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Surveyed U.S. Neurologists Would Prescribe Biogen Idec's Tecfidera to 20 Percent of Their Patients with Relapsing-Remitting Multiple Sclerosis (RR-MS)
Date:4/8/2013

BURLINGTON, Mass., April 8, 2013 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that surveyed U.S. neurologists indicated that they would prescribe Biogen Idec's Tecfidera to 20 percent of their patients with relapsing-remitting multiple sclerosis (RR-MS). Decision Resources forecasts that Tecfidera will earn a patient share similar to surveyed neurologists' estimate in the U.S. RR-MS market by 2021, owing to its robust efficacy—specifically, a greater reduction in annualized relapse rate (ARR) relative to first-line agents—and a strong safety profile relative to the most effective current therapies, such as Biogen Idec's Tysabri.

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The DecisionBase 2013 report entitled Where Do Physicians and Payers Signal the Greatest Need—and Greatest Opportunity—for New Therapeutic Advances? also finds that, according to insights from surveyed U.S. and European neurologists and managed care organizations' (MCO) pharmacy directors, an increased effect in preventing sustained disability progression is one of the greatest unmet needs in RR-MS. Clinical data and the opinions of interviewed thought leaders indicate that Genzyme/Sanofi/Bayer HealthCare's emerging agent Lemtrada has demonstrated the potential to partially fulfill this unmet need.

Surveyed U.S. MCO pharmacy directors are also particularly receptive to new RR-MS therapies that offer a greater reduction in ARR over currently available therapies.

"We expect that several emerging agents, notably Lemtrada and potentially Roche/Genentech's ocrelizumab, will match the improvements on reduction in ARR that surveyed U.S. payers indica
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SOURCE Decision Resources
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