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Synthetic Biologics Reports First Quarter 2013 Financial Results
Date:5/15/2013

ROCKVILLE, Md., May 15, 2013 /PRNewswire/ -- Synthetic Biologics, Inc. (NYSE MKT: SYN), a developer of biologics focused on the prevention and treatment of serious infectious diseases, today reported financial results for the three months ended March 31, 2013 and summarized operational highlights.

Operational HighlightsEmphasis on C. difficile (C. diff) Infection Prevention (SYN-004)

  • In the U.S. each year, 24 million patients are administered IV antibiotics[1] which may be excreted into the gastrointestinal (GI) tract where they can upset the natural balance of the microbiome allowing for the overgrowth of C. difficile which causes diarrhea, colitis and may result in death.
  • SYN-004 is being developed as an oral enzyme product to be co-administered with IV beta-lactam antibiotics. SYN-004 is expected to:
  • Remain in the GI tract to degrade certain beta-lactam antibiotics
  • Protect the healthy microflora from the overgrowth of C. diff
  • In 2012, over 13 million patients were treated with IV beta-lactam antibiotics that may be covered by SYN-004.[1]
  • Phase I and II studies of over 200 subjects treated with 1st generation candidate demonstrated safety, tolerability, and preservation of the normal GI microflora when co-administered with certain penicillins.
  • Infectious Disease Specialist Joins Scientific Advisory Board

  • Brad Spellberg , M.D., is an Associate Professor of Medicine, David Geffen School of Medicine in the Division of General Internal Medicine at Harbor-UCLA Medical Center, and Associate Program Director for Internal Medicine Residency Training Program, Harbor-UCLA Medical Center and LA BioMed.
  • Dr. Spellberg has worked closely with the Infectious Diseases Society of America (IDSA) to focus attention on the rising public health
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  • SOURCE Synthetic Biologics, Inc.
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