Navigation Links
Synvista Therapeutics Announces Published Data Demonstrating Elevation of Carboxymethyl-Lysine (CML) Is Associated with Decline in Renal Function and Arterial Stiffness in Older Adults
Date:12/16/2008

Synvista Therapeutics Technology Provided CML Biomarker Data for Studies

MONTVALE, N.J., Dec. 16 /PRNewswire-FirstCall/ -- Synvista Therapeutics, Inc. (NYSE Alternext US: SYI) today announced two publications demonstrating findings from studies that indicated that the presence of the advanced glycation end product (A.G.E.) called carboxymethyl-lysine (CML) in older adults is associated with a decline in renal function and arterial stiffness in older adults. Kits developed through a license to Synvista's technology were used in these studies. Synvista is validating this clinical diagnostic assay as it prepares to submit a CML kit for 510(k) clearance in the second half of 2009.

"These studies represent an important next step in our understanding of the role of CML in an elderly population, and they provide physicians more information that may be useful in the prevention of cardiovascular and renal disease, particularly in older adults," said Richard D. Semba, M.D., M.P.H, W. Richard Green Professor of Ophthalmology, The Johns Hopkins University School of Medicine and lead author of both studies. "As we have learned, the elevation of CML is preventable in many cases, as it can be mitigated by changes in diet. Therefore, to bring a clearer understanding of this A.G.E. to the forefront may help doctors better explain to their patients how to help prevent cardiovascular and renal complications."

In one study, published in a recent edition of American Journal of Hypertension, investigators measured 493 adult subjects participating in the Baltimore Longitudinal Study of Aging for their aortic pulse wave velocity (an index of aortic stiffness) and CML (using Synvista's proprietary technology). Results demonstrated that elevated levels of CML in these subjects corresponded to increased arterial stiffness, a known predictor of cardiovascular disease.

T
'/>"/>

SOURCE Synvista Therapeutics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Synvista Therapeutics Announces First Dosing of SYI-2074 in Clinical Trial for Psoriasis
2. Data Confirm Synvista Therapeutics Haptoglobin Diagnostic Test Kit Success in Rapidly Determining Cardiovascular Risk in Patients with Diabetes
3. Synvista Therapeutics Reports Results of Three Phase 2 Clinical Trials of SYI-2074 in Diabetic Patients with Cardiovascular Disease
4. Synvista Therapeutics Presents New Preclinical Data Demonstrating the Value of Haptoglobin Genotype Testing In Diabetes at ACC Scientific Sessions
5. Synvista Therapeutics Announces Initiation of Phase 2 Study With Alagebrium for Chronic Heart Failure
6. Synvista Announces New Data Showing Haptoglobin Type Predicts Effectiveness of Tight Glycemic Control on Cardiovascular Outcomes in Patients with Diabetes
7. Synvista Collaboration Demonstrates in Preclinical Studies the Mechanism for Defective Cholesterol Transport in Patients with Diabetes
8. Synvista Therapeutics Highlights New Data Demonstrating the Clinical Benefit of Vitamin E Therapy in Patients Identified on the Basis of Haptoglobin Phenotype Testing
9. Synvista Therapeutics Alagebrium Shows Potential for use in Treating Diabetes-Related Gastrointestinal Complications
10. Halozyme Therapeutics Begins Phase 1 Clinical Trial of Bisphosphonate Administered With rHuPH20 Enzyme
11. Halozyme Therapeutics Announces Roche Begins Phase 1 Clinical Trial and Selects Fourth Exclusive Biologic Target
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/5/2015)... Columbia , May 5, 2015  InMed ... clinical stage biopharmaceutical company that specializes in developing ... former GW Pharmaceuticals financier, investor, and Non-Executive Director, ... InMed as Strategic Advisor with primary responsibility for ... role, Mr. Mountford will leverage his previous success ...
(Date:5/4/2015)... VANCOUVER, British Columbia , May 4, ... announced today that it will report its first quarter ... management will host a conference call and live webcast ... of financial results, clinical development programs and a general ... log on to the Investor Relations page of the ...
(Date:5/4/2015)...  Amgen (NASDAQ: AMGN ) will present at the ... on Thursday, May 7, 2015, at the InterContinental in ... vice president of Global Commercial Operations at Amgen, will present ... accessed from the Events Calendar on Amgen,s website, www.amgen.com ... be available on Amgen,s website for 90 days following the ...
Breaking Medicine Technology:InMed Engages Peter Mountford as Strategic Advisor 2InMed Engages Peter Mountford as Strategic Advisor 3InMed Engages Peter Mountford as Strategic Advisor 4Amgen To Present At The Deutsche Bank 40th Annual Healthcare Conference 2
... 10, 2010 Mylan Inc. (Nasdaq: MYL ... conversion rate applicable to its 6.50% Mandatory Convertible Preferred ... common stock of the company effective as of November ... the governing provisions of the company,s Amended and Restated ...
... Pharmaxis, a global specialty pharmaceutical company focused on therapeutic ... (mannitol inhalation powder) Bronchial Challenge Test Kit, at the ... Asthma and Immunology (ACAAI), November 11-16 in Phoenix, AZ. ... Drug Administration (FDA) on October 5, 2010, ARIDOL is ...
Cached Medicine Technology:Pharmaxis Previews New Bronchial Challenge Test at the Annual Meeting of the American College of Allergy, Asthma and Immunology 2Pharmaxis Previews New Bronchial Challenge Test at the Annual Meeting of the American College of Allergy, Asthma and Immunology 3Pharmaxis Previews New Bronchial Challenge Test at the Annual Meeting of the American College of Allergy, Asthma and Immunology 4Pharmaxis Previews New Bronchial Challenge Test at the Annual Meeting of the American College of Allergy, Asthma and Immunology 5
(Date:5/4/2015)... UK (PRWEB) May 04, 2015 During ... witness a 7.7% CAGR. Currently, the European and APAC ... world, while the North American probiotic market lags behind ... local population. , The North American probiotic market ... over 58%), followed by Canada and Mexico. The North ...
(Date:5/4/2015)... May 04, 2015 HHT is a ... generations. While it can have seemingly mild symptoms ... catastrophic events. Hereditary Hemorrhagic Telangiectasia (HHT) is a ... that lack normal capillary connections between an artery and ... frequent, severe nosebleeds, but may also be present in ...
(Date:5/4/2015)... 2015 Milton Hershey School® has named ... of the Year, recognizing his commitment to pediatric cancer ... sets for MHS students. , “Dr. Graves is a ... children are provided a top-notch education, a nurturing environment, ... said Pete Gurt ’85, president of MHS. “He is ...
(Date:5/4/2015)... 2015 Getting patients to work with ... is critical to achieving the “triple aim” of better ... this will require a shift in thinking from stakeholders ... health systems move beyond their traditional boundaries to reach ... the third live meeting of the ACO and ...
(Date:5/4/2015)... NJ (PRWEB) May 04, 2015 The ... organization devoted exclusively to funding innovative lymphoma research and ... education programs, outreach initiatives and patient services – is ... the historic Mayfair Farms in West Orange, NJ on ... nearly $500,000 for innovative research programs through LRF. , ...
Breaking Medicine News(10 mins):Health News:North America Probiotic Market to Increase by 2019, Announces MicroMarketMonitor in Its New Research Report Recently Published at MarketPublishers.com 2Health News:Frequent Nosebleeds Can Be a Sign of a Rare Undiagnosed Disease - Cure HHT 2Health News:Frequent Nosebleeds Can Be a Sign of a Rare Undiagnosed Disease - Cure HHT 3Health News:Milton Hershey School Names 2015 Alumnus of the Year 2Health News:AJMC’s ACO Coalition Explores the New Rules of Patient Engagement 2Health News:AJMC’s ACO Coalition Explores the New Rules of Patient Engagement 3Health News:AJMC’s ACO Coalition Explores the New Rules of Patient Engagement 4Health News:Lymphoma Research Foundation Set to Host Annual Ace Lymphoma Luncheon at Mayfair Farms in West Orange, NJ 2
... President of India wants the Government and people to ... and organ donation. In India., ,Inaugurating the blood ... Vice President asked the government and people to work in ... blood and organs must be encouraged to save precious lives, ...
... Researchers have found that physical inactivity due to lack ... surrounding area make rural people obese.// ,The study ... link between obesity and the environmental factors within rural ... of Public Health research that examines the environmental features ...
... Obesity in Britain is reaching dangerous proportions, and now ... pangs, might turn out to be just what the ... next big thing in health circles. Accomplia, as the ... brain inactive, and might stop the cravings in their ...
... some progress has been taken to improve the oral ... be investigated - Researchers team reported// in an international ... countries including Australia, China, Finland, Ireland, Japan, Kuwait, Scotland, ... International Association for Dental Research that more work were ...
... 26 issue of Archives of Internal Medicine, which is one ... hot flashes// may have more chronic sleep problems than women ... 85% of women in menopause experience hot flashes, heightened sensations ... explained that hot flashes often occur during the night and ...
... the habit, they may gain about 20 pounds, according to ... commonly cited 5 pounds// to 15 pounds. ,The ... activity counseling along with smoking cessation programs, say study authors ... of the University of California, Berkeley. ,The authors ...
Cached Medicine News:Health News:Environmental Factors Leads to Obesity in Rural Communities 2Health News:Unhealthy Oral Habits among Teenagers – Reported Dental Health Authoritie 2Health News:Women With Severe Hot Flashes May Have Increased Chronic Sleep Problem 2Health News:Smokers are Prone to Weight Gain After Quitting 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: