Navigation Links
T1D Exchange Awarded $2.8M Grant by JDRF to Study Metformin and Type 1 Diabetes
Date:11/1/2013

BOSTON, Nov. 1, 2013 /PRNewswire/ -- T1D Exchange, the first program of the new nonprofit organization Unitio, has received a $2.8 million research grant from JDRF to study the use of metformin—a drug used as first-line treatment for type 2 diabetes—in combination with standard insulin therapy in overweight adolescents with type 1 diabetes.

The study will include a minimum of 136 adolescents with type 1 diabetes who are overweight and have failed to achieve optimal blood sugar control with insulin alone. Study participants will continue insulin therapy and will be randomly assigned to receive either metformin or a placebo. Blood sugar control and side effects of the treatment will be assessed over a 6-month period.  In a concurrent study involving a subset of the participants, testing will be done to assess whether metformin improves insulin sensitivity.

"We are very excited to partner with JDRF in this important study to better understand the benefits and risks of the use of metformin in overweight adolescents with type 1 diabetes and evidence of insulin resistance," said Dana Ball, executive director and co-founder of T1D Exchange. "JDRF and T1D Exchange share the goal of improving the lives of people with type 1 diabetes, and we look forward to future collaborative opportunities."

The efficacy of metformin, a drug that is used to control the amount of glucose in the blood of those with type 2 diabetes, is largely unknown for those with type 1 diabetes.

"For more than 90 years, insulin has been the primary therapy for people with type 1 diabetes; but the fact remains that despite vigilant management, glycemic control is a huge challenge for many with the disease," said Sanjoy Dutta, Ph.D., senior director of treat therapies at JDRF. "Previous studies have built a body of evidence showing the potential of certain adjunct therapi
'/>"/>

SOURCE T1D Exchange
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Immune Pharmaceuticals Appoints Liquidity Provider to Facilitate Trading on NASDAQ OMX Stockholm Exchange
2. U.S. Physician Prescribing Behavior Impacted by Health Insurance Exchanges and Accountable Care Organizations
3. InspireMD to Ring Opening Bell at New York Stock Exchange on Thursday, October 24th
4. Assured Pharmacy, Inc. Announces 16% Senior Convertible Debenture and Warrant Exchange Offer
5. Singh & Associates and Sughrue Mion PLLC in association with Lex WITNESS present The IPR Exchange - An Indo US IPR Summit
6. Alere Inc. Extends Exchange Offer for 6.500% Senior Subordinated Notes due 2020
7. Experian Healthcare launches tool to enable providers to identify and help enroll eligible individuals for health insurance exchange (HIX) subsidized programs
8. Immune Pharmaceuticals Inc. Trading Symbol is Now IMNP on Both NASDAQ OMX Stockholm Exchange and OTCQX Trading Platform
9. New Research Finds Many Seniors Wrongly Think Public Health Insurance Exchanges Are Replacing Medicare Plans
10. Southeast Michigan Beacon Community to Integrate Laboratory Tests from Quest Diagnostics Into BeaconLink2Health Health Information Exchange
11. CVS Caremark Announces Agreement in Principle with the Securities and Exchange Commission
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/21/2014)... Nov. 21, 2014  Lexicon Pharmaceuticals, Inc. (Nasdaq: ... previously announced underwritten public offering of $50,000,000 of shares ... registration statement. The offering will consist of 49,751,244 shares ... $1.005 per share.  Lexicon has also granted the underwriters ... shares of common stock.  All of the shares in ...
(Date:11/18/2014)... MOUNT LAUREL, N.J. , Nov. 18, 2014 ... more than 230,000 American women this year who ... Manager Certification® today announced new resources for case ... cancer—stages 4 and 5—to navigate the myriad physical, ... territory. The resources are available at no cost ...
(Date:11/18/2014)... 18, 2014 SynCardia Systems, Inc., has been ... for Small Companies presented by the Arizona Technology Council ... The 11th annual Governor,s Celebration of Innovation Awards honor ... . Arizona Governor Jan ... SynCardia was honored for its Freedom® portable driver, which ...
Breaking Medicine Technology:Lexicon Announces Pricing Of Common Stock Offering 2Lexicon Announces Pricing Of Common Stock Offering 3New Breast Cancer Resources: Commission For Case Manager Certification Adds Specialty Tools to Case Management Body of Knowledge Online Learning Center 2SynCardia Named Innovator of the Year by the 2014 Governor's Celebration of Innovation Awards for Its Freedom Portable Driver 2SynCardia Named Innovator of the Year by the 2014 Governor's Celebration of Innovation Awards for Its Freedom Portable Driver 3
... GENR ) today reported data from its second ... candidate,for the treatment of type 2 diabetes and obesity. ... target that controls the function,of both the leptin and ... study, MSI-1436 was found to be well-tolerated and no,serious ...
... 60 percent of moderate to severe patients achieved ... remission at Week 10,in data from a 54-week ... (ACG) Annual Scientific Meeting, ORLANDO, Fla., Oct. ... prospective study investigating endoscopic improvement in Crohn,s,disease (CD) ...
Cached Medicine Technology:Genaera Corporation Reports Phase 1 Data for Trodusquemine (MSI-1436) at the North American Association for the Study of Obesity Annual Meeting 2Genaera Corporation Reports Phase 1 Data for Trodusquemine (MSI-1436) at the North American Association for the Study of Obesity Annual Meeting 3Genaera Corporation Reports Phase 1 Data for Trodusquemine (MSI-1436) at the North American Association for the Study of Obesity Annual Meeting 4CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohn's Patients 2CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohn's Patients 3CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohn's Patients 4CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohn's Patients 5CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohn's Patients 6CIMZIA(R) (certolizumab pegol) Reduces Intestinal Lesions and Induces Endoscopic Improvement in Crohn's Patients 7
(Date:11/21/2014)... Angeles, CA (PRWEB) November 21, 2014 ... reference for the dental practice. It includes everything needed ... . , Procedure Coding with CDT , CDT 2015 ... provided from January 1, 2014 - December 31, 2014. ... report procedures and services on dental claims. There are ...
(Date:11/21/2014)... Even with years of experience under his belt, ... for growth, participating in two recent events for his State ... a networking event with the leaders of State Farm and ... latest and greatest in insurance news and products for his ... team (Stacy, Anthony, Reina and Jacob) as exhibitors at the ...
(Date:11/21/2014)... (PRWEB) November 21, 2014 CARE Surrogacy ... its intended parents — and at the same time enhancing ... sense of optimism for future parents across the globe, the ... , Prospective parents today are zoning in on the skyrocketing ... the encumbering costs, are individuals over-stressing clinical success rates ...
(Date:11/21/2014)... 21, 2014 According to a National ... June 11th, 2014, the inflating system found in certain ... airbag inflates. The force of inflation may cause the ... metal shards may pierce the airbag’s fabric and potentially ... , According to a Bloomberg Business Week article ...
(Date:11/21/2014)... 2014 Nature’s Sleep is excited to announce the ... contest calls for the creation of any type of art — ... encompasses sleep, a bed or a mattress. , “We had ... Vice President of Marketing for Nature’s Sleep, “that we decided to ... than 10,000 creative entries from some very talented artists all the ...
Breaking Medicine News(10 mins):Health News:PMIC Announces CDT PLUS! 2015, the Ultimate Coding Reference for Dentists and Oral Surgeons 2Health News:Kirk Martin Insurance Agency Goes Local and National with State Farm 2Health News:CARE Surrogacy Center Reports on its Multiple Measures of Success 2Health News:CARE Surrogacy Center Reports on its Multiple Measures of Success 3Health News:Takata Airbag Recall Class Action Lawsuit Resource Released by Florida Injury Attorney 2Health News:Takata Airbag Recall Class Action Lawsuit Resource Released by Florida Injury Attorney 3Health News:Nature’s Sleep Kicks Off their 2nd Art Of Sleep Contest 2
... The chances of suffering a stroke are linked to the ... system, a new study from Karolinska Institutet shows. The researchers ... mobilise the body,s own defence against arteriosclerosis and stroke. ... Frostegrd, has previously demonstrated that high levels of a certain ...
... taking action, study finds , FRIDAY, Feb. 12 ... opening in Canada Friday seem more on the ball ... activity enables elite athletes to see and react to ... new study finds. , Researchers analyzed the reaction time ...
... successfully inserted to reopen clogged coronary artery , THURSDAY, ... was said to be "in good spirits" Thursday evening ... two stents inserted into a clogged heart artery. , ... 2004, had been complaining of chest pains. , "Today ...
... , ... in Twin Cities , ... February 12, 2010 -- Ecumen an innovative non-profit senior housing, services and ... on its second senior housing community in Apple Valley and will manage The Seasons at ...
... ... to an underage passenger hurt in a vehicle crash after he left a party. ... Providence, RI (PRWEB) February 12, ... the liability homeowners face when they allow underage drinking in their homes., , ,Details of ...
... , ... Qigong has been called the secret of youth and longevity, and in his latest book, ... Eastern movements can slow the ageing process down and promote youthful skin from the inside ... (PRWEB) February 12, ...
Cached Medicine News:Health News:Ex-President Clinton Said To Be Fine After Heart Procedure 2Health News:Ex-President Clinton Said To Be Fine After Heart Procedure 3Health News:Ecumen Building Senior Housing in Apple Valley, Minnesota and Will Manage New Maplewood, Minnesota Property 2Health News:Ecumen Building Senior Housing in Apple Valley, Minnesota and Will Manage New Maplewood, Minnesota Property 3Health News:Rhode Island Settlement Reflects Homeowner Liability for Serving Alcohol to Those Under 21, Says Providence Lawyer Mark Gemma 2Health News:New Book Reveals How Qigong Could Be The Eastern Answer To Botox 2
... designed with the safety and comfort of the ... (also called SF-6) leaded glass, the industry standard ... as set for optical clarity, visible light transmission, ... is protecting your eyes, it also helps you ...
Panoramic styling that contours closely to the face and brow. Saddle bridge fits average to fuller noses. Adjustable temple hinge adjusts up or down, longer or shorter. Soft cushion behind ear for co...
Qualcraft™ Radiation Protection Eyewear, Metal, Bifocal. Provides maximum comfort and eye protection! Plano (nonprescription). Black with bronze temple bar....
QualCraft™ Radiation-Reducing Eyewear is 50% lighter than other protective eyewear. Manufactured for the ultimate combination of comfort, function, and protection....
Medicine Products: