Navigation Links
Sustained Viral Response from Phase 2 Studies of BI 201335, Including Difficult-to-Treat HCV Patient Types
Date:11/8/2011

SAN FRANCISCO and RIDGEFIELD, Conn., Nov. 8, 2011 /PRNewswire/ -- Boehringer Ingelheim Pharmaceuticals, Inc. today announced results from two Phase 2 studies evaluating the combination of the company's protease inhibitor, BI 201335, with pegylated interferon (PegIFN) and ribavirin (RBV) in treatment-naive genotype-1 (GT1) hepatitis C virus (HCV) patients.  The results from the SILEN-C3 and SILEN-C1 studies show that BI 201335 may have the potential to shorten the duration of treatment compared to PegIFN/RBV for a large portion of patients, as well as improve the likelihood of viral cure for patients with characteristics that make their HCV more difficult to treat.  These data were presented in oral sessions at the American Association for the Study of Liver Diseases (AASLD) 2011 Liver Meeting in San Francisco, CA.  Phase 3 studies evaluating BI 201335 in various regimens and patient types are ongoing.

"Shortening the length of treatment is among the goals we have at Boehringer Ingelheim as we seek to innovate a new treatment option for HCV patients.  We are encouraged to see that the SILEN-C3 study results suggest that treatment with BI 201335 beyond 12 weeks may not be needed for treatment-naive patients who had an extended rapid viral response," said Peter Piliero, M.D., Vice President, Clinical Development and Medical Affairs, Boehringer Ingelheim Pharmaceuticals, Inc.  "The SILEN-C1 subgroup results from the more difficult-to-treat patient types also are promising.  We look forward to results from our ongoing Phase 3 program with BI 201335."

(Abstract #36) SILEN-C3:  Treatment for 12 or 24 Weeks with BI 201335 Combined with Peginterferon Alfa-2a and Ribavirin (P/R) in Treatment-Naive Patients with Chronic Genotype-1 HCV Infection

The results from SILEN-C3 indicate that among patients who had an extended rapid viral response (eRVR), 12 weeks of treatment with
'/>"/>

SOURCE Boehringer Ingelheim Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. New Study Presented at WorldSleep 2007 Demonstrates Ramelteon Has Sustained Efficacy Over Six Months in Adults With Chronic Insomnia
2. Cypher(R) Sirolimus-Eluting Coronary Stent Demonstrates Sustained Clinical Benefits Compared to Bare Metal Stents in Five-Year Randomized Clinical Trial With No Differences in Long-Term Safety
3. Lotus Pharmaceuticals, Inc. Achieves Significant Milestones in the Development of Isosorbide Mononitrate Sustained Release Tablets
4. FTY720, a novel oral therapy in development for MS, shows sustained benefits for the majority of patients after three years of treatment
5. CERVARIX(R) Shown to Provide Longest Duration of Sustained Neutralizing Antibodies to Date
6. After One Year, Type 2 Diabetes Patients Taking Exenatide Once Weekly Sustained Improvements in Glycemic Control and Weight; DURATION-1 Presented at ADA 2008
7. Schering-Plough Announces Phase III Data for Sustained Follicle Stimulant
8. Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III Melanoma Demonstrated Significant and Sustained Impact on Relapse-Free Survival
9. FDA Updates Label for AVANDIA(R) to Include Clinical Findings Demonstrating Sustained Glycemic Control for Up to Five Years
10. Top-Line Results of Boceprevir Phase II Study Showed High Rate of Sustained Response (SVR) in Genotype 1 Treatment-Naive Hepatitis C Patients
11. Spherics, Inc. Offers Extended Release Formulation for Sustained and Stable Levodopa Levels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... -- Wrightington, Wigan and Leigh NHS ... ) are delighted to announce WWL,s decision to implement ... system. The system will be implemented across all three ... delivers healthcare in the future. WWL ... and on-budget system implementations as well as its proven ...
(Date:9/30/2014)... ROCKVILLE, Md. , Sept. 30, 2014 /PRNewswire/ ... natural way to modernize medicine, announced today the ... line of nutraceuticals developed to address men and ... staying healthy and vibrant into old age while ... line includes three condition-specific, whole-food and herb-based formulas, ...
(Date:9/30/2014)... Sept. 30, 2014 Arbor Pharmaceuticals, LLC. ... Global Markets Direct,s, ,Arbor Pharmaceuticals, LLC. - ... of the Arbor Pharmaceuticals, LLC.,s pharmaceutical research and ... on the current therapeutic developmental pipeline of Arbor ... stages, therapeutics assessment by drug target, mechanism of ...
Breaking Medicine Technology:Wrightington, Wigan and Leigh NHS Foundation Trust selects Allscripts Sunrise 2Wrightington, Wigan and Leigh NHS Foundation Trust selects Allscripts Sunrise 3Wrightington, Wigan and Leigh NHS Foundation Trust selects Allscripts Sunrise 4Arbor Pharmaceuticals, LLC. - Product Pipeline Review - 2014 2Arbor Pharmaceuticals, LLC. - Product Pipeline Review - 2014 3
... CENTENNIAL, Colo. , May 4 ... today the winners of the 2010 Graeme Clark Cochlear ... Scholarship is awarded to five high school seniors who,ve ... communities.  All recipients have a Nucleus® cochlear implant and ...
... 4 ISTA Pharmaceuticals, Inc. (Nasdaq: ISTA ), today announced it ... pm Pacific Time on May 12, 2010 , in San ... Lauren Silvernail will provide an update on the Company,s marketed products ... The presentation will ...
Cached Medicine Technology:Cochlear Americas Honors Achievements of Cochlear Implant Recipients during May's Better Hearing & Speech Month 2Cochlear Americas Honors Achievements of Cochlear Implant Recipients during May's Better Hearing & Speech Month 3Cochlear Americas Honors Achievements of Cochlear Implant Recipients during May's Better Hearing & Speech Month 4ISTA Pharmaceuticals to Present at the Ninth Annual JMP Securities Research Conference 2
(Date:10/1/2014)... October 01, 2014 Bedros Keuilian is ... Boot Camp fitness boot camps, he’s also considered the ... , with sold out business summits, a line of ... consultant to a recent Spike TV reality show to ... now is the time for personal trainers and fitness ...
(Date:10/1/2014)... 01, 2014 T.E.N., a ... relationship-marketing firm, announced today the nominees vying ... Project of the Year Awards for North ... organizations in financial services, commercial, health care, ... endeavors that address key issues in the ...
(Date:10/1/2014)... 2014 Beverly Hills licensed Clinical Psychologist ... celebrating 20 years of private practice in her Beverly ... to achieve greater joy and fulfillment in their relationships. ... signs and suggestions for anyone who suspects they are ... “Believe it or not, it’s not always easy to ...
(Date:10/1/2014)... NoteSwift Inc., announced today their new NoteSwift™ 2.0 for ... is the bridge between the EHR and Dragon Medical ... information at the point of care. NoteSwift reduces the ... more than half – and virtually eliminates mouse clicks ... impedes EHR use according to the June 12, 2014 ...
(Date:10/1/2014)... Today in Bahir Dar, Ethiopia, at the occasion ... has gathered some 150 African and international leishmaniasis ... treatment safety and efficacy monitoring plan, carried ... Kenya, Sudan, Uganda, and Ethiopia, were presented to ... access to treatment of kala-azar with the combination ...
Breaking Medicine News(10 mins):Health News:Bedros Keuilian Shares Tips on Selling Personal Training for the Holidays 2Health News:Bedros Keuilian Shares Tips on Selling Personal Training for the Holidays 3Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 2Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 3Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 4Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 5Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 6Health News:T.E.N. Announces Nominees for the 2014 ISE® North America Awards; People’s Choice Award voting now open to industry at large 7Health News:Prominent Beverly Hills Psychologist Dr. Kathleen Mojas Celebrating 20 Years in Private Practice Identifies Common Warning Signs That You May Be In a Toxic Relationship. 2Health News:Prominent Beverly Hills Psychologist Dr. Kathleen Mojas Celebrating 20 Years in Private Practice Identifies Common Warning Signs That You May Be In a Toxic Relationship. 3Health News:NoteSwift Joins Allscripts Developer Program 2Health News:NoteSwift Joins Allscripts Developer Program 3Health News:Results of large-scale roll out of combination treatment for kala-azar in Eastern Africa 2
... 12, 2008 ... , WHO/ WHAT: "Iron Andy" Holder, an Ironman Arizona competitor who was ... this Sunday,s triathlon to encourage others who have chronic ... their condition and to live without limits., ...
... Up to Promote New Appliance Line,s European, Style and Ingenious Features ... ... YORK, April 3, 2008 Known and admired for her,multi-tasking talents as ... Ripa for the North America launch of its new,premium kitchen appliance line ...
... screening, recommended by the Centers for Disease Control, ... critical to preventing still births and serious birth ... study published in the April issue of the ... statistics, when used to determine screening rates, may ...
... gap between stated and unstated feelings about Clinton, ... people feel more "insecure" than they are typically willing,to ... Company. In,addition, the "confidence" voters express about the U.S. ... surface and therefore does not appear to be,very deep., ...
... April 3, 2008 /PRNewswire/ - The GLOBAL ... service for,business executives in pharmaceutical and life ... and other industries,launches a Virtual Tour of ... COUNCIL service by visiting, http://www3.best-in-class.com/gr148.htm or ...
... The International Neuroinformatics Coordinating Facility (INCF) announces further ... the Neuroscience Peer Review Consortium (NPRC) initiative. The ... have agreed to accept manuscript reviews from other ... research articles. Currently, 27 journals have joined the ...
Cached Medicine News:Health News:Ironman Competitor with Diabetes Encourages Others to Live Without Limits; Competes in Ironman Arizona in Tempe 2Health News:Europe's Leading Premium Appliance Brand Taps America's Most Stylish, Multi-Tasking Mom to Launch New Appliance Line in North America 2Health News:Europe's Leading Premium Appliance Brand Taps America's Most Stylish, Multi-Tasking Mom to Launch New Appliance Line in North America 3Health News:Europe's Leading Premium Appliance Brand Taps America's Most Stylish, Multi-Tasking Mom to Launch New Appliance Line in North America 4Health News:Prenatal syphilis screening rates: Are they being accurately reported? 2Health News:Voting for Clinton Evokes Deep-Seated Feelings of Insecurity 2Health News:Global Benchmarking Council Launches New Virtual Tour of Research & Networking Service 2Health News:Neuroscience Peer Review Consortium announces increased journal participation 2
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: