Navigation Links
Study Results of GAMMAGARD S/D and GAMMAGARD LIQUID in Patients with Mild-to-Moderate Alzheimer's Disease Announced
Date:4/17/2008

erian/Weill Cornell group on the analysis of brain imaging data from the study and also presented findings at the AAN meeting. She reported that GAMMAGARD-treated participants had observable changes in brain metabolism. While energy metabolism in the brain was an exploratory endpoint in the study it was preserved or improved in 10 out of 13 patients after six months of GAMMAGARD S/D and GAMMAGARD LIQUID treatment.

"Brain metabolism usually decreases progressively in patients with Alzheimer's disease," said Dr Mosconi. "The changes on PET scans of these Alzheimer's patients after six months of GAMMAGARD S/D and GAMMAGARD LIQUID are encouraging."

The Phase II study also evaluated brain metabolism in patients treated with GAMMAGARD S/D and GAMMAGARD LIQUID compared to those who received placebo based on 18F-fluoro-deoxyglucose Positron Emission Tomography (PET) (FDG-PET) scans, which are sometimes used in the diagnosis of Alzheimer's disease. Across brain regions usually affected by Alzheimer's disease, in this study the GAMMAGARD S/D and GAMMAGARD LIQUID groups were observed to show 16 percent higher brain metabolism after treatment compared to placebo (12-18 percent increase in the hippocampi, 14-17 percent increase in parieto-temporal cortices and 21-24 percent increase in the thalami).

Phase III Study

The Phase III study is sponsored by the National Institutes of Health (NIH) and Baxter. The study protocol was submitted to the U.S. Food and Drug Administration for review, with the intention of initiating patient recruitment later in 2008. The trial will include approximately 35 leading academic centers in the United States that are members of the Alzheimer's Disease Cooperative Study (ADCS). The involvement of the ADCS and NIH in the conduct of the Phase III trial will ensure the highest level of independent scientific evaluation of the potential role of GAMMAGARD S/D and GAMMAGARD LIQUID in the treatment of Alzheimer's.

