Navigation Links
Study Shows Efficacy of C1-Esterase Inhibitor Concentrate in Treating Acute Attacks of Hereditary Angioedema in Children and Adolescents
Date:11/5/2011

BOSTON, Nov. 5, 2011 /PRNewswire/ -- New findings demonstrate that treatment with C1-esterase inhibitor (C1-INH) concentrate is effective in treating acute swelling attacks in children and adolescents with type I or type II hereditary angioedema (HAE), a rare and serious genetic disorder. Study results show that the outcomes of treatment with C1-INH during acute HAE attacks in children and adolescents are comparable to the outcomes observed in adults.  Results of the analysis will be presented today at the 2011 American College of Allergy, Asthma & Immunology (ACAAI) Annual Meeting.

"Hereditary angioedema is a debilitating and potentially life-threatening disease that can be passed from parent to child and impact entire families," said Lynda Schneider, M.D., Associate Professor of Pediatrics at Children's Hospital Boston and lead investigator. "While the benefits of C1-esterase inhibitor have been clearly demonstrated in treating adults with acute attacks of HAE, limited research exists regarding the use of the therapy in pediatric patients. Our findings show that treatment with C1-INH concentrate is consistent across age groups, with the average time to onset of symptom relief and the average time for complete resolution of symptoms comparable in children, adolescents and adults."

HAE is a genetic disorder caused by a deficiency of C1-INH and is inherited in an autosomal dominant manner. Symptoms of HAE include episodes of edema or swelling in the face, abdomen, larynx and extremities. Patients who have abdominal attacks of HAE can experience episodes of severe pain, diarrhea, nausea and vomiting caused by swelling of the intestinal wall. HAE attacks that involve the face can cause painful distortion and painful swelling.  Diagnosis of HAE requires a blood test to confirm low or abnormal levels of C1-INH.

Study Design and Key Findings

In this retrospective, consecutive, cohort analysis of pediatric and adolescent
'/>"/>

SOURCE CSL Behring
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
4. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
5. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
6. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
7. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
8. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
9. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
10. MacroGenics Begins Global Phase 2/3 Protege Study in Recent-onset Type 1 Diabetes Mellitus
11. Sarasotas Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... SALT LAKE CITY , Aug. 28, 2014 /PRNewswire-iReach/ ... in 2000 by service academy graduates, has published a ... its concentrated, three-day Leadership Excellence Course . In ... the  Leadership Excellence Course to Albuquerque , ... Tucson . Photo - http://photos.prnewswire.com/prnh/20140828/140814 ...
(Date:8/28/2014)... , August 28, 2014 ... "DNA diagnostics Market (products, applications, techniques, end users ... Growth and Forecast, 2013 - 2020," indicates that ... billion by 2020 registering a CAGR of 9.8% ... accurate diagnosis and cost effectiveness over alternative diagnostic ...
(Date:8/28/2014)... , Aug. 28, 2014   Venaxis, Inc. ... focused on obtaining FDA clearance for and commercializing its ... test for aiding in identifying children, adolescent, and young ... low risk for appendicitis, today announced it will present ... 16 th Annual Global Investment Conference being held ...
Breaking Medicine Technology:Academy Leaders Publishes Case Study on Work with Global Pharmaceutical Company 2Academy Leaders Publishes Case Study on Work with Global Pharmaceutical Company 3Academy Leaders Publishes Case Study on Work with Global Pharmaceutical Company 4Academy Leaders Publishes Case Study on Work with Global Pharmaceutical Company 5DNA Diagnostics Market is Expected to Reach $19 Billion by 2020 - Allied Market Research 2DNA Diagnostics Market is Expected to Reach $19 Billion by 2020 - Allied Market Research 3Venaxis to Present at September Investor Conferences 2Venaxis to Present at September Investor Conferences 3
... Model of Diabetes with Haptoglobin 2-2 Genotype Show, ... Transport, MONTVALE, N.J., March 31 Synvista,Therapeutics, ... a study of diabetic mice,with the Haptoglobin 2-2 ... Haptoglobin (Hp)-Hemoglobin (Hb) complex may result in a ...
... is now enrolling ... patients, ... announced today the start of a Phase III clinical trial,studying LY450139, an ... LY450139 is being tested,to see if it can slow the progression associated ...
Cached Medicine Technology:Synvista Therapeutics Presents New Preclinical Data Demonstrating the Value of Haptoglobin Genotype Testing In Diabetes at ACC Scientific Sessions 2Synvista Therapeutics Presents New Preclinical Data Demonstrating the Value of Haptoglobin Genotype Testing In Diabetes at ACC Scientific Sessions 3Synvista Therapeutics Presents New Preclinical Data Demonstrating the Value of Haptoglobin Genotype Testing In Diabetes at ACC Scientific Sessions 4Lilly Launches Its First Phase III Trial for Treatment of Alzheimer's Disease 2Lilly Launches Its First Phase III Trial for Treatment of Alzheimer's Disease 3Lilly Launches Its First Phase III Trial for Treatment of Alzheimer's Disease 4Lilly Launches Its First Phase III Trial for Treatment of Alzheimer's Disease 5Lilly Launches Its First Phase III Trial for Treatment of Alzheimer's Disease 6
(Date:8/28/2014)... (PRWEB) August 28, 2014 ABC television ... the 49th MDA Show of Strength Telethon airing Sunday, ... country to help raise funds and awareness to help ... affected by muscle disease. , Viewers tuning into the ... enjoy heart-felt appeals and introductions from some of the ...
(Date:8/28/2014)... Allegheny Health Network and ... designed to advance sports nutrition education, concussion awareness ... scholastic athletes and their families across western Pennsylvania. ... Initiative will offer a comprehensive and multi-disciplined educational ... dynamics involved in pursuing athletic excellence,” said Come ...
(Date:8/28/2014)... (PRWEB) August 28, 2014 Gurnick Academy ... MRI Technology program is re-accredited for the 5 years ... Resonance Imaging Technologists (ARMRIT). , “We are very ... constantly improving our program to make sure we provide ... lot of interest in MRI field nowadays and I ...
(Date:8/28/2014)... problem in winemaking is "stuck fermentation," when yeast that ... carbon dioxide prematurely shuts down, leaving the remaining sugar ... the wine. , A team of researchers including UC ... communication system behind this problem. Working through a ... itself -- the system enables bacteria in fermenting wine ...
(Date:8/28/2014)... Tenn. The New England Journal of Medicine ... clinical trial of a drug shown to safely reduce ... volunteers intranasally infected with respiratory syncytial virus (RSV). ... of Tennessee Health Science Center researcher Infectious Disease Specialist ... , RSV is the most common cause ...
Breaking Medicine News(10 mins):Health News:ABC Stars Unite to Fight Back Against Muscle Disease During MDA Show of Strength Telethon 2Health News:ABC Stars Unite to Fight Back Against Muscle Disease During MDA Show of Strength Telethon 3Health News:ABC Stars Unite to Fight Back Against Muscle Disease During MDA Show of Strength Telethon 4Health News:Allegheny Health Network and Come Ready Nutrition Announce Regional Partnership 2Health News:Allegheny Health Network and Come Ready Nutrition Announce Regional Partnership 3Health News:Allegheny Health Network and Come Ready Nutrition Announce Regional Partnership 4Health News:Gurnick Academy’s MRI Program Is Re-Accredited by ARMRIT for the 5 Years 2Health News:Prions can trigger 'stuck' wine fermentations, researchers find 2Health News:DeVincenzo study breakthrough in RSV research 2
... in losing weights and are not healthy attempts to do ... Dieticians consulted by WebMD also agree and say that spending ... ,The growing rate of obesity in the United States ... the increasing childhood obesity. Cynthia Sass, MPH, MA, RD, LDN, ...
... families in North Carolina and Virginia found evidence of ... to call for pesticide safety training for workers’ spouses. ... from Wake Forest University School of Medicine report that ... pesticide exposure than had been found in similar studies ...
... those pills to beat the blues, just think positive instead. ... the key// to contentment lies in the mind and people ... from depression. ,D.V. Pasupuleti, director of neurology ... Michigan State University, believes anyone can create their own happiness ...
... pay compensation and apologise to a young woman orphaned by ... ,Beijing Chaoyang District Court ordered the local China Times ... and issue an apology on its front page for a ... of the woman and the story of her sufferings after ...
... According to the parliament's Health Select Committee the charges levied ... reviewed//. ,It pointed out to the fact that ... have any comprehensible underlying principles. Hence it concluded in its ... changed. These charges have a woeful effect on the patients ...
... region, Meghalaya Health mininster E D Marak was today hospitalised ... who returned from the Garo hills on Saturday, was admitted ... son told PTI., ,The Health minister had accompanied chief ... Garo Hills district town Tura., ,Malaria had claimed 40 ...
Cached Medicine News:Health News:Research Documents Children’s Exposure to Pesticide 2Health News:Inculcating Positive Thoughts Could Eliminate Depressive Mood 2
... many benefits of fibre bronchoscopy: The HF-compatible ... which all other fibre bronchoscopes are measured., ... from PENTAX, including the FB-19TV, FB-18V and ... FB-10V and the pediatric FB-8V, offer much ...
... High performance fiberoptic imaging from the ... has improved its fiberscope range, focussing ... and enhanced image performance. Olympus has ... for diagnosis and therapy in the ...
Fujinon's standard fiberoptic bronchoscope is fully submersible and offers a large image for more comfortable and efficient observation....
... fiberoptic imaging from the latest 60 ... its fiberscope range, focussing on providing ... image performance. Olympus has a impressive ... and therapy in the respiratory tract ...
Medicine Products: