Navigation Links
Synvista Therapeutics Announces Published Data Demonstrating Elevation of Carboxymethyl-Lysine (CML) Is Associated with Decline in Renal Function and Arterial Stiffness in Older Adults
Date:12/16/2008

Synvista Therapeutics Technology Provided CML Biomarker Data for Studies

MONTVALE, N.J., Dec. 16 /PRNewswire-FirstCall/ -- Synvista Therapeutics, Inc. (NYSE Alternext US: SYI) today announced two publications demonstrating findings from studies that indicated that the presence of the advanced glycation end product (A.G.E.) called carboxymethyl-lysine (CML) in older adults is associated with a decline in renal function and arterial stiffness in older adults. Kits developed through a license to Synvista's technology were used in these studies. Synvista is validating this clinical diagnostic assay as it prepares to submit a CML kit for 510(k) clearance in the second half of 2009.

"These studies represent an important next step in our understanding of the role of CML in an elderly population, and they provide physicians more information that may be useful in the prevention of cardiovascular and renal disease, particularly in older adults," said Richard D. Semba, M.D., M.P.H, W. Richard Green Professor of Ophthalmology, The Johns Hopkins University School of Medicine and lead author of both studies. "As we have learned, the elevation of CML is preventable in many cases, as it can be mitigated by changes in diet. Therefore, to bring a clearer understanding of this A.G.E. to the forefront may help doctors better explain to their patients how to help prevent cardiovascular and renal complications."

In one study, published in a recent edition of American Journal of Hypertension, investigators measured 493 adult subjects participating in the Baltimore Longitudinal Study of Aging for their aortic pulse wave velocity (an index of aortic stiffness) and CML (using Synvista's proprietary technology). Results demonstrated that elevated levels of CML in these subjects corresponded to increased arterial stiffness, a known predictor of cardiovascular disease.

T
'/>"/>

SOURCE Synvista Therapeutics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Synvista Therapeutics Announces First Dosing of SYI-2074 in Clinical Trial for Psoriasis
2. Data Confirm Synvista Therapeutics Haptoglobin Diagnostic Test Kit Success in Rapidly Determining Cardiovascular Risk in Patients with Diabetes
3. Synvista Therapeutics Reports Results of Three Phase 2 Clinical Trials of SYI-2074 in Diabetic Patients with Cardiovascular Disease
4. Synvista Therapeutics Presents New Preclinical Data Demonstrating the Value of Haptoglobin Genotype Testing In Diabetes at ACC Scientific Sessions
5. Synvista Therapeutics Announces Initiation of Phase 2 Study With Alagebrium for Chronic Heart Failure
6. Synvista Announces New Data Showing Haptoglobin Type Predicts Effectiveness of Tight Glycemic Control on Cardiovascular Outcomes in Patients with Diabetes
7. Synvista Collaboration Demonstrates in Preclinical Studies the Mechanism for Defective Cholesterol Transport in Patients with Diabetes
8. Synvista Therapeutics Highlights New Data Demonstrating the Clinical Benefit of Vitamin E Therapy in Patients Identified on the Basis of Haptoglobin Phenotype Testing
9. Synvista Therapeutics Alagebrium Shows Potential for use in Treating Diabetes-Related Gastrointestinal Complications
10. Halozyme Therapeutics Begins Phase 1 Clinical Trial of Bisphosphonate Administered With rHuPH20 Enzyme
11. Halozyme Therapeutics Announces Roche Begins Phase 1 Clinical Trial and Selects Fourth Exclusive Biologic Target
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... 28, 2014  VigeneTech, Inc, in collaboration with ... Data Analysis Software, an OEM software solution for ... develops and offers varieties of bead-based multi-analyte immunoassay ... support of VigeneTech,s data analysis software, FCS data ... easily reported LEGENDplex™ software is ...
(Date:7/28/2014)... 28, 2014  A prospective study conducted by ... has validated the performance of VolparaDensity breast ... associated volumetrically assessed breast density measurements to breast ... & Prevention (DOI: 10.1158/1055-9965.EPI-13-1219), the article, "Automated ... widespread breast cancer risk assessment," was authored by ...
(Date:7/28/2014)... Calif. , July 28, 2014 ... leader in lifestyle healthcare and subsidiary ... that it has acquired Physician Recommended Nutriceuticals (PRN) ... omega-3s, and related products for dry ... Plymouth Meeting, PA, in a transaction worth up ...
Breaking Medicine Technology:VigeneTech Releases New Powerful Software for Flow Cytometry Data Analysis 2Karolinska Study Published in Cancer Epidemiology, Biomarkers & Prevention Validates Strong Agreement for VolparaDensity across Mammography Systems from Multiple Manufacturers 2Karolinska Study Published in Cancer Epidemiology, Biomarkers & Prevention Validates Strong Agreement for VolparaDensity across Mammography Systems from Multiple Manufacturers 3Karolinska Study Published in Cancer Epidemiology, Biomarkers & Prevention Validates Strong Agreement for VolparaDensity across Mammography Systems from Multiple Manufacturers 4ALPHAEON Acquires PRN, A Leading Specialty Nutriceutical Company 2ALPHAEON Acquires PRN, A Leading Specialty Nutriceutical Company 3
... guide low-income,and minority cancer patients through cancer treatment, ... major obstacles that prevent them,from receiving quality care ... October 28, 2007, at the American Society for ... Angeles. Minority and low-income cancer patients continue ...
... FLUSHING, N.Y., Oct. 30 The following is,being issued by New York Hospital Queens:, ... aureus(MRSA) is scheduled for ... James Rahal, M.D., and a team of infectious disease ... will address the ...
Cached Medicine Technology:Patient Navigators Help Minority, Low-Income Cancer Patients Get Life-Saving Treatments 2Hospital to Hold MRSA Briefing for Media and Community Leaders 2
(Date:7/28/2014)... 28, 2014 Ticket Down is ... Champions Cup Match between Manchester City and Liverpool FC ... Bronx has hosted countless big events since it opened several ... of the original Yankee Stadium, however, it has been a ... City metro area. , The Yankees Stadium is the ...
(Date:7/28/2014)... 2014 A January 2013 study ... intake in those who were self-diagnosed gluten-intolerant yielded little ... nutrition for San Diego health and wellness retreat ... for those who are unclear about the role gluten ... is a protein, found in wheat, barley, rye, and ...
(Date:7/28/2014)... Dawn Echols’ professional background spans ... music. This experience has honed her people skills ... Her professional counseling ( http://dawningphoenix.com ) work includes ... offenders in domestic violence. , As owner ... enjoys counseling individuals and groups for a variety ...
(Date:7/28/2014)... 28, 2014 Ticket Down is ... tickets in Dallas, TX at the Cotton Bowl. The ... the USA and it is an eight team tourney. ... world including teams from La Liga, Serie A, English Premier ... battle it out on the pitch include: Manchester United, ...
(Date:7/28/2014)... Massachusetts (PRWEB) July 28, 2014 ... Summit Provider Exchange technology solution in ... integration efforts and support collaboration with their New ... bed acute-care medical center located in New Jersey, ... seasonal visitors with a variety of inpatient and ...
Breaking Medicine News(10 mins):Health News:Liverpool FC vs. Manchester City Tickets at Yankee Stadium: Ticket Down Reports Huge Demand for Guinness International Champions Cup Tickets in NYC 2Health News:Liverpool FC vs. Manchester City Tickets at Yankee Stadium: Ticket Down Reports Huge Demand for Guinness International Champions Cup Tickets in NYC 3Health News:VeraVia Explains the Basics of Gluten-Intolerance Following Industry Study 2Health News:VeraVia Explains the Basics of Gluten-Intolerance Following Industry Study 3Health News:Dawn M. Echols, M.S., LPC of Dawning Phoenix Speaks at Newly Formed Task Force 2Health News:Real Madrid vs. AS Roma Tickets Cotton Bowl Dallas, TX: Ticket Down Cuts Ticket Prices for AS Roma vs. Real Madrid International Champions Cup Tickets 2Health News:Real Madrid vs. AS Roma Tickets Cotton Bowl Dallas, TX: Ticket Down Cuts Ticket Prices for AS Roma vs. Real Madrid International Champions Cup Tickets 3Health News:Cape Regional Medical Center Chooses Summit Provider Exchange to Connect With NJSHINE and Physician Offices 2Health News:Cape Regional Medical Center Chooses Summit Provider Exchange to Connect With NJSHINE and Physician Offices 3
... ... RXinnovate, a healthcare consultancy, to offer top-of-the-line implementation services to Talyst’s clients in ... ... 44th Annual Midyear Clinical Meeting of the American Society of Health-System Pharmacists in ...
... , ATLANTA, Dec. 7 Results of two ... the antiepileptic drug (AED) Vimpat® for patients requiring add-on therapy ... feasible. These data, which were presented by UCB at ... Boston, further clarify the role of intravenous Vimpat in the ...
... , , NEW ORLEANS, Dec. 7 ... developing novel, proprietary antibodies for the treatment of cancer, ... a poster(1) with new data from its ongoing phase ... patients with non-Hodgkin,s lymphoma (NHL) at the 51ST Annual ...
... , MIAMI, Dec. 7 A couple years ... searching frantically for gifts made in the USA. This fall, ... toys are suspect. Renowned parenting expert Dr. Jeffrey Fine, Ph.D., ... retarding language development and shortening attention spans. Moreover, there is ...
... ... chairman of the board of directors for PerfectServe, a clinical communications company currently serving ... ... Gene Barduson was recently named executive chairman of the board of directors for ...
... , WEST PALM BEACH, Fla., Dec. 7 The ... to publicize the first major innovation in hospital privacy ... is already saving hospitals millions in maintenance costs. , ... Record to elevate Cubicle Curtain Factory,s profile in print, broadcast, ...
Cached Medicine News:Health News:Talyst and RXinnovate Partner on Pharmacy Automation Implementation 2Health News:New Studies Support Use of Intravenous Vimpat(R) (lacosamide) (C-V) in Hospital and Emergency Settings 2Health News:New Studies Support Use of Intravenous Vimpat(R) (lacosamide) (C-V) in Hospital and Emergency Settings 3Health News:New Studies Support Use of Intravenous Vimpat(R) (lacosamide) (C-V) in Hospital and Emergency Settings 4Health News:New Studies Support Use of Intravenous Vimpat(R) (lacosamide) (C-V) in Hospital and Emergency Settings 5Health News:Data from Phase 1 Study Confirm High Response Rate of Micromet's Blinatumomab in Patients with Non-Hodgkins Lymphoma 2Health News:Data from Phase 1 Study Confirm High Response Rate of Micromet's Blinatumomab in Patients with Non-Hodgkins Lymphoma 3Health News:Data from Phase 1 Study Confirm High Response Rate of Micromet's Blinatumomab in Patients with Non-Hodgkins Lymphoma 4Health News:Top 10 Toys That Will Scar Your Child for Life 2Health News:Gene Barduson Named Chairman of PerfectServe Board of Directors 2Health News:Cubicle Curtain Factory Retains TransMedia Group to Promote First Privacy Curtain to Reduce Hospital Maintenance Cost 2
... Simple, cost-effective microfiltration for your transfusion ... also brings you an easy and ... of microfiltration for a variety of ... postoperative applications, autologous or homologous transfusions, ...
This high technology cast plaster cutter saw is very easy and comfortable to use....
... Designed to reduce noise to a minimum ... and less hearing trauma for the clinician. ... high power in a smaller, lighter package. ... saw's balance and ergonomics for more user ...
The True/Fix Cannulated Bone Screw System contains 7.0mm large cannulated bone screws and 3.5mm cortical and 4.0mm cannulated cancellous bone screws....
Medicine Products: