nation to Receive Atrial Fibrillation with EPS Accreditation 2Baptist Health Lexington First in the Nation to Receive Atrial Fibrillation with EPS Accreditation 3
... 2011 ORTHOCON, Inc., a developer of implantable products designed ... bone, today announced the U.S. launch of its first commercial ... The HEMA SORB Absorbable Bone Hemostat Matrix ... putty that is designed to rapidly stop bleeding when applied ...
... Reportlinker.com announces that a new market ... Drug Device Combination Market ... the New Business Model for Growth and ... Drug Device Combination Market to ...
Cached Medicine Technology:ORTHOCON® Announces U.S. Market Launch of HEMASORB® 2Reportlinker Adds Drug Device Combination Market to 2016 - Technological Convergence to be the New Business Model for Growth and Profitability 2Reportlinker Adds Drug Device Combination Market to 2016 - Technological Convergence to be the New Business Model for Growth and Profitability 3
(Date:12/19/2014)... From November 24, 2014, Siddhi Yoga started ... in its Goa retreat . This is the third ... from November to March, Siddhi Yoga will organize four yoga ... The Goa training sessions will conclude in March 2015. ... the 10th intake is also a 200 YTT ...
(Date:12/19/2014)... The Hermitage Club at Haystack Mountain, ... Deerfield Valley, announced today that it has unveiled its ... , Three time Grammy Award Winner Kenny Loggins ... by a trail naming ceremony. Hermitage Club Founder, President ... Alright” the theme song for the movie soundtrack to ...
(Date:12/19/2014)... Randy Dotinga HealthDay ... -- Common painkillers, including ibuprofen, might slightly reduce your ... say. Use of ibuprofen (Advil, Motrin) and naproxen ... skin cancer by 15 percent, the researchers concluded after ... usually caused by sun exposure. These ...
(Date:12/17/2014)... Nwe is the co-author of a new weight loss book ... the Ace Medical Weight Loss Center in Rock Hill, SC. ... the industry of weight loss, and how several fad diets ... television shows, however, she says the topic of obesity is ... basic laughs, which she believes impacts whether Americans view it ...
(Date:12/17/2014)... December 17, 2014 In its comprehensive ... and its Argus Claim Review division have recently identified ... most common ways savings are achieved on behalf of ... millions of dollars in savings to Argus each year, ... , As explained by Tom Doney, Cypress president and ...
Breaking Medicine News(10 mins):Health News:Siddhi Yoga’s 10th intake of YTT started in Goa on November 24, 2014 2Health News:Siddhi Yoga’s 10th intake of YTT started in Goa on November 24, 2014 3Health News:The Hermitage Club Officially Names Four Ski Trails after Iconic Rock Songs by Grammy Award Winner Kenny Loggins 2Health News:Common Painkillers May Help Prevent Certain Skin Cancers, Study Finds 2Health News:Common Painkillers May Help Prevent Certain Skin Cancers, Study Finds 3Health News:Obesity Should Not Be a Hollywood Punchline, Weight Loss Doc Says 2Health News:Out-of-Network & Medical Necessity Reviews among Top Ways TPA Identifies Significant Medical Claim Savings 2
... tumor which is found resistant to most of the ... The main causative agents for the development of Malignant ... virus 40 (SV40) is also found to be a ... people with malignant mesothelioma have worked or lived in ...
... children sustain at home can be of a grave nature ... result in deaths. ,Researchers at Cincinnati Children's Hospital Medical Center ... the journal Pediatrics// said that preventable injuries sustained at home ... They have studied the results taken from the National Vital ...
... genetic expressions by silencing some expressions of the gene.// ... and health conditions., ,Researchers at UT Southwestern Medical ... produce a drug for the treatment or cure of ... the online edition of the journal Nature Chemical Biology, ...
... and diligence in Britain of Indian origin hit headlines after ... the UK is well known for its long waiting lists ... a routine operation. This has brought NHS under criticism. ... had other ideas on how to deal with the waiting ...
... be easier to diagnose strokes affecting the left-brain than ... issue of The Lancet.// ,The authors state that ... symptoms of right-brain stroke. ,Cerebrovascular events are frequently ... of the brain the lesion occurs. People with events ...
... a recent study published for the first time, researchers ... oxidized phospholipids and the risk of coronary artery disease ... those of Lp(a) lipoprotein, the researchers suggest that that ... may be partly mediated by the proinflammatory oxidized phospholipids ...
Cached Medicine News:Health News:Malignant Mesothelioma – A New Genetic Revelatio 2Health News:Malignant Mesothelioma – A New Genetic Revelatio 3Health News:Indian Surgeon Conducts 70 Surgeries During His Holidays In England 2Health News:Stroke In The Right-Brain Can Remain Undiagnosed 2Health News:The Link Between Oxidized Phospholipids And Coronary Artery Disease 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: