Navigation Links
Syndax Pharmaceuticals Announces Entinostat Data from Two Lung Cancer Clinical Trials at Upcoming World Lung Conference
Date:6/27/2011

nts with advanced NSCLC and elevated levels of tumor e-cadherin at the time of initial diagnosis seemed to do better when treated with erlotinib and entinostat than those treated with erlotinib alone," said Fred R. Hirsch, M.D., Ph.D., Professor of Medicine and Pathology, University of Colorado Health Sciences Center.  "Increasingly we are seeing the importance of biomarkers in predicting patient outcomes in lung cancer.  Patients with tumors with elevated e-cadherin levels represent about 40 percent of the population, demonstrating e-cadherin is a potentially relevant clinical biomarker to select patients for treatment with erlotinib plus entinostat."The following poster and oral presentation on the entinostat and erlotinib combination will be presented Wednesday, July 6 at the World Conference on Lung Cancer:Title:

Analysis of cross-over portion of ENCORE-401, a randomized, double-blind, placebo-controlled phase 2 study of erlotinib with and without entinostat, a class 1 isoform selective histone deacetylase inhibitor (HDAC) in patients with advanced non-small cell lung cancerTime:

12:15 PM – 2:15 PMSession info:

P3.220 Room:

Exhibition HallTitle:

Biomarker analysis of a randomized, double-blind, placebo-controlled phase 2 study of erlotinib with and without entinostat, a class 1 isoform selective histone deacetylase inhibitor (HDAC) in patients with advanced non-small cell lung cancer (NSCLC; ENCORE-401)Time:

2:30 PM - 4:00 PM*Session info:

Mini Oral Session, MO15.04 Room:

G104* This presentation also will be the subject of an e-poster on the same day from 12:15 to 2:15.  Entinostat and 5-Azacitidine (Vidaza®) Syndax and the National Cancer Institute (NCI) are using a dual epigenetic therapy approach to treating advanced lung cancer.   It has been shown that epigenetic gene silencing mediated by DNA methylation and histone deaceylation is a key contr
'/>"/>

SOURCE Syndax Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Syndax Pharmaceuticals Elects Arlene Morris to Board of Directors
2. Syndax Pharmaceuticals Announces Issuance of US Patent for Entinostat
3. Syndax Pharmaceuticals Announces Entinostat Data at 102nd Annual American Association for Cancer Research Meeting
4. Syndax Announces Start of NCI Sponsored Phase 2 Study of Entinostat in Combination in Triple Negative Breast Cancer
5. Syndax Announces Publication of Entinostat NSCLC Data in Cancer Research
6. Syndax Pharmaceuticals to Present at Biotech Showcase 2011
7. Syndax Pharmaceuticals Entinostat in Combination Shows Activity in Breast Cancer
8. Syndax Pharmaceuticals Entinostat Plus Erlotinib Improves Survival in Select NSCLC Patients
9. Syndax Pharmaceuticals Announces Issuance of UK Patent for Entinostat
10. Syndax Pharmaceuticals to Present at Sachs Biotech in Europe Investor Forum
11. Syndax Pharmaceuticals Entinostat Shows Clinical Promise in Patients with Advanced Hormone Refractory Breast Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... YORK , Aug. 28, 2014 ... new market research report is available ... Therapeutics to 2020 - Broadened Diagnostic ... Drive Market Growth despite Patent Expirations ... ADHD Therapeutics to 2020 ...
(Date:8/28/2014)... Ohio , Aug. 28, 2014  A ... competition in generics are adding pressure to pharmaceutical, ... resources. Company resources continue to shrink and approval ... This has led companies to look for additional ... commercialization and for keeping approved products on the ...
(Date:8/28/2014)... 28. August 2014 Sequent ... der Patientenrekrutierung für eine IDE-Pivot-Studie („IDE" ... Beurteilung der Sicherheit und Wirksamkeit des ... („WEB") bekanntgegeben. Adam Arthur, MD, Dozent an ... Neurosurgery/Semmes-Murphey Clinic, und Hauptprüfarzt der WEB-IT-Studie, ...
Breaking Medicine Technology:ADHD Therapeutics to 2020 - Broadened Diagnostic Criteria and Growing Adult Prevalence to Drive Market Growth despite Patent Expirations 2ADHD Therapeutics to 2020 - Broadened Diagnostic Criteria and Growing Adult Prevalence to Drive Market Growth despite Patent Expirations 3ADHD Therapeutics to 2020 - Broadened Diagnostic Criteria and Growing Adult Prevalence to Drive Market Growth despite Patent Expirations 4ADHD Therapeutics to 2020 - Broadened Diagnostic Criteria and Growing Adult Prevalence to Drive Market Growth despite Patent Expirations 5ADHD Therapeutics to 2020 - Broadened Diagnostic Criteria and Growing Adult Prevalence to Drive Market Growth despite Patent Expirations 6ADHD Therapeutics to 2020 - Broadened Diagnostic Criteria and Growing Adult Prevalence to Drive Market Growth despite Patent Expirations 7ADHD Therapeutics to 2020 - Broadened Diagnostic Criteria and Growing Adult Prevalence to Drive Market Growth despite Patent Expirations 84 Key Factors to Consider When Choosing an Effective Regulatory Outsourcing Partner 24 Key Factors to Consider When Choosing an Effective Regulatory Outsourcing Partner 34 Key Factors to Consider When Choosing an Effective Regulatory Outsourcing Partner 4Sequent Medical kündigt Start einer IDE-Studie für das WEB System zur Embolisation von Aneurysmen bekannt 2Sequent Medical kündigt Start einer IDE-Studie für das WEB System zur Embolisation von Aneurysmen bekannt 3
... European Association for the Study of ... Diabetes Annual Meeting, ... Annual Meeting of the European Association for the Study,of Diabetes demonstrate ... cardiovascular disease in patients with type 2,diabetes. ACTOS is an oral ...
... Therapy, ALEXANDRIA, La., Sept. 18 Life ... NJ, an emerging provider of,groundbreaking medical devices for ... ThermoSuit(R) System has been granted European CE,Mark (Conformite ... indicated, e.g., to induce hypothermia in patients to,preserve ...
Cached Medicine Technology:ACTOS(R) (pioglitazone HCl) Demonstrates Reduced Risk of Ischemic Cardiovascular Disease in Patients with Type 2 Diabetes 2ACTOS(R) (pioglitazone HCl) Demonstrates Reduced Risk of Ischemic Cardiovascular Disease in Patients with Type 2 Diabetes 3Life Recovery Systems Receives European CE Mark Approval for Its ThermoSuit(R) System 2
(Date:8/28/2014)... August 28, 2014 Millennium Treatment ... throughout September. This month will be a celebration ... mental health services. Along with other treatment facilities ... helping to spread the word about this national ... honoring the work of treatment and recovery professionals, ...
(Date:8/28/2014)... Nashville, TN (PRWEB) August 28, 2014 ... the insurance industry on the Internet will now have ... Quotes Pros company. In one click this year, some ... presented at http://quotespros.com/life-insurance.html . , The promoted ... the Quotes Pros finder tool represent popular policies. The ...
(Date:8/28/2014)... ABC television stars will join forces this Labor ... Telethon airing Sunday, Aug. 31, 9/8c on ABC television ... awareness to help save and improve the lives of ... tuning into the 2014 telethon to benefit the Muscular ... some of the network’s leading stars, including Alyssa Milano ...
(Date:8/28/2014)... Pittsburgh, PA (PRWEB) August 28, 2014 ... Ready Nutrition announced today a regional partnership designed ... and goal planning for competitive young athletes, scholastic ... , “Our partnership’s Strong Body & Mind Initiative ... that addresses both the physical and mental dynamics ...
(Date:8/28/2014)... San Mateo, CA (PRWEB) August 28, 2014 ... announce that the MRI Technology program is re-accredited for ... Registry of Magnetic Resonance Imaging Technologists (ARMRIT). , ... re-accreditation. We are constantly improving our program to make ... There is a lot of interest in MRI field ...
Breaking Medicine News(10 mins):Health News:Millennium Treatment Group Celebrates National Recovery Month 2Health News:Best Life Insurance Rates for 2014 Now Promoted at Insurer Website 2Health News:ABC Stars Unite to Fight Back Against Muscle Disease During MDA Show of Strength Telethon 2Health News:ABC Stars Unite to Fight Back Against Muscle Disease During MDA Show of Strength Telethon 3Health News:ABC Stars Unite to Fight Back Against Muscle Disease During MDA Show of Strength Telethon 4Health News:Allegheny Health Network and Come Ready Nutrition Announce Regional Partnership 2Health News:Allegheny Health Network and Come Ready Nutrition Announce Regional Partnership 3Health News:Allegheny Health Network and Come Ready Nutrition Announce Regional Partnership 4Health News:Gurnick Academy’s MRI Program Is Re-Accredited by ARMRIT for the 5 Years 2
... major league pitcher , FRIDAY, Oct. 30 (HealthDay News) -- ... than a second, it curves and then drops, baffling the ... correctly, is one of baseball,s most daunting pitches. For more ... sworn that the ball seems to have a life of ...
... Partnership to scale ... ... for AIDS Relief (PEPFAR), the largest commitment ever by any nation to combat a single ... Ambassador Eric Goosby, U.S. Global AIDS Coordinator, who oversees implementation of PEPFAR , in ...
... Oct. 30 NovaBay Pharmaceuticals, Inc. (NYSE-Amex: NBY ... antifungal activity in an established pre-clinical infected nail model ... at the 47th Annual Meeting of the Infectious Diseases ... tests both the penetration of the nail as well ...
... 2009 Shire plc (LSE: SHP, NASDAQ: SHPGY), the ... INTUNIV (guanfacine) Extended Release Tablets, at a major psychiatric ... study was to assess the change from baseline on ... Long Form (CPRS-R:L) in patients ages 6 to ...
... ,Charles Drew University has ... the university,s long-term, UCLA partnership aimed at reducing the risk of ... The National Institutes of Health, the National Cancer Institute and the ... Cancer Center Partnership. An additional $4.5 million was allocated to ...
... ... Kentucky felt his heart racing after playing Millsaps College homecoming game on Saturday, October 24, ... Jackson, MS (Vocus) ... his heart racing after playing Millsaps College homecoming game on Saturday, October 24, 2009. , ...
Cached Medicine News:Health News:Scientist Throws Curve Into Breaking-Ball Debate 2Health News:Scientist Throws Curve Into Breaking-Ball Debate 3Health News:U.S. President's Emergency Plan for AIDS Relief Joins mHealth Alliance 2Health News:U.S. President's Emergency Plan for AIDS Relief Joins mHealth Alliance 3Health News:NovaBay's Aganocides Show Penetration and Efficacy in a Pre-Clinical Infected Human Nail Model of Onychomycosis 2Health News:NovaBay's Aganocides Show Penetration and Efficacy in a Pre-Clinical Infected Human Nail Model of Onychomycosis 3Health News:NovaBay's Aganocides Show Penetration and Efficacy in a Pre-Clinical Infected Human Nail Model of Onychomycosis 4Health News:INTUNIV demonstrated symptom reduction on oppositional subscale Conners' ADHD rating scale 2Health News:INTUNIV demonstrated symptom reduction on oppositional subscale Conners' ADHD rating scale 3Health News:Charles Drew University awarded $9.8 million 2Health News:College Middle Line Backer Treated for Wolff Parkinson White Syndrome at Baptist Cardiovascular Services 2Health News:College Middle Line Backer Treated for Wolff Parkinson White Syndrome at Baptist Cardiovascular Services 3
... St. Jude Medical offers the world's ... Pacel bipolar pacing catheters are available in ... a broad range of curve choices and ... Pacing Catheter is indicated for use in ...
Automated slide maker and stainer...
... treadmill has streamlined design, "whisper ... brushless DC motor and direct ... system that operates on standard ... smooth operation, remarkably low motor ...
... Series 2000 Treadmill is advanced in ... The extra-long, 60-inch treadmill surface provides ... patients. The Series 2000 Treadmill ... accommodate severely debilitated patients. Its extremely ...
Medicine Products: