Navigation Links
Study Results Show Epratuzumab Provided Clinically Meaningful Reduced Disease Activity in Patients With Lupus
Date:10/27/2008

Encouraging Clinical Data Presented at American College of Rheumatology (ACR) meeting Show Reduced Need for Concomitant Corticosteroid Therapy

SAN FRANCISCO, Oct. 27 /PRNewswire-FirstCall/ -- UCB (Euronext Brussels: UCB) announced data from two randomized controlled trials showing that treatment with epratuzumab a humanized anti-CD22 antibody, resulted in clinically meaningful reduced disease activity, improved health-related quality of life (HRQoL) measurements and reduced reliance on corticosteroids compared to placebo treatment in patients with active moderate and severe systemic lupus erythematosus (SLE). These findings were presented at the American College of Rheumatology (ACR) annual meeting here today.

"Given the debilitating effect lupus has on a patient's quality of life, these results are encouraging," commented lead study investigator Daniel J. Wallace, M.D., Clinical Professor of Medicine, David Geffen School of Medicine, UCLA. "In these trial results, treatment with epratuzumab demonstrated clinically meaningful improvement in patients' flares and significant decrease in steroid use, which is critical given their long-term adverse effects."

"While medical advances have improved the lives and survival of people with lupus, effective therapeutic options remain limited," said Sandra C. Raymond, President and Chief Executive Officer of the Lupus Foundation of America. "It has been nearly five decades since a new treatment was approved for this devastating and life altering disease and current treatments are limited with adverse effects though recent research efforts to find new treatments are encouraging for the millions of people around the world living with lupus."

In the combined studies, beginning at week 4 and continuing through week 48, Total BILAG* scores, a clinical measure of lupus disease activity, in both epratuzumab treatment arms (360 or 720mg/m2) remained lower than placebo. Among study participants who comp
'/>"/>

SOURCE UCB
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
4. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
5. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
6. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
7. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
8. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
9. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
10. MacroGenics Begins Global Phase 2/3 Protege Study in Recent-onset Type 1 Diabetes Mellitus
11. Sarasotas Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/3/2015)... March 3, 2015  Columbia Laboratories, Inc. (Nasdaq: ... "the Company"), a specialty pharmaceutical company focused on pharmaceuticals ... at the 27th Annual ROTH Conference, which will take ... in Dana Point, California . Management,s ... 9:00 a.m. Pacific Time (12:00 p.m. Eastern Time) in ...
(Date:3/3/2015)... 03, 2015 Research and Markets ... the "Global Ultrasound Equipment Market 2015-2019" ... The Global Ultrasound Equipment market to grow ... 2014-2019 Ultrasound equipment are used to ... are extensively used by cardiologists, radiologists, surgeons, obstetricians, ...
(Date:3/3/2015)... , March 3, 2015  Cyberonics, Inc. (NASDAQ: ... for the treatment and management of epilepsy, today announced ... on Wednesday, March 11, 2015, in Miami ... President and Chief Executive Officer, will speak at 1:05 ... a fireside chat format, and no formal materials will ...
Breaking Medicine Technology:Global Ultrasound Equipment Market 2015-2019: Rise in Number of MI Diagnostic Procedures with GE Healthcare, Phillips Healthcare, Siemens Healthcare & Toshiba Medical Systems Dominating 2
(Date:3/3/2015)... (PRWEB) March 03, 2015 On February ... into the fabulous EcoLuxe Lounge, a day-long event that ... socially conscious products and services. Organized by Debbie Durkin ... and film placement producer, the EcoLuxe Lounge saw many ... of roles on General Hospital, The Flash, Star Trek: ...
(Date:3/3/2015)... March 03, 2015 Man, Woman & ... to help find cures and ensure access to treatments ... life for patents and their families. Through this annual ... in the fight for a world without blood cancers. ... fundraisers in the country, to be announced this summer. ...
(Date:3/3/2015)... In March, 1% for the Planet , one of ... campaign, “Know Your Source,” which calls for consumers to pledge ... quest for ingredient awareness and better business practices. 1% for ... partners, including King Arthur Flour, Good Culture, Farm Aid, and ... food as an environmental issue, with a focus on knowing ...
(Date:3/3/2015)... (PRWEB) March 03, 2015 While it ... the primary reason why young Canadian drivers are signing ... a greater value proposition to be enticed. Due to ... in a very stripped-back form. Its full capability ... Europe where tracking, predictive maintenance, emergency breakdown services are ...
(Date:3/3/2015)... Today is International Ear Care Day, ... occasion to applaud and promote the launch of Make ... Organization (WHO) for stemming the threat of noise-induced hearing ... people to practice safe listening when they recreate, be ... sporting events, or engaging in other forms of entertainment. ...
Breaking Medicine News(10 mins):Health News:Hollywood Star Chase Masterson and Choices Recovery Discuss Substance Abuse and Treatment at 2015 Oscars 2Health News:The Leukemia & Lymphoma Society’s Oregon and SW Washington Chapter Kicks Off Their Eleventh Annual Man, Woman & Student of the Year Campaign 2Health News:The Leukemia & Lymphoma Society’s Oregon and SW Washington Chapter Kicks Off Their Eleventh Annual Man, Woman & Student of the Year Campaign 3Health News:1% For the Planet Asks Consumers to “Know Your Source” 2Health News:TU-Automotive: Wawanesa Insurance to Discuss How UBI Can Produce Happy, Loyal Customers 2Health News:ASHA Applauds Launch of New WHO Campaign 2
... the Bradley Hasbro Children's Research Center (BHCRC) and Brown ... She said that // those who have high self-esteem ... have their asthma symptoms interfere with school. These children ... and facing asthma symptoms were associated with fewer school ...
... mystery surrounding the leaf extract of Ginkgo biloba ... ,Anticancer Research journal (Jan-Feb) features the study. ... extract before and after implanting human breast or ... receptor associated with invasive cancer. ,An ...
... discoveries related to pollutants in fishes have dissuaded many a ... been said that its benefits are much // more than ... annual meeting of the American Association for the Advancement of ... and others that make many types if fish unfit for ...
... department said that there is a sudden rise in the death ... // According to the latest figures MRSA is now six times ... in National Health Service (NHS) hospitals. A total of 1,168 people ... of death or a contributory factor in 2004, a rise of ...
... disease could due to ineffective functioning of a weak ... immune system could be responsible // for this chronic ... large intestines. The following finding has been revealed by ... ,The researchers compared the immune response of ...
... announced that they are staring human trials for testing the ... for both HIV/AIDS as well as hepatitis B. The chemical, ... called Inula britannic, has worked on HIV as well as ... Academy of Military Medical Sciences. ,"If clinical experiments ...
Cached Medicine News:Health News:Mystery unfolds about the Ginkgo biloba extract! 2Health News:Indulge in sea food: no need to worry as benefits heavier than risks! 2Health News:Rise in Deaths Rates Due To MRSA 2Health News:Viagra Offers Hope In Treatment Of Crohn’s Diseas 2
ELISA kit for Varicella-zoster IgM....
ELISA kit for Varicella-zoster IgG....
The DSL-05-10-VZM Varicella Zoster IgM Enzyme-Linked Immunosorbent Assay (ELISA) kit provides materials for the determination of IgM-class antibodies to Varicella Zoster Virus in human serum. This as...
... Scientific, Inc. Mumps IgG ELISA test system ... Mumps IgG antibody in human serum. When ... of this test, together with other clinical ... immune status, and/or aid in the diagnosis ...
Medicine Products: