Navigation Links
Synvista Therapeutics Announces Published Data Demonstrating Elevation of Carboxymethyl-Lysine (CML) Is Associated with Decline in Renal Function and Arterial Stiffness in Older Adults
Date:12/16/2008

Synvista Therapeutics Technology Provided CML Biomarker Data for Studies

MONTVALE, N.J., Dec. 16 /PRNewswire-FirstCall/ -- Synvista Therapeutics, Inc. (NYSE Alternext US: SYI) today announced two publications demonstrating findings from studies that indicated that the presence of the advanced glycation end product (A.G.E.) called carboxymethyl-lysine (CML) in older adults is associated with a decline in renal function and arterial stiffness in older adults. Kits developed through a license to Synvista's technology were used in these studies. Synvista is validating this clinical diagnostic assay as it prepares to submit a CML kit for 510(k) clearance in the second half of 2009.

"These studies represent an important next step in our understanding of the role of CML in an elderly population, and they provide physicians more information that may be useful in the prevention of cardiovascular and renal disease, particularly in older adults," said Richard D. Semba, M.D., M.P.H, W. Richard Green Professor of Ophthalmology, The Johns Hopkins University School of Medicine and lead author of both studies. "As we have learned, the elevation of CML is preventable in many cases, as it can be mitigated by changes in diet. Therefore, to bring a clearer understanding of this A.G.E. to the forefront may help doctors better explain to their patients how to help prevent cardiovascular and renal complications."

In one study, published in a recent edition of American Journal of Hypertension, investigators measured 493 adult subjects participating in the Baltimore Longitudinal Study of Aging for their aortic pulse wave velocity (an index of aortic stiffness) and CML (using Synvista's proprietary technology). Results demonstrated that elevated levels of CML in these subjects corresponded to increased arterial stiffness, a known predictor of cardiovascular disease.

T
'/>"/>

SOURCE Synvista Therapeutics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

2

GOOD

Page: 1 2 3 4 5

Related medicine technology :

1. Synvista Therapeutics Announces First Dosing of SYI-2074 in Clinical Trial for Psoriasis
2. Data Confirm Synvista Therapeutics Haptoglobin Diagnostic Test Kit Success in Rapidly Determining Cardiovascular Risk in Patients with Diabetes
3. Synvista Therapeutics Reports Results of Three Phase 2 Clinical Trials of SYI-2074 in Diabetic Patients with Cardiovascular Disease
4. Synvista Therapeutics Presents New Preclinical Data Demonstrating the Value of Haptoglobin Genotype Testing In Diabetes at ACC Scientific Sessions
5. Synvista Therapeutics Announces Initiation of Phase 2 Study With Alagebrium for Chronic Heart Failure
6. Synvista Announces New Data Showing Haptoglobin Type Predicts Effectiveness of Tight Glycemic Control on Cardiovascular Outcomes in Patients with Diabetes
7. Synvista Collaboration Demonstrates in Preclinical Studies the Mechanism for Defective Cholesterol Transport in Patients with Diabetes
8. Synvista Therapeutics Highlights New Data Demonstrating the Clinical Benefit of Vitamin E Therapy in Patients Identified on the Basis of Haptoglobin Phenotype Testing
9. Synvista Therapeutics Alagebrium Shows Potential for use in Treating Diabetes-Related Gastrointestinal Complications
10. Halozyme Therapeutics Begins Phase 1 Clinical Trial of Bisphosphonate Administered With rHuPH20 Enzyme
11. Halozyme Therapeutics Announces Roche Begins Phase 1 Clinical Trial and Selects Fourth Exclusive Biologic Target
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/18/2013)... MPR is excited to unveil a new ... all part of an ongoing effort to freshen the look ... over 28 years. (Photo: http://photos.prnewswire.com/prnh/20130618/NY33937 ... MPR has expanded upon its foundation as a concise ... an increasing array of clinical and practice management tools including ...
(Date:6/18/2013)... June 18, 2013 New-generation electronic designs ... portable and lightweight. Simultaneously, circuitry is increasing the ... speed to which it performs at. Connecting cables ... and military equipment, such as cameras or detectors, ... and nano-circular connectors include custom cable designs for ...
(Date:6/18/2013)... Apama Medical, a privately held medical ... atrial fibrillation technologies, today announced the issuance of ... and Trademark Office (USPTO), titled "Low Profile Electrodes". ... use on expandable structures such as balloons used ... "We are grateful to the NSF SBIR ...
Breaking Medicine Technology:MPR Sports a Bold New Look 2Omnetics Circular Connectors Offer Both Micro and Nano Interconnects for Highly Portable Electronic Systems, Meeting the Needs of Designers Looking for Size Reduction Options and Cable Flexibility 2
... SALT LAKE CITY , May 11 Dynatronics Corporation (Nasdaq: DYNT ... during the morning of Monday, May 17, 2010 .   , ... Dynatronics has scheduled a conference call for investors later that ...  Those interested in participating should call 800-861-4084 and use passcode: 9921511. , ...
... 11 RF Technologies®, a leading provider of healthcare safety and ... use with Safe Place® Infant Security Solutions. The soft, stretchy banding material ... staff when a Safe Place bracelet is loose, tampered with or is ... Smart Sense ...
Cached Medicine Technology:Smart Sense(TM) From RF Technologies Upgrades Safe Place(R) Bracelets Using Industry-Leading Infant Security Technology, Fit and Comfort 2
(Date:6/19/2013)... 2013 MinuteHound, a leading time and ... save businesses up to 8% on payroll costs. MinuteHound’s ... time card systems. Their biometric system is simple: Employees ... clocks them in and out automatically. Employee time ... and buddy punching. , Because the fingerprint data ...
(Date:6/19/2013)... 19, 2013 Over the past five ... industry has been growing at an annualized rate ... Many factors have supported the development of the industry ... by drugstores; relatively higher drug prices in hospitals; and ... support for the development of chain drug retailing enterprises ...
(Date:6/18/2013)... 19, 2013 "What if adding one ... could boost your health and well-being? Well, there is ... Sublime Beauty®. "It is called Skin Brushing ." ... became a lost art. Now, people are rediscovering this ... Brushing, and so do certain health conscious people. Sublime ...
(Date:6/18/2013)... York, NY (PRWEB) June 18, 2013 Cheap ... tickets for the tournament which gets underway in July. ... savings on any CONCACAF ticket order. , The ... and cranny of the globe.    In fact, the hype of the ... Its popularity also trickled down the veins of fans ...
(Date:6/18/2013)... 2013 The Temp1000IS temperature data ... device which can be used to automatically record temperatures ... of the Temp1000IS comes with the serial number and ... IFC400 (sold separately) docking station and can be ... No more removal of end-caps to download data. The ...
Breaking Medicine News(10 mins):Health News:MinuteHound Announces How Cloud Computing Technology Boosts Savings 2Health News:MinuteHound Announces How Cloud Computing Technology Boosts Savings 3Health News:Pharmacies and Drug Retailers in China Industry Research Report – Now Available from IBISWorld 2Health News:Pharmacies and Drug Retailers in China Industry Research Report – Now Available from IBISWorld 3Health News:The Easiest Way to Contribute to Better Health and Well-Being Starting Today and for Under $20, Says Sublime Beauty® 2Health News:CONCACAF Tickets Have Been Released for Martinique, Mexico, Panama, El Salvador, Trinidad, Tobago, Haiti, Honduras, Costa Rica, Cuba, Belize, US, Canada, Honduras & Cuba 2Health News:CONCACAF Tickets Have Been Released for Martinique, Mexico, Panama, El Salvador, Trinidad, Tobago, Haiti, Honduras, Costa Rica, Cuba, Belize, US, Canada, Honduras & Cuba 3Health News:MadgeTech, Inc. Introduces the New Temp1000IS Intrinsically Safe High Temperature Data Logger 2
... , , BALA CYNWYD, ... pleased to announce it will begin offering Chiropractor,s Malpractice ... policies in Alabama, California, Colorado, Idaho, Montana, South Dakota ... Ohio and Texas within the next 60 days with ...
... , WASHINGTON, Dec. 23 With the House having passed its ... the verge of passing its version (H.R. 3590), the outline of ... new Issue Brief , The Concord Coalition looks ahead at the ... discussions and "end game" negotiations. These include the cost of expanding ...
... A new study in the journal Infection Control and ... Acinetobacter, a dangerous type of bacteria that is becoming ... posted online today and will appear in the journal,s ... intensive care units (ICUs) and others and have recently ...
... to dirty air doubled likelihood of respiratory infection, study ... who are exposed to significant levels of air pollution ... of pneumonia, Canadian researchers report. , "We postulate that ... susceptibility to pneumonia by interfering with innate immune defenses ...
... 23 Governor Edward G. Rendell today said Pennsylvanians who ... now may qualify for two more months of emergency unemployment ... , "The continuation of federal UC benefits and health ... Pennsylvanians this holiday season," said Governor Rendell. "Now, more families ...
... This release is available in German . ... keep us mentally fit. Some products even claim that brain training ... proof that games or other brain exercises can have this effect. ... Health Care (IQWiG) pointed out in information published on informedhealthonline.org ...
Cached Medicine News:Health News:Philadelphia Insurance Companies Introduces Chiropractor Professional Liability Product 2Health News:New Concord Coalition Paper Discusses 'End Game' Fiscal Considerations for Health Care Reform 2Health News:New study shows rise in drug resistance of dangerous infection in US hospitals 2Health News:Pollution May Boost Pneumonia Risk for Seniors 2Health News:Governor Rendell: Extension of Emergency Unemployment Compensation, COBRA Provides Immediate Financial Help to Pennsylvanians 2Health News:Brain training can help improve specific abilities in older people 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: