Navigation Links
Surface Logix Achieves Objectives With SLx-2101 in Phase 2a Clinical Trial in Hypertension
Date:1/8/2008

nge of tissues. SLx-2101 is uniquely positioned among the known PDE5 inhibitors to address cardiovascular disease because, compared to currently marketed PDE5 drugs, SLx-2101 preferentially distributes into cardiovascular tissue. By virtue of its large volume of distribution, SLx-2101 achieves sustained plasma levels and a long duration of action, without showing accumulation upon repeat dosing. This superior product profile allows for daily or on demand dosing with a predictable response in a number of cardiovascular disorders that currently marketed PDE5 therapies cannot adequately address. Surface Logix is also currently conducting a Phase 2a study of SLx-2101 in secondary Raynaud's disease, a vasospastic condition in which PDE5 inhibition has been shown to have a therapeutic benefit. Preclinical data obtained in models of heart failure suggest that SLx-2101 has potential in this indication as well.

About Surface Logix, Inc.

Surface Logix, Inc. uses its expertise in biophysical chemistry to create and develop novel small molecule drugs (NCEs) with superior drug-like properties that are clearly differentiated from competitive products. The company is advancing multiple internal programs focused primarily on cardiovascular, metabolic, oncologic and fibrotic diseases. For more information, please visit http://www.surfacelogix.com.

Contact:

Leland Webster, Ph.D., M.B.A.

Surface Logix, Inc.

Vice President, Corporate Development

617.746.8520

Media:

Sarah Cavanaugh

MacDougall Biomedical Communications Inc.

