Sunesis Pharmaceuticals Reports Data from Nonclinical Studies of SNS-032 at the Annual Meeting of the American Association for Cance...( SNS-032 Demonstrates Activity in Mul...),Health

SNS-032 Demonstrates Activity in Multiple Myeloma and Mantle Cell Lymphoma

SOUTH SAN FRANCISCO, Calif., April 16 /PRNewswire-FirstCall/ -- Sunesis Pharmaceuticals, Inc. (Nasdaq: SNSS) today reported data from nonclinical studies of SNS-032 in multiple myeloma and mantle cell lymphoma. Data from studies conducted in collaboration with the Multiple Myeloma Research Consortium (MMRC) and with the University of Texas MD Anderson Cancer Center were presented at the Annual Meeting of the American Association for Cancer Research (AACR) in San Diego, CA. SNS-032, a potent and selective inhibitor of cyclin-dependent kinases (CDKs) 2, 7 and 9, is currently in a Phase 1 clinical trial in patients with chronic lymphocytic leukemia (CLL) or multiple myeloma.

"Our collaborations with leading oncology thought leaders, such as Dr. Trudel and the MMRC Validation Team and Dr. Plunkett of MD Anderson Cancer Center, provide us with important new insights into SNS-032's activity in hematologic cancers," said Daniel C. Adelman, M.D., Senior Vice President, Development and Chief Medical Officer of Sunesis. "Results presented today from studies in primary and human cell lines demonstrate SNS-032's potential both alone and in combination with other agents in multiple myeloma and other B cell malignancies and further support our ongoing Phase 1 clinical trial."

An oral presentation by Suzanne Trudel, MSc, M.D., Assistant Professor, Princess Margaret Hospital, University Health Network in Toronto, Canada, focused on results from studies by the MMRC Validation Team, in collaboration with Sunesis scientists, of SNS-032 in human myeloma cell lines and primary multiple myeloma cells. SNS-032 demonstrated broad, mechanism-based activity in the human my
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