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Successful Phase I/II Clinical Trial for BiondVax Pharmaceuticals' Universal Flu Vaccine
Date:12/7/2009

RECHOVOT, Israel, Dec. 7 /PRNewswire/ --

  • 60 people, males and females, aged 18-49, participated in the trial
  • The antibodies generated by the vaccine specifically identified several strains of influenza, including the swine flu strain
  • BiondVax's CEO Dr. Ron Babecoff: "This is an important indication along the way towards the realization of the Company's vision of ensuring protection against all flu strains with a single vaccination."

BiondVax Pharmaceuticals Ltd. (TASE: BNDK), an Israeli biopharmaceutical company at the forefront of the development of a Universal Influenza Vaccine, announced the success of the Phase I/II clinical trial of the Company's Multimeric-001 Universal Flu Vaccine, in trials conducted at the Sourasky Medical Center in Tel Aviv, Israel. The Phase I/II trial was a randomized, single-blind, placebo-controlled, escalating double-dose safety study in which a total of 60 participants, males and females aged 18-49, received two intramuscular injections containing the Multimeric-001 vaccine, either with or without adjuvant, and at two different dose levels.

The clinical trial results show that BiondVax's Multimeric-001 Universal Flu Vaccine is safe to use at all doses tested, both with and without adjuvant.

In addition, it was found that the Multimeric-001 Universal Flu Vaccine activated, in a statistically significant manner when compared with placebo, the two arms of the human immune system - the humoral (antibody) arm and the cellular arm. All participants who received the vaccine showed a high level of antibodies against the Multimeric-001 Universal Flu Vaccine. These antibodies also specifically identified a number of different strains of influenza, including the swine flu strain (A/H1N1).

In this Phase I/II clinical trial, certain cellular parameters were examined, and it was fou
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SOURCE BiondVax Pharmaceuticals Ltd.
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