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Study Reveals Novel LCD Solution Provides Significant Benefits Versus Calcipotriol In Treatment Of Moderate Psoriasis
Date:7/31/2008

Clinical Data Presented at American Academy of Dermatology Summer Meeting

PRINCETON, N.J., July 31 /PRNewswire/ -- NeoStrata today announced findings from an ongoing 12-week study that demonstrates benefits of a novel topically applied LCD (coal tar) solution (Psorent(TM)) versus calcipotriol cream (Dovonex(R)) in treatment of moderate plaque psoriasis. Specifically, results of an interim analysis reveal the LCD solution is outperforming calcipotriol cream in achieving improvement of psoriasis symptoms (PASI 75) and is significantly better in reducing redness/irritation at both the 2- and 12-week point. Further, patient satisfaction with the aesthetics and ease of use of the LCD solution is high, with nearly 90% of patients expressing an interest in continuing to use the medication after the study's completion.

The clinical data, from a trial conducted by investigator Alexa Kimball, MD, MPH, Massachusetts General and Brigham and Women's Hospitals, Boston, are on display in a Scientific Poster at the Summer Academy Meeting of the American Academy of Dermatology (AAD), July 31 - August 3 in Chicago, IL.

"While coal tar is widely viewed as a very effective treatment for psoriasis, its historically unappealing aesthetic profile has created problems with patient compliance and reduced overall treatment satisfaction," said Dr. Kimball. "These findings demonstrate the non-prescription LCD treatment is at least as effective as a leading prescription medication. Further, they suggest the aesthetically pleasing formulation of the LCD treatment offers a much-needed alternative for safe, effective, easy-to-use topical drug therapy for mild to moderate psoriasis - a welcome tool in our armamentarium."

The 12-week study is evaluating the safety and efficacy of the new topically applied 15% LCD against calcipotriol cream in treatment of 60 patients with moderate plaque psoriasis. The findings, representing interim results for 48 patients, evaluate c
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