scavanaugh@macbiocom.com

781-235-3060


'/>"/>
SOURCE Surface Logix, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Surface Logix, Inc. to Present at the Piper Jaffray Health Care Conference
2. Cantel Medical Corp.s Crosstex Subsidiary Addresses School MRSA Concerns With SaniTyze(TM) Brand Hand Sanitizer and Sanitex(R) Surface Disinfecting Line of Products
3. Surface Logix Presents Positive Phase 1 Repeat-Dose Trial Data on SLx-4090 at The 16th International Symposium on Drugs Affecting Lipid Metabolism
4. Keeping the Data Center Clean: ATEN Launches Industry-First KVM Switches with Antimicrobial Nanocoating to Protect Products from Bacteria Surviving on Surfaces
5. Acologix Presents Preclinical Data on Cartilage Regeneration by AC-100 at the OARSI 2007 World Congress on Osteoarthritis
6. Pharmasset Announces R7128 Achieves 85% Rapid Virologic Response in a 4-week Combination Study for the Treatment of Chronic Hepatitis C
7. PLC Systems Achieves Successful Early Conclusion of RenalGuard(TM) Pilot Safety Trial
8. Cethromycin Achieves All Endpoints in Second Pivotal Phase III Trial for Treatment of Pneumonia
9. Avastin Achieves Impressive Rate of Curative Surgery in Patients with Advanced Colorectal Cancer
10. Large Blinded Clinical Study Achieves High Accuracy for the Diagnosis of Melanoma Using In Vivo Confocal Microscopy
11. Trius Initiates U.S. Phase I Trial for its Oxazolidinone Antibacterial Drug, TR-701
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/31/2015)...  Ascendant Solutions, Inc. (Pink Sheets: ASDS ) ... subsidiary, Dougherty,s Holdings, has acquired Springtown Drug (" ... Springtown, Texas , just north of ... pharmacy has provided retail prescriptions, healthcare products and gifts ... . The Springtown ...
(Date:8/31/2015)... Pa. , Aug. 31, 2015 The ... reversed statewide since Pennsylvania State ... life-saving drug kits, naloxone. Heroin and opioid ... Pennsylvania , killing more individuals than ... approximately 2,400 Pennsylvanians died from a drug overdose. ...
(Date:8/31/2015)... Regen BioPharma, Inc. (OTCBB: RGBP) and ... means of delivering its patented (US Patent 8,263,571) ... utilizing a clinically approved formulation as delivery system.  ... gene silencing therapeutics in which the gene silencing ... body.  By utilizing a local delivery system, potential ...
Breaking Medicine Technology:Ascendant Solutions, Inc. Announces Completion of Fifth Pharmacy Acquisition by Its Dougherty's Holdings Subsidiary 2Ascendant Solutions, Inc. Announces Completion of Fifth Pharmacy Acquisition by Its Dougherty's Holdings Subsidiary 3Departments of Drug & Alcohol Programs and Health Announce Report 289 Pennsylvanian Lives Saved by Naloxone 2Departments of Drug & Alcohol Programs and Health Announce Report 289 Pennsylvanian Lives Saved by Naloxone 3Regen BioPharma, Inc. Develops BORIS Gene Silencing Based Treatment for Unresectable Liver Cancer 2Regen BioPharma, Inc. Develops BORIS Gene Silencing Based Treatment for Unresectable Liver Cancer 3
... One of the more difficult aspects of planning ... resource and investment allocations that are needed to prepare ... wrestle with allocating the appropriate resources for informing key ... are carried out across different functional areas. ...
... Floridians turned in nearly 5,500 pounds of prescription and ... enforcement offices throughout the state during the Drug Take ... the amount dropped off at 38 sites last year. ... National Association of Drug Diversion Investigators (NADDI) ...
Cached Medicine Technology:Study Uncovers Key Success Factors and Common Failure Points for Launching New Metabolic Products in Today's Competitive Healthcare Market 2NADDI and the C.A.R.E.S. Alliance Co-Sponsor Successful Drug Take Back Day 2
(Date:8/31/2015)... ... August 31, 2015 , ... ... was formed in 2008, the result of a merger of five of the ... working cooperatively, they could provide more cost-effective and higher quality care than they ...
(Date:8/31/2015)... ... ... Presents, Dr. Michael Betsy! Dr. Betsy has been reviewed and approved as an “NJ ... Don Bosco Prep in 1990 and was Class Salutatorian. He earned Varsity letters in ... year. He was inducted into the National Honor Society as a sophomore, was an ...
(Date:8/31/2015)... Nashville, TN (PRWEB) , ... August 31, 2015 , ... ... and how it may be prevented during Amblyopia Awareness Month. Only a comprehensive eye ... is the most common cause of visual impairment among children, affecting approximately 2 to ...
(Date:8/31/2015)... ... August 31, 2015 , ... Diablo Publications ... that it has officially launched a new website and company identity ( diablopublications.com) ... are more closely aligned with the company’s strategic vision for growth and expansion ...
(Date:8/31/2015)... ... , ... Three Bakers Gluten Free Bakery launched the redesign of its website, ... information on their offering of gluten-free breads and pizzas, living without gluten, and resources ... us to share information about our gluten free product offerings, but also to really ...
Breaking Medicine News(10 mins):Health News:NJ Top Docs Presents, Garden State Urology! 2Health News:NJ Top Docs Presents, Dr. Michael Betsy! 2Health News:NJ Top Docs Presents, Dr. Michael Betsy! 3Health News:Renowned Eye Surgeon Dr. Stewart Shofner Shares Information about the Causes of Lazy Eye During Amblyopia Awareness Month 2Health News:Renowned Eye Surgeon Dr. Stewart Shofner Shares Information about the Causes of Lazy Eye During Amblyopia Awareness Month 3Health News:Diablo Publications Launches New Company Website 2Health News:Diablo Publications Launches New Company Website 3Health News:Three Bakers Gluten Free Bakery Announces Launch of New Website 2
... today reveals that California ranks in the bottom half of ... District of Columbia in the percentage of children who ... "Reading Across the Nation: A Chartbook," prepared by the UCLA ... Reach Out and Read National Center, only 44.6 percent of ...
... published today in a special supplement to the Journal of ... for patients who speak little, if any, English and the ... settings. The studies overall report that measurable disparities in quality ... the same language. , Hospitalized Patients ...
... for Grand Wine Tasting on Friday ... TALLAHASSEE, Fla., Nov. 1 The 12th Annual Tallahassee,Wine ... featuring more than 200 wines from around the world, including,unique ... off at 6 p.m. with three fun-filled sessions about wine:, ...
... is the most common,widespread chronic pain condition in ... But, findings from two new surveys commissioned by,the ... much to be,learned about this debilitating condition. ... half (45%) of respondents,have never heard of fibromyalgia. ...
... Addition to Postal Service Social Awareness Stamp,Series, WASHINGTON, ... next year to help raise awareness about Alzheimer,s disease,as ... John,Potter announced today, on the first day of both ... "With the Alzheimer,s Awareness commemorative stamp, we,ll ask,Americans ...
... 1 NexGenix Pharmaceuticals, a privately,held biotechnology company ... tumor suppressor disorder neurofibromatosis and related sporadic,tumors, today ... of NexGenix will be presenting at the Acumen ... at 3:00 pm on November 5th, 2007,at the ...
Cached Medicine News:Health News:Report shows less than half of kids in California are being read to daily 2Health News:Report shows less than half of kids in California are being read to daily 3Health News:JGIM: studies show importance of language services on disparities, quality of care 2Health News:JGIM: studies show importance of language services on disparities, quality of care 3Health News:JGIM: studies show importance of language services on disparities, quality of care 4Health News:JGIM: studies show importance of language services on disparities, quality of care 5Health News:Take a Culinary Trip Around the World for a Good Cause: March of Dimes 2Health News:Medialink Features: The Painful Truth About Fibromyalgia 2Health News:Alzheimer's Disease to be Highlighted on Stamp Next Year 2Health News:NexGenix Pharmaceuticals to Present at Acumen BioFin Rodman & Renshaw 9th Annual Healthcare Conference 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
Medicine Products: