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Surveyed EU5 Rheumatologists Prescribe Biologics to Approximately Half of Their DMARD-Treated Psoriatic Arthritis Patients
Date:11/14/2013

BURLINGTON, Mass., Nov. 14, 2013 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that surveyed rheumatologists across the EU5 (France, Germany, Italy, Spain and the United Kingdom) currently prescribe biologics—largely Pfizer's Enbrel or AbbVie's Humira— to approximately half of their psoriatic arthritis (PsA) patients who are treated with a disease-modifying antirheumatic drug (DMARD). By the end of 2016, 58 to 86 percent of respondents in each EU5 market expect to prescribe the fifth TNF-alpha inhibitor approved for PsA—UCB's Cimzia—compared with 30 to 58 percent who expect to prescribe Janssen's first-in-class IL-12/23 inhibitor Stelara. Notably fewer surveyed physicians expect to prescribe other emerging therapies by this time point, including Celgene's oral phosphodiesterase-4 inhibitor apremilast and Novartis's IL-17 inhibitor secukinumab.

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The European Physician and Payer Forum report entitled Moving Beyond the TNF-Alpha Inhibitor Class in Psoriatic Arthritis in Europe: How Will Payers and Prescribers React to an Expanding Array of Treatment Options? also finds that while a novel mechanism of action may be a pricing lever, given the limited treatment options for TNF-alpha-refractory patients in PsA, manufacturers must strive to show evidence that sets their new brand apart from currently available TNF-alpha inhibitors in order to optimize market access opportunity for emerging brands. The rising health technology assessment (HTA) bar is illustra
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