Navigation Links
Synvista Therapeutics Announces First Dosing of SYI-2074 in Clinical Trial for Psoriasis
Date:12/15/2008

pathway that can be inhibited by SYI-2074.

About Psoriasis

Psoriasis is an immune-mediated chronic inflammatory disease usually characterized by red lesions or silvery white scales on the skin, which usually occur on the scalp, knees, elbows, the abdomen (around the navel) and the genitals. In about a quarter of the cases, psoriasis can lead to psoriatic arthritis, another inflammatory disease affecting the joints.

While the exact cause of the disease is unknown, it is believed that both genetic and hormonal factors play a role. It is also known that the TNF-alpha pathway plays a role in the progression of the disease. Other companies have successfully developed drugs that also interfere with TNF-alpha signaling, but these similar drugs are given as injections and are indicated for more severe forms of the disease. Synvista intends to differentiate SYI-2074 by developing a topical formulation of the drug for the treatment of mild-to-moderate psoriasis.

About Synvista Therapeutics

Synvista Therapeutics is a biopharmaceutical company developing diagnostics and drugs to diagnose, treat and prevent cardiovascular disease in people with diabetes. The Company has developed a clinical laboratory test that identifies diabetic patients with the Haptoglobin genotype Hp2-2. The genetic or protein form of this test can be used to identify diabetic patients at high risk for cardiovascular complications. These patients may benefit from a particular formulation of vitamin E. The Company is also developing a test kit to measure CML (carboxy-methyllysine), another potential cardiovascular risk marker.

Synvista Therapeutics is developing oral antioxidant drugs to treat the HDL dysfunction seen in Hp2-2 diabetes, a disease affecting almost 7 million patients in the United States. The Company is also developing alagebrium, a proposed breaker of advanced glyca
'/>"/>

SOURCE Synvista Therapeutics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Data Confirm Synvista Therapeutics Haptoglobin Diagnostic Test Kit Success in Rapidly Determining Cardiovascular Risk in Patients with Diabetes
2. Synvista Therapeutics Reports Results of Three Phase 2 Clinical Trials of SYI-2074 in Diabetic Patients with Cardiovascular Disease
3. Synvista Therapeutics Presents New Preclinical Data Demonstrating the Value of Haptoglobin Genotype Testing In Diabetes at ACC Scientific Sessions
4. Synvista Therapeutics Announces Initiation of Phase 2 Study With Alagebrium for Chronic Heart Failure
5. Synvista Announces New Data Showing Haptoglobin Type Predicts Effectiveness of Tight Glycemic Control on Cardiovascular Outcomes in Patients with Diabetes
6. Synvista Collaboration Demonstrates in Preclinical Studies the Mechanism for Defective Cholesterol Transport in Patients with Diabetes
7. Synvista Therapeutics Highlights New Data Demonstrating the Clinical Benefit of Vitamin E Therapy in Patients Identified on the Basis of Haptoglobin Phenotype Testing
8. Synvista Therapeutics Alagebrium Shows Potential for use in Treating Diabetes-Related Gastrointestinal Complications
9. Halozyme Therapeutics Begins Phase 1 Clinical Trial of Bisphosphonate Administered With rHuPH20 Enzyme
10. Halozyme Therapeutics Announces Roche Begins Phase 1 Clinical Trial and Selects Fourth Exclusive Biologic Target
11. Orexigen(R) Therapeutics Announces Changes to Its Clinical Programs and Management Team
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2014)... 20, 2014 /CNW/ - The issue: Mylan Pharmaceuticals ULC Canada, ... of its Mylan-Nitro Spray 0.4 mg/metered dose due to the ... pump component. A missing "dip tube" could ... the patient. This defect may lead patients to believe they ... to access it. Not receiving nitroglycerin could place them at ...
(Date:9/19/2014)... , Sept. 19, 2014 Medical science ... relationships with key opinion leaders (KOLs) who can ... Despite the critical nature of the MSL function, ... including altering the landscape for creating and maintaining ... to research, the oversight responsibility for the MSL ...
(Date:9/19/2014)... NEW YORK , Sept. 19, 2014 ... claims against the board of directors of PDL BioPharma, ... ) concerning whether the board has breached its fiduciary ... On September 16, 2014, the Company disclosed: ... its independent registered accounting firm, Ernst & Young LLP ...
Breaking Medicine Technology:Advisory - Mylan Pharmaceuticals recalling nitroglycerin spray due to defective pump 2Role of Medical Science Liaisons Shifting in Healthcare Industry 2Harwood Feffer LLP Announces Investigation of PDL BioPharma, Inc. 2
... Ill. , July 22 Sysmex America, Inc., ... information systems, today announced a partnership agreement with Medica Corporation ... to laboratories in North America , Mexico , ... Columbia . Sysmex America will be responsible for instrument ...
... Caraco Pharmaceutical Laboratories, Ltd. (NYSE Amex: ... capsules. This product was recently approved by the ... Pharma,s Abbreviated New Drug Application (ANDA). These tamsulosin ... 0.4 mg from Boehringer Ingelheim Pharmaceuticals, Inc. Tamsulosin ...
Cached Medicine Technology:Sysmex America and Medica Corporation Announce Distribution Partnership 2Sysmex America and Medica Corporation Announce Distribution Partnership 3Caraco Pharmaceutical Laboratories, Ltd. Markets Generic Flomax® 2
(Date:9/20/2014)... (PRWEB) September 20, 2014 Villa del ... resort did not experience any damage in relation to ... and activities available. , Hurricane Odile struck Cabo San ... wind, rain and powerful surf conditions. Located on the ... Islands of Loreto experienced some heavy rain, but no ...
(Date:9/20/2014)... September 21, 2014 Increases in ... to greater waste treatment volumes. However, government regulations ... waste from landfill. According to IBISWorld industry analyst ... implemented strategies aimed at reducing the volume of ... recycled and recovered.” Still, a large proportion of ...
(Date:9/20/2014)... 2014 Ticket Down is a ... This popular ticket exchange is offering their customer appreciation ... 2015 schedule of tours is beginning to fill up. Many ... plans to hit the road, including 21-year-old pop superstar, Ariana ... “Honeymoon Tour,” which will take her to 25 cities across ...
(Date:9/20/2014)... Ticket Down is a reputable ... This popular ticket exchange is offering their customer appreciation promo ... that next step in the entertainment business. The 21-year-old from ... music and entertainment business, but is closing in on “Pop ... 1 album, will hit the road next year on the ...
(Date:9/20/2014)... CA (PRWEB) September 20, 2014 On ... receive a $250,000 pediatric cancer research grant from Hyundai ... Loma Linda University Children’s Hospital located on 11234 Anderson ... work of Dr. Kimberley Payne, Associate Professor at Loma ... work focuses on leukemia in children. , ...
Breaking Medicine News(10 mins):Health News:Villa del Palmar at the Islands of Loreto Fully Functioning After Hurricane 2Health News:Villa del Palmar at the Islands of Loreto Fully Functioning After Hurricane 3Health News:Waste Treatment and Disposal Services in Australia Industry Market Research Report Now Updated by IBISWorld 2Health News:Waste Treatment and Disposal Services in Australia Industry Market Research Report Now Updated by IBISWorld 3Health News:Ariana Grande Tickets in Phoenix, Los Angeles, Anaheim, San Jose, Seattle, and Vancouver Go on Sale Today 2Health News:Ariana Grande Tickets in Phoenix, Los Angeles, Anaheim, San Jose, Seattle, and Vancouver Go on Sale Today 3Health News:Ariana Grande Tickets in Chicago/Rosemont, Kansas City, Milwaukee, Saint Paul, Dallas, Houston, San Antonio, Oklahoma City Go On Sale Today 2Health News:Ariana Grande Tickets in Chicago/Rosemont, Kansas City, Milwaukee, Saint Paul, Dallas, Houston, San Antonio, Oklahoma City Go On Sale Today 3Health News:Loma Linda University Medical Center Receives $250,000 Research Grant From Hyundai Hope On Wheels In Honor Of National Childhood Cancer Awareness Month 2Health News:Loma Linda University Medical Center Receives $250,000 Research Grant From Hyundai Hope On Wheels In Honor Of National Childhood Cancer Awareness Month 3
... Even when treated with hormone therapy to suppress ... their prostate cancer worsening, researchers at Duke University Medical ... American Urological Association annual meeting Sunday (May 15, 2011), ... has generated research interest in recent years as the ...
... May 14 (HealthDay News) -- There appears to be a ... exposed to the herbicide in Vietnam, a new study suggests. ... La. examined the records of 297 patients diagnosed with kidney ... 39 to 63 when they were diagnosed, said they had ...
... Continuous positive airway pressure, or CPAP, can increase ... of obstructive sleep apnea (OSA), even if their symptoms ... in Europe. Patients enrolled in the study reported an ... CPAP treatment. The study will be presented at ...
... airway pressure (CPAP) effectively decreases the risk of cardiovascular ... apnea (OSA), according to a study conducted by researchers ... to assess the impact of OSA and the effectiveness ... The findings will be presented at the ATS ...
... Hospital patients with pneumonia may be at risk ... no warning signs, according to research from the University ... American Heart Association,s Get with the Guidelines project. ... the American Thoracic Society,s 2011 International Conference in Denver. ...
... News) -- A program to boost heart health in students at ... expanded to about 20 middle schools in the state, researchers say. ... to: Eat more fruits and vegetables , Eat ... 150 minutes of physical activity a week , Spend less time ...
Cached Medicine News:Health News:Obesity linked to higher risk of prostate cancer progression 2Health News:Agent Orange Linked to Kidney Cancer: Study 2Health News:CPAP improves daytime sleepiness even in patients with low levels of symptoms 2Health News:CPAP decreases cardiovascular mortality in elderly patients 2Health News:CPAP decreases cardiovascular mortality in elderly patients 3Health News:Pneumonia patients at risk for in-hospital cardiac arrest 2Health News:Teaching Kids to Make Healthier Choices May Pay Off 2
Silver Aluminum finish, full view tempered bent glass sides and door 2 sliding glass doors with push bottom lock and 4 adjustable shelves. Pearwood MDF roof and base. Roof with 3 50 watt recessed hal...
Two sided, 72 frame, acrylic eyewear tower with side mirrors and sign holder on top. Breaks down for easy shipping....
1 Frame clear base post with transparent Eyevee 2.0 Clip....
Omni labs carries an extensive line of frames, lenses, soft contacts, RGP lenses, and many other products and services. It supports Zeiss, American optical, Sola, Rodenstock, Zylowear, Eyewear design...
Medicine Products: