Study of Lacrisert(R) Dry Eye Insert Published in The Ocul... (the 2009 Annual Meeting of the Associati...)

Study of Lacrisert(R) Dry Eye Insert Published in The Ocular Surface

Date:8/19/2009

the 2009 Annual Meeting of the Association for Research in Vision and Ophthalmology (ARVO) and the 145th Annual Meeting of the American Ophthalmological Society (AOS).

Findings of the Lacrisert Retrospective Study

Key findings of the Lacrisert retrospective case series study published in the July 2009 edition of The Ocular Surface include:

Of the 80 study patients, 73 (91%) were currently using the insert. Among those, 57 (78.1%) used the insert once a day, and 11 (15.1%) used the insert twice a day.
Length of therapy with the insert ranged from 10 days to over 26 years. The median length of therapy was 5.3 years. Fifty-two patients (65%) had used the inserts for over 2 years.
Overall, 72.6% of patients currently using the insert (N = 73) demonstrated improvement in symptoms. In eight patients (11%) symptoms were controlled. Only one patient reported no change.
Five patients (6.2%) wore contact lenses. All five patients were still using the insert as of the evaluation date, and four of these had been classified as having severe keratitis. The keratitis was improved in all five contact lens patients since the date of first diagnosis.

* Some patients may require the flexibility of twice-daily dosing for optimal results.

Study Methodology

A retrospective case series study from 9 different ophthalmic practices of 80 dry eye patients prescribed the hydroxypropyl cellulose ophthalmic insert in the previous 2 years was performed. The purpose of the study was to identify the demographics and etiology of patients treated and to determine whether patients who used the insert experienced improvement in symptoms. Data were abstracted from patient medical records using a standardized paper form by research nurses employed by each office or by a HIPAA-certified nurse. The study was approved and
'/>"/>

0

GOOD

Page: 1 2 3 4
Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
4. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
5. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
6. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
7. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
8. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
9. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
10. MacroGenics Begins Global Phase 2/3 Protege Study in Recent-onset Type 1 Diabetes Mellitus
11. Sarasotas Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes

Post Your Comments:

Study of Lacrisert(R) Dry Eye Insert Published in The Ocul...(the 2009 Annual Meeting of the Associati...),Health