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Sunesis Pharmaceuticals to Present Non-Clinical Data at the Annual Meeting of the American Association for Cancer Research
Date:4/9/2008

break repair pathways including homologous recombination

Session: Stress Responses

Abstract #1859

8:00 a.m. - 12:00 p.m. Exhibit Hall B-F, San Diego Convention Center

-- Ex vivo activity of SNS-595 against biopsies of acute myeloid leukemia,

triple negative breast and ovarian cancers supports ongoing and

potential clinical indications

Session: Novel Drug Targets, Agents and Mechanisms

Abstract #2830

1:00 p.m. - 5:00 p.m. Exhibit Hall B-F, San Diego Convention Center

Suzanne Trudel, MSc, M.D., Assistant Professor, Princess Margaret Hospital, University Health Network, will provide an oral presentation on SNS-032's preclinical activity in multiple myeloma as part of a minisymposium on Tuesday, April 15, 2008. In addition, translational research data detailing the relationship between SNS-032's mechanism and its activity in certain types of cancer will be presented in a poster. SNS-032, a potent and selective inhibitor of cyclin-dependent kinases 2, 7 and 9, is being evaluated in a Phase 1 clinical trial in patients with relapsed/refractory chronic lymphocytic leukemia or multiple myeloma.

SNS-032 Oral Presentation

Tuesday, April 15, 2008

-- SNS-032, a potent and selective CDK2, 7 and 9 inhibitor, demonstrates

preclinical activity in human multiple myeloma

Minisymposium: Novel Genomic Approaches, Drugs, Targets, and Strategies

Abstract #4972

4:55 p.m. to 5:10 p.m. Room 30A-C, San Diego Convention Center

SNS-032 Poster Presentation

Sunday, April 13, 2008

-- SNS-032, a novel inhibitor of cyclin-dependent kinases 2, 7, and 9,

blocks transcription of cyclin D1 and Mcl-1, causing cell death in

mantle cell lymphoma cell lines

Session: Histone Deacetylase Inhibitors and Cell Cycle Inhibitors

Abstract #756

8:00 a.m. - 12:00 p.m. Exhibit Hall B-F, San Diego Convent
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SOURCE Sunesis Pharmaceuticals, Inc.
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