Navigation Links
Study Results of GAMMAGARD S/D and GAMMAGARD LIQUID in Patients with Mild-to-Moderate Alzheimer's Disease Announced
Date:4/17/2008

erian/Weill Cornell group on the analysis of brain imaging data from the study and also presented findings at the AAN meeting. She reported that GAMMAGARD-treated participants had observable changes in brain metabolism. While energy metabolism in the brain was an exploratory endpoint in the study it was preserved or improved in 10 out of 13 patients after six months of GAMMAGARD S/D and GAMMAGARD LIQUID treatment.

"Brain metabolism usually decreases progressively in patients with Alzheimer's disease," said Dr Mosconi. "The changes on PET scans of these Alzheimer's patients after six months of GAMMAGARD S/D and GAMMAGARD LIQUID are encouraging."

The Phase II study also evaluated brain metabolism in patients treated with GAMMAGARD S/D and GAMMAGARD LIQUID compared to those who received placebo based on 18F-fluoro-deoxyglucose Positron Emission Tomography (PET) (FDG-PET) scans, which are sometimes used in the diagnosis of Alzheimer's disease. Across brain regions usually affected by Alzheimer's disease, in this study the GAMMAGARD S/D and GAMMAGARD LIQUID groups were observed to show 16 percent higher brain metabolism after treatment compared to placebo (12-18 percent increase in the hippocampi, 14-17 percent increase in parieto-temporal cortices and 21-24 percent increase in the thalami).

Phase III Study

The Phase III study is sponsored by the National Institutes of Health (NIH) and Baxter. The study protocol was submitted to the U.S. Food and Drug Administration for review, with the intention of initiating patient recruitment later in 2008. The trial will include approximately 35 leading academic centers in the United States that are members of the Alzheimer's Disease Cooperative Study (ADCS). The involvement of the ADCS and NIH in the conduct of the Phase III trial will ensure the highest level of independent scientific evaluation of the potential role of GAMMAGARD S/D and GAMMAGARD LIQUID in the treatment of Alzheimer's.

About Alz
'/>"/>

SOURCE Baxter International Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
4. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
5. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
6. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
7. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
8. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
9. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
10. MacroGenics Begins Global Phase 2/3 Protege Study in Recent-onset Type 1 Diabetes Mellitus
11. Sarasotas Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... DUBLIN , Jan. 15, 2014  Research and Markets ... "Dental Consumables Market - Global Industry Analysis, Size, ... report to their offering. (Logo: ... products which are used on patients in order to ...
(Date:1/15/2014)... Foundation today announced it has established a relief fund ... weather that has gripped much of the nation. AARP and ... to support these emergency relief efforts AARP and AARP Foundation ... up to $500,000 in aid. The matching program will be ...
(Date:1/15/2014)... Jan. 15, 2014  Celsion Corporation (the "Company") (NASDAQ: ... from institutional investors to purchase an aggregate of approximately ... at-the-market registered direct offering, led by a dedicated health ... purchase agreements with these investors pursuant to which the ...
Breaking Medicine Technology:Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 2Celsion Corporation Announces $15 Million At-The-Market Registered Direct Offering 3
... 2011 Ortho-McNeil-Janssen Pharmaceuticals, Inc. is initiating a ... 3mg Tablets, marketed by Janssen Division of Ortho-McNeil-Janssen ... Tablets, marketed by Patriot Pharmaceuticals, LLC, a wholly ... stem from two consumer reports of an uncharacteristic ...
... -- Tianyin Pharmaceutical Co., Inc. (NYSE Amex: TPI, ... patented biopharmaceutical medicine, modernized traditional Chinese medicine, branded ... the non-cash, non-operational financial impact from the warrants ... (formerly EITF 07-05). In the ...
Cached Medicine Technology:Ortho-McNeil-Janssen Pharmaceuticals, Inc. Voluntarily Recalls One Lot of RISPERDAL® Tablets and One Lot of Risperidone Tablets 2Ortho-McNeil-Janssen Pharmaceuticals, Inc. Voluntarily Recalls One Lot of RISPERDAL® Tablets and One Lot of Risperidone Tablets 3Ortho-McNeil-Janssen Pharmaceuticals, Inc. Voluntarily Recalls One Lot of RISPERDAL® Tablets and One Lot of Risperidone Tablets 4Ortho-McNeil-Janssen Pharmaceuticals, Inc. Voluntarily Recalls One Lot of RISPERDAL® Tablets and One Lot of Risperidone Tablets 5Ortho-McNeil-Janssen Pharmaceuticals, Inc. Voluntarily Recalls One Lot of RISPERDAL® Tablets and One Lot of Risperidone Tablets 6Ortho-McNeil-Janssen Pharmaceuticals, Inc. Voluntarily Recalls One Lot of RISPERDAL® Tablets and One Lot of Risperidone Tablets 7TPI Discusses Non-Cash Non-Operational Financial Impact from Warrants 2TPI Discusses Non-Cash Non-Operational Financial Impact from Warrants 3
(Date:7/11/2014)... 2014 As part of its ... LLP has been closely monitoring the ongoing meeting ... Obstetrics and Gynecology Devices Panel, which has ... cancer risks associated with the use of power ... a report published by Dow Jones Business News, ...
(Date:7/11/2014)... 2014 Operators and owners ... in fuel costs now that model 2019 ... GHG standards are phasing in 2014-2018 ... themselves to install new features into their ... technologies , 2.    Efficient driveline components which reduce ...
(Date:7/11/2014)... July 11, 2014 The report ... Specialty Nutrients, Animal Feed), Applications (Regular, Therapeutic, Preventive ... Global Trends & Forecasts to 2019 ” defines ... analysis and forecasting of the market value of ... the driving and restraining factors for the global ...
(Date:7/11/2014)... Presently, disposable medical suppliers call for ... supplies segment. During the past two decades, the world ... an average 12.5% per year), primarily owing to the ... US is the largest market for disposable medical supplies ... The second position is held by Europe with a ...
(Date:7/11/2014)... The Corn Farming industry experienced ... the heels of fresh biofuel demand. The Federal Renewable ... larger share of their farmland to cultivating high-value corn ... the mixing of 5.0% renewable content in gasoline across ... States created a key export market for Canadian corn, ...
Breaking Medicine News(10 mins):Health News:Morcellator Lawsuit News: Bernstein Liebhard LLP Notes Financial Ties Between FDA Advisory Panel Members and Manufacturers of Power Morcellators 2Health News:Morcellator Lawsuit News: Bernstein Liebhard LLP Notes Financial Ties Between FDA Advisory Panel Members and Manufacturers of Power Morcellators 3Health News:Morcellator Lawsuit News: Bernstein Liebhard LLP Notes Financial Ties Between FDA Advisory Panel Members and Manufacturers of Power Morcellators 4Health News:LeaseQ Agrees the Latest Round of Greenhouse Gas Rules Could Increase the Cost of Truck Acquisition and Maintenance 2Health News:LeaseQ Agrees the Latest Round of Greenhouse Gas Rules Could Increase the Cost of Truck Acquisition and Maintenance 3Health News:Probiotic Ingredient Market worth $1,732.8 Million by 2019 - A Report by MarketsandMarkets 2Health News:Probiotic Ingredient Market worth $1,732.8 Million by 2019 - A Report by MarketsandMarkets 3Health News:Probiotic Ingredient Market worth $1,732.8 Million by 2019 - A Report by MarketsandMarkets 4Health News:Probiotic Ingredient Market worth $1,732.8 Million by 2019 - A Report by MarketsandMarkets 5Health News:Global Disposable Medical Supplies Market to See Robust Growth Through Next Decade, According to New TriMark Report Available at MarketPublishers.com 2Health News:Global Disposable Medical Supplies Market to See Robust Growth Through Next Decade, According to New TriMark Report Available at MarketPublishers.com 3Health News:Corn Farming in Canada Industry Market Research Report Now Available From IBISWorld 2Health News:Corn Farming in Canada Industry Market Research Report Now Available From IBISWorld 3
... Care Habits , CHICAGO, Feb. 11 Valentine,s Day is ... in others? The smile. A national survey from ... the smile outranked eyes, hair and the body as the ... comes to taking care of their teeth and gums. The ...
... General Kenneth P. Moritsugu urged members of the American ... and patient-care skills to prevent diseases such as obesity ... in the United States and to educate Americans to ... was Deputy Surgeon General from 1998 to 2006 and ...
... JACKSONVILLE, Fla., Feb. 11 Blue Cross and Blue ... has awarded the Florida Literacy Coalition (FLC) a three-year ... initiative. The goal of the grant is to create ... provide health-education resources for local adult ESOL (English for ...
... Market Currently Represents More Than 15% of Total ... Growth Systems, Inc. (OTC Bulletin Board: CGSY)), the ... today announced that its 2009 sales strategy will ... Global Capacity,s healthcare vertical market, which represents more ...
... The Quantum Group, Inc. ( NYSE Alternext US: ... Martinez, Senior Vice President and Chief Technology & Innovations ... St. Thomas University Healthcare Seminar later today entitled ... Martinez will contribute to the event as a ...
... from recycled plastic bottles, the new Airnamic Green from Alen Corp. ... pet dander, grass and tree pollen, mold spores and other allergens ... bottles provides consumers with an anti-microbial, moisture resistant, convenient and cost-effective ... ...
Cached Medicine News:Health News:Survey Finds Smile is 'Most Attractive' Physical Feature 2Health News:Registered Dietitians Can Do Much to Help Educate Americans and Eliminate Health Disparities in U.S., Says Former Surgeon General 2Health News:Registered Dietitians Can Do Much to Help Educate Americans and Eliminate Health Disparities in U.S., Says Former Surgeon General 3Health News:BCBSF and FLC Establish Florida Health Literacy Grants Program 2Health News:Global Capacity Reports Momentum in Healthcare Market 2Health News:Global Capacity Reports Momentum in Healthcare Market 3Health News:Quantum Executive Pete Martinez Invited to Participate in University Health Seminar 2Health News:Quantum Executive Pete Martinez Invited to Participate in University Health Seminar 3Health News:Quantum Executive Pete Martinez Invited to Participate in University Health Seminar 4Health News:Can a New Green Product Made From Recycled Plastic Soda Bottles Provide Cleaner Indoor Air and a Healthier Home? 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: