Navigation Links
Study Shows Once-Yearly Reclast Better than Risedronate at Increasing Bone Mass in Patients With Osteoporosis Caused by Glucocorticoids
Date:4/11/2008

- Glucocorticoids, commonly known as steroids, widely used to treat inflammatory conditions but can increase the risk of osteoporotic fractures

with up to 50% of patients on long-term therapy at risk(1,2) - Study of more than 800 men and women shows higher bone mineral density

with Reclast than with risedronate, a current established therapy(3)

- Regulatory approval sought for treatment and prevention of

glucocorticoid-induced osteoporosis in US

EAST HANOVER, N.J., April 11 /PRNewswire/ -- New data show that a once-yearly infusion of Reclast(R) (zoledronic acid) Injection 5mg was significantly better than risedronate at increasing bone mass in patients with osteoporosis caused by glucocorticoids, commonly known as steroids(3). These medications are widely used to treat inflammatory conditions but can cause bone loss and osteoporosis(1).

Up to 50% of patients receiving long-term glucocorticoid therapy are at increased risk of fracture due to osteoporosis(2). Glucocorticoid-induced osteoporosis (GIO) is the most prevalent form of "secondary osteoporosis," which is characterized by low bone mass that results directly from specific diseases or medications(1).

Results of a clinical study in 833 men and women were presented today at the European Congress on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (ECCEO) in Istanbul, Turkey(3).

"Recognizing and treating GIO is an important need, as glucocorticoid therapy is widely used and presents an ongoing challenge for physicians," said Professor David M. Reid, Head of the Division of Applied Medicine at University of Aberdeen, UK. "The significant efficacy of this once-yearly treatment, offering year-long bone protection, will provide a valuable treatment option for healthcare professionals treating and managing osteoporosis induced by glucocorticoids."

The trial investigated both prevention (n=288) and treatment (n=545)
'/>"/>

SOURCE Novartis Pharmaceuticals Corporation
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
4. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
5. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
6. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
7. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
8. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
9. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
10. MacroGenics Begins Global Phase 2/3 Protege Study in Recent-onset Type 1 Diabetes Mellitus
11. Sarasotas Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... , Sept. 19, 2014 /PRNewswire-iReach/ -- Market ... Hydrochloride Industry, 2009-2019 is a professional and ... Oxybutynin Hydrochloride industry. The report firstly reviews ... its classification, application and manufacturing technology. The ... manufacturers of Oxybutynin Hydrochloride listing their product ...
(Date:9/19/2014)... CHICAGO, Ill. , Sept. 19, 2014  The ... ABBV ) declared a quarterly cash dividend of $0.42 ... payable Nov. 17, 2014 to stockholders of record at ... About AbbVie AbbVie is a global, research-based biopharmaceutical ... company,s mission is to use its expertise, dedicated people ...
(Date:9/19/2014)... -- Merck (NYSE: MRK ), known as MSD outside ... , is teaming with celebrity chef and cookbook author Leticia ... an educational program encouraging Hispanics with type 2 diabetes to achieve ... to help reduce the risk of serious health problems. Hispanics in ... risk for developing type 2 diabetes than non-Hispanic white adults, and ...
Breaking Medicine Technology:Oxybutynin Hydrochloride Industry 2014-2019 Chinese Forecasts & Analysis 2Oxybutynin Hydrochloride Industry 2014-2019 Chinese Forecasts & Analysis 3Oxybutynin Hydrochloride Industry 2014-2019 Chinese Forecasts & Analysis 4Oxybutynin Hydrochloride Industry 2014-2019 Chinese Forecasts & Analysis 5Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 2Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 3Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 4Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 5
(Date:9/21/2014)... of an infant prior to 37 weeks of pregnancy ... over the past two decades. According to the ... affects nearly 500,000 babies each year, or one of ... has improved survival rates for preterm infants, questions remain ... preterm infants. , Research led by Barry M. Lester, ...
(Date:9/21/2014)... Instituting a partial smoking ban at a homeless shelter ... levels, an indicator of exposure to cigarette smoke, and ... to new research. The University of Texas Health Science ... week in the journal Addictive Behaviors . , ... fallen to 18 percent among adults, but among homeless ...
(Date:9/21/2014)... AstraZeneca’s Pulmicort is an ICS ... is used prophylactically for the maintenance treatment of ... budesonide, is an anti-inflammatory corticosteroid with a high ... includes the Pulmicort Flexhaler (budesonide) for adults and ... Pulmicort Respules for children between one and eight ...
(Date:9/21/2014)... focus on the physical activity benefits of active play, ... that for children, playing has no goal it ... fun, done alone or with friends, and it represents ... to combat boredom, sadness, fear, or loneliness." "By focusing ... aside several aspects of play that are beneficial to ...
(Date:9/21/2014)... London, United-Kingdom (PRWEB) September 22, 2014 ... Fergus Sweeney and Dr. Lilliam Rosario as keynote speakers ... Transparency”. Following keynotes from Dr. Ben Goldacre in ... Professor Lord Winston in 2011 , PhUSE again ... professions who are passionate about advancement of clinical information. ...
Breaking Medicine News(10 mins):Health News:Research evaluates neurodevelomental and medical outcomes in single family room NICU 2Health News:Research evaluates neurodevelomental and medical outcomes in single family room NICU 3Health News:UTHealth researchers study impact of smoking ban in homeless shelter 2Health News:Pulmicort Asthma Market (Epidemiology, Etiology, Symptoms, Diagnosis, Pathology) Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 2Health News:Pulmicort Asthma Market (Epidemiology, Etiology, Symptoms, Diagnosis, Pathology) Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 3Health News:Pulmicort Asthma Market (Epidemiology, Etiology, Symptoms, Diagnosis, Pathology) Forecasts to 2023 in New Report Available at LifeScienceIndustryResearch.com 4Health News:Narrow focus on physical activity could be ruining kids' playtime 2Health News:PhUSE announces Final List of Industry Influencers as Keynote Speakers 2Health News:PhUSE announces Final List of Industry Influencers as Keynote Speakers 3
... the health of your family tree? While the relatives ... holiday, taking a good look at,the family health history ... Surgeon General Steven K. Galson, M.D., M.P.H., has,declared Thanksgiving ... everyone to use the occasion to discuss and identify ...
... Fla., Nov. 20 The State of ... Services has selected,U.S. Care Management (formally Specialty ... management services to assist in improving,birth outcomes ... births and high-risk infants among Medicaid participants ...
... (BMI) is associated with higher plasma volume, which may ... obese men, according to a study in the November ... suggested that prostate cancer screening may be adversely affected ... cancer can be compromised by any factor that decreases ...
... sick children, study finds , , TUESDAY, Nov. 20 (HealthDay ... at a children,s hospital can cut rates of patient ... care unit, a new study suggests. , "This is ... so that adds to the potential that having rapid ...
... how to keep hands clean, MORRIS PLAINS, N.J., Nov. ... his/her nose or mouth. Considering that,some viruses and bacteria can ... and desks that children touch throughout the,day, it is easy ... According to the Centers for Disease Control and Prevention ...
... for fourth year to support St. Jude in ... Ohio, Nov. 20 Kay Jewelers is joining St. Jude,Children,s ... Giving,campaign. This is the fourth year for the national campaign ... in fundraising campaigns. Thanks and Giving was created by ...
Cached Medicine News:Health News:Acting Surgeon General Encourages Americans to Know Their Health History During Fourth Annual Family History Day 2Health News:Acting Surgeon General Encourages Americans to Know Their Health History During Fourth Annual Family History Day 3Health News:State of Arkansas Department of Human Services, Division of Medical Services Selects U.S. Care Management for High-Risk Obstetrics Health Management Program 2Health News:State of Arkansas Department of Human Services, Division of Medical Services Selects U.S. Care Management for High-Risk Obstetrics Health Management Program 3Health News:State of Arkansas Department of Human Services, Division of Medical Services Selects U.S. Care Management for High-Risk Obstetrics Health Management Program 4Health News:Obesity associated with lower PSA levels in men with prostate cancer 2Health News:Rapid Response Teams Can Save Hospitalized Kids 2Health News:Rapid Response Teams Can Save Hospitalized Kids 3Health News:Proper Hand Hygiene Is Key to Avoiding Illness During Cold and Flu Season 2Health News:Kay Jewelers Joins St. Jude Children's Research Hospital(R) to Kick Off Fourth Annual Thanks and Giving(R) Campaign 2Health News:Kay Jewelers Joins St. Jude Children's Research Hospital(R) to Kick Off Fourth Annual Thanks and Giving(R) Campaign 3
ELISA kit for detection of the cardiac marker Myoglobin. Kit features interchangeable reagents, E-Z Process performed at room temp, and results in less than 1 hour!...
... intended for the quantitative determination of prolactin ... in the diagnosis and treatment of disorders ... BioCheck Prolactin Quantitative Test is based on ... immunosorbent assay. The assay system utilized sheep ...
... assay is an immunometric ('sandwich') ... of Prolactin in human serum ... sample is bound by 2 ... epitopes. One antibody is attached ...
... ELISA Kit is enzyme immunoassay kit ... Prolactin (PRL) concentration in serum. Enzyme ... determination of many protein hormones in ... sensitive, reproducible, rapid and specific assay. ...
Medicine Products: