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Synergy Pharmaceuticals to Present Scientific Posters at the Upcoming Gastroenterology Society Meetings in the U.S. and Europe
Date:7/31/2012

NEW YORK, July 31, 2012 /PRNewswire/ -- Synergy Pharmaceuticals Inc. (Nasdaq: SGYP), a developer of new drugs to treat gastrointestinal disorders and diseases, announced today that poster presentations on plecanatide that will be given at three separate Gastroenterology society meetings this fall.

Plecanatide is currently being developed for the treatment of patients suffering with chronic constipation (CIC) and irritable bowel syndrome-constipation predominant (IBS-C). Plecanatide is an agonist of the guanylate cyclase-C receptor and is the superior analog of the natriuretic peptide, uroguanylin, the physiologic ligand of GC-C.

The scheduled locations, dates, titles and timing of the presentations are:

JOINT INTERNATIONAL NEUROGASTROENTEROLOGY AND MOTILITY MEETING to be held September 6-8, 2012 in Bologna, Italy

Plecanatide, a Superior Analog of Uroguanylin, as an Oral Drug Candidate for Treatment of Gastrointestinal Functional Disorders and Diseases. (P330) Authored by Andrea Brancale, Gary Jacob and Kunwar Shailubhai. [Poster presentation 8 September 2012]

UNITED EUROPEAN GASTROENTEROLOGY WEEK to be held October 20-24, 2012 in Amsterdam, The Netherlands

Orally Administered Plecanatide, A Guanylate Cyclase-C Agonist, Acts in the Proximal Intestine to Stimulate Fluid Secretion to Normalize Bowel Movement. (P1003) Authored by Stephen Comiskey, John Foss and Kunwar Shailubhai. [Poster presentation date to be announced]

AMERICAN COLLEGE OF GASTROENTEROLOGY ANNUAL MEETING to be held October 19-24, 2012 in Las Vegas, NV

Orally Administered Plecanatide, A Guanylate Cyclase-C Agonist, Acts in the Lumen of the Proximal Intestine to Facilitate Normal Bowel Movement in Mice and Monkeys. (P451) Authored by Stephen Comiskey, John Foss, Gary Jacob, Kunwar Shailubhai. [Poster presentation 21 October 2012]

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