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Surveyed EU5 Rheumatologists Prescribe Biologics to Approximately Half of Their DMARD-Treated Psoriatic Arthritis Patients
Date:11/14/2013

ted by a lack of comparative data which contributed to Simponi's (Merck) ASMR of V (i.e. no added benefit versus marketed comparators) in France, stringent benefit assessments in Germany and the upcoming requirement for a therapeutic positioning report in Spain that will consider clinical benefit and degree of innovation when evaluating emerging drugs. As the cost constrained EU5 markets strive to draw out value for money, increasingly demanding HTA and increasingly complex pricing and reimbursement negotiations are evident in all markets.

The report also finds that the majority of surveyed rheumatologists expect the earliest reimbursed treatment line for Stelara will be as a second- or third-line therapy for conventional DMARD-refractory patients, and surveyed physicians do not foresee apremilast achieving a more favorable reimbursed treatment line, despite the drug's oral delivery and favorable safety profile.

"By the end of 2016, surveyed physicians across the EU5 report they will more likely position emerging therapies Stelara and apremilast in the third- or later-lines than in earlier lines of therapy for their PsA patients," said Decision Resources Analyst Kathryn Beane. "Surveyed physicians cite multiple reasons, including efficacy and a lack of a postmarketing efficacy and safety record (for apremilast) as factors constraining their prescribing."

About Decision Resources
Decision Resources (www.decisionresources.com) is a world leader in market research publications, advisory services and consulting designed to help clients shape strategy, allocate resources and master their chosen markets. Decision Resources is a Decision Resources Group company.

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