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Synthetic Biologics' Academic Collaborator to Present Novel Monoclonal Antibody Combination for Treating Whooping Cough (Pertussis) at Gordon Research Conference
Date:7/21/2014

e SYN-005 antibody combination.

In April 2014, Synthetic Biologics reported positive preclinical results from non-human primate, Pertussis studies of SYN-005, which were associated with favorable decreases in white blood cell counts within two days of treatment and the achievement of nearly normal levels within one week.

"We are pleased to have Dr. Maynard share the research and strong body of evidence supporting the clinical development of SYN-005," stated Jeffrey Riley, Chief Executive Officer of Synthetic Biologics. "Based on the positive non-human primate and murine model findings, Synthetic Biologics has begun manufacturing SYN-005, and remains on track to file an IND to support a Phase I clinical trial expected to initiate during the first half of 2015. In addition, we have submitted an Orphan Drug designation request for SYN-005 for the treatment of Pertussis."

About Synthetic Biologics, Inc.

Synthetic Biologics, Inc. (NYSE MKT: SYN) is a biotechnology company focused on the development of novel anti-infective biologic and drug candidates targeting specific pathogens that cause serious infections and diseases. The Company is developing an oral biologic to protect the gastrointestinal microflora from the effects of IV antibiotics for the prevention of Clostridium difficile (C. difficile) infection, an oral treatment to reduce the impact of methane producing organisms on constipation-predominant irritable bowel syndrome (C-IBS), a series of monoclonal antibodies for the treatment of Pertussis and Acinetobacter infections, and a biologic targeted at the prevention and treatment of a root cause of a subset of IBS. In addition, the Company is developing an oral estriol drug for the treatment of relapsing-remitting multiple sclerosis (MS) and cognitive dysfunction in MS. For more information, please visit Synthetic Biologics' website at www.synthetic
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SOURCE Synthetic Biologics, Inc.
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