About Alz
'/>"/>

SOURCE Baxter International Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
4. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
5. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
6. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
7. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
8. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
9. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
10. MacroGenics Begins Global Phase 2/3 Protege Study in Recent-onset Type 1 Diabetes Mellitus
11. Sarasotas Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... , Sept. 16, 2014   Vestagen Technical Textiles, ... patient experience at hospitals. The myComfort™ line of patient ... barrier fabric that is fluid repellant, breathable and in ... the growth of bacteria on the fabric i . ... plays in the chain of transmission. We want myComfort ...
(Date:9/16/2014)... Sept. 16, 2014  Synereca Pharmaceutics, Inc. ... orally active drugs that restore or increase ... a $1.4 million convertible debt financing. Accele ... sciences accelerator Accele Biopharma, Inc., led the ... nationally recognized private not-for-profit corporation focused on ...
(Date:9/16/2014)... N.Y. , Sept. 16, 2014 ... the world,s largest provider of health care products ... medical practitioners, announced today that Stanley M. Bergman, Henry ... will participate in a healthcare services panel at ...  Joining Mr. Bergman will be Dr. Stohler, Dean ...
Breaking Medicine Technology:New Vestagen Patient Garments Aim to Minimize Pathogen Transmission Inside Hospitals 2Synereca Pharmaceuticals Announces Financing Led by Accele Venture Partners 2Synereca Pharmaceuticals Announces Financing Led by Accele Venture Partners 3Synereca Pharmaceuticals Announces Financing Led by Accele Venture Partners 4Henry Schein To Present At The Leerink Partners Services Roundtable 2
... pharmaceutical products - particularly those that are first-in-class, socially ... not only external disease state communication but also internal ... a product for a new or relatively unknown condition ... the new disease before introducing a new product to ...
... Company (NYSE: LLY ) today announced that the ... a prior ruling by the U.S. District Court for the ... the company,s method-of-use patent on Strattera® (atomoxetine). In the case ... et al, the court ruled in favor of Lilly, ...
Cached Medicine Technology:Building Support for a New Product Through Effective Internal Disease State Communication 2U.S. Court of Appeals Affirms Validity of Lilly's Strattera Patent 2
(Date:9/16/2014)... Dotinga HealthDay Reporter , MONDAY, ... baldness may face a higher risk of developing an aggressive ... new study suggests. But, the study authors noted that ... of baldness should be concerned. Their study only found an ... did not prove cause and effect. "It is conceivable ...
(Date:9/16/2014)... After working together for eight years and ... fertility centers in the late 1990s and early 2000s, Dr. ... hometown of New York City to launch Chelsea Fertility of ... , Chelsea Fertility NYC offers full service fertility treatment ... New York Tri-State Area, and provides equal access to care ...
(Date:9/16/2014)... New Jersey (PRWEB) September 16, 2014 ... Infinity Development Partners of San Antonio, TX. has been ... Army facilities located throughout the US, including Alaska and ... Army’s Energy Initiatives Task Force (EITF) and the Corps ... a $7 Billion MATOC primarily to fund renewable and ...
(Date:9/16/2014)... Alachua, FL (PRWEB) September 16, 2014 ... technology company focused on the peripheral nerve repair market, ... the American Society for Surgery of the Hand (ASSH) ... John B. Hynes Convention Center in Boston, MA. , ... outcomes in surgical nerve repair, featuring a discussion by ...
(Date:9/16/2014)... September 16, 2014 Much of the ... major extended drought crisis that in many regions affects ... the many individuals who are dedicated to solving the ... solutions overlook large portion of the problem. Partial solutions, ... crises.     , Grigg explained his, “total water management” concept ...
Breaking Medicine News(10 mins):Health News:Male Pattern Baldness Tied to Prostate Cancer, Study Suggests 2Health News:Male Pattern Baldness Tied to Prostate Cancer, Study Suggests 3Health News:Chelsea Fertility NYC Offers New and Affordable Fertility Treatment Options for Patients in the New York Tri-State Area 2Health News:Chelsea Fertility NYC Offers New and Affordable Fertility Treatment Options for Patients in the New York Tri-State Area 3Health News:Chelsea Fertility NYC Offers New and Affordable Fertility Treatment Options for Patients in the New York Tri-State Area 4Health News:Solar Construction Opportunity at U.S Army Installations Awarded to Pfister Energy & Infinity Development 2Health News:AxoGen, Inc. to Host Surgeon Education Event at American Society for Surgery of the Hand 2014 Annual Meeting 2Health News:AxoGen, Inc. to Host Surgeon Education Event at American Society for Surgery of the Hand 2014 Annual Meeting 3Health News:Drought Solutions Overlook Too Many Factors Water Policy Expert Warns Sharon Kleyne 2Health News:Drought Solutions Overlook Too Many Factors Water Policy Expert Warns Sharon Kleyne 3
... men after bypass surgery, according to a new study done ... say whether the //results are due to medical or psychosocial ... outcomes after bypass surgery than men. Most have attributed this ... generally older, sicker, and have fewer social supports. In this ...
... is when symptoms have lasted for less than three ... self-management program that includes group classes, exercise sheet handouts, ... manage their back pain. ,Researchers from Indiana University ... low back pain. The program focuses on boosting confidence ...
... study shows hydrotherapy, or water exercise, may improve strength and ... studied more than 100 patients with osteoarthritis who were older ... first group exercised three times a week in a swimming ... did not exercise at all. Both the water and gym ...
... may improve strength and mobility in patients with osteoarthritis.// ... who were older than age 50. Patients were divided into ... in a swimming pool, the second exercised in a gym, ... water and gym programs focused on resistance exercises. ,Results ...
... lasted for less than three months. ,A new study ... sheet// handouts, and telephone follow-up calls may help patients ... from Indiana University developed a self-management program for poor, ... on boosting confidence in order to increase their motivation ...
... reducing the signs of aging in the neck. The procedure involves ... reduce the saggy appearance of the neck. Researchers say this new ... are often changes in the neck and face including the loss ... of fat in the neck. This causes the skin to sag. ...
Cached Medicine News:
... For the quantitative determination ... human serum. Progesterone ... the principle of competitive ... the test specimen and ...
... AutoDELFIA Insulin kit is for the ... and heparin plasma using the AutoDELFIA ... used in the investigation, diagnosis and ... blood glucose level). The analytical sensitivity ...
ELISA for the detection of Insulin....
ELISA for the detection of 17a OH Progesterone....
Medicine Products: