Navigation Links
Study Shows Benefits of a High Omega-3 Diet in Older Adults
Date:8/13/2008

High Omega-3 Fat Intake Improves Insulin Sensitivity and Reduces Inflammatory Markers, But Does Not Alter Endocrine Responsiveness

PHOENIX, Aug. 13 /PRNewswire-USNewswire/ -- A study conducted by Phoenix-based Kronos Longevity Research Institute (KLRI) found that a diet high in omega-3 fat improves insulin sensitivity and reduces inflammatory markers, but does not alter endocrine responsiveness. This study was recently published in Hormones and Metabolic Research.

"As we age, hormone secretion and cell responsiveness decrease, possibly due to loss of cell membrane fluidity or alteration of the membrane," said Dr. S. Mitchell Harman, MD, PhD, Director and President of Kronos Longevity Research Institute. "Animal studies have shown that omega-3 fatty acids may help hormone signals get into cells whose cell membrane has been stiffened by age."

Omega-3 fatty acids are polyunsaturated fatty acids found in certain natural foods, such as fish, especially salmon and tuna. They are known to help protect against heart disease. KLRI examined the effects of a diet high in omega-3 fatty acids on the loss of normal hormone balance that occurs during normal aging. KLRI recruited men and women over the age of 60 to investigate whether a high omega-3 fatty acid diet would improve their endocrine function.

"It is possible to achieve significant changes in the fat molecules in cell membranes after relatively short periods of changes in one's diet," said Panayiotis D. Tsitouras, MD, Clinical Director at KLRI. "We wanted to see if we could improve mental function, hormone levels at rest and/or under stress, and immune function, toward a pattern more like that of younger individuals."

In this study, all participants were given a conventional Western diet with defined fat and daily intake of olive/corn oil mix for six weeks. For the next eight weeks, participants were placed on a high omega-3 content fish diet with additional supplementation of fish oil, high in omega-3 polyunsaturated fat. This study had administered the highest known level of omega-3 than previous studies.

During the last week, membrane fatty acids were measured on each diet. Insulin sensitivity was also assessed. The results showed that in a diet with a high intake of omega-3, triglycerides were reduced in women and free fatty acids were reduced in men. Serum C-reactive protein was also reduced with a high omega-3 diet. No changes were found in metabolic parameters or hormone responses.

"We concluded that a diet high in omega-3 increases insulin sensitivity and reduces inflammatory markers," said Harman. "However, it did not alter endocrine responsiveness after eight weeks."

These findings are consistent with other studies that have found that diets high in omega-3 and/or omega-3 supplements have anti-inflammatory benefits. Omega-3 fats are abundant in Japanese and Mediterranean diets, and are believed to contribute to low heart disease rates in those regions.

"Clearly, a diet rich in omega-3 fats is beneficial to one's heart health," said Tsitouras. "This study along with similar studies in the future will shed new light and pave the way for preventative measures for heart disease."

About Kronos Longevity Research Institute

Kronos Longevity Research Institute (KLRI) is a not-for-profit, 501(c)(3) organization that conducts state-of-the-art clinical translational research on the prevention of age-related diseases and the extension of healthier human life. KLRI tests new strategies to detect and prevent chronic diseases associated with aging and investigates the effects of innovative interventions to slow the aging process and improve health outcomes for older persons. In addition, KLRI helps the medical and lay communities understand important aging issues. KLRI research findings support a healthier quality of life and a robust lifestyle in our senior years. For more information, visit http://www.kronosinstitute.org.


'/>"/>
SOURCE Kronos Longevity Research Institute
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. NewCardio Announces Positive Results From Third Clinical Validation Study
2. M. D. Anderson to Initiate Clinical Validation Study on Rosetta Genomics MicroRNA-based Diagnostic Assay Identifying the Origin of Cancer Metastases
3. Emisphere Announces Recruitment of Novartis Phase III Study for Oral Osteoporosis Treatment
4. Pharmasset Reports Preliminary Results of a 4-week Combination Study of R7128 for the Treatment of Chronic Hepatitis C
5. Icon Bioscience Completes Enrollment in Phase I Study of Novel Ophthalmic Drug Candidate
6. FDA Reviewing Biomoda Submission for Cancer Screening Study
7. Top-Line Results of Boceprevir Phase II Study Showed High Rate of Sustained Response (SVR) in Genotype 1 Treatment-Naive Hepatitis C Patients
8. New AVAC Report on Pre-Exposure Prophylaxis Calls for Immediate Planning to Anticipate Study Results of Potential New HIV Prevention Option
9. Genmab and GlaxoSmithKline Announce Positive Top-Line Results in Ofatumumab Chronic Lymphocytic Leukemia Pivotal Study
10. Study Reveals Novel LCD Solution Provides Significant Benefits Versus Calcipotriol In Treatment Of Moderate Psoriasis
11. First Ever Study on Alzheimers Disease Treatment in Hispanics Presented at Major Medical Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... June 24, 2016  Collagen Matrix, Inc., ("Collagen ... and manufacturing of collagen and mineral based medical ... that Bill Messer has joined the ... further leverage the growing portfolio of oral surgery, ... Bill joins the Collagen Matrix executive team ...
(Date:6/24/2016)... 2016 Research and Markets ... Electronics 2015-2025: Applications, Technologies, Forecasts" report to ... In-Mold Electronics, Smart Skin, Structural Health Monitoring, Composite ... Structural electronics involves electronic and/or electrical components and ... dumb structures such as vehicle bodies or conformally ...
(Date:6/24/2016)... DUBLIN , June 24, 2016 ... "The World Market for Companion Diagnostic Tests" report to ... World Market for Companion Diagnostics The World ... diagnostic and personalized medicine diagnostics. Market analysis in the report ... Diagnostics Test Market (In Vitro Diagnostic Kits) by Region (N. ...
Breaking Medicine Technology:
(Date:6/25/2016)... D.C. (PRWEB) , ... June 25, 2016 , ... ... discuss health policy issues and applications at AcademyHealth’s Annual Research Meeting June 26-28, ... their work on several important health care topics including advance care planning, healthcare ...
(Date:6/25/2016)... Beach, CA (PRWEB) , ... June 25, 2016 , ... ... UCLA with Magna Cum Laude and his M.D from the David Geffen School of ... Diego and returned to Los Angeles to complete his fellowship in hematology/oncology at the ...
(Date:6/24/2016)... ... 24, 2016 , ... Those who have experienced traumatic events may suffer from ... avenues, such as drug or alcohol abuse, as a coping mechanism. To avoid this ... coping following a traumatic event. , Trauma sufferers tend to feel a range of ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... for accelerated orthodontic treatment. Dr. Cheng has extensive experience with all areas of ... AcceleDent, and accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Haute Beauty ... Barry M. Weintraub as a prominent plastic surgeon and the network’s newest partner. ... and the most handsome men, look naturally attractive. Plastic surgery should be invisible.” ...
Breaking Medicine News(10 mins):