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Study Reported Tadalafil Taken Once Daily Improved Erectile Function in Men with ED and Sexual Quality of Life in Couples
Date:5/6/2009

Data Published in May Issue of Journal of Sexual Medicine

INDIANAPOLIS, May 6 /PRNewswire-FirstCall/ -- Eli Lilly and Company (NYSE: LLY) today announced results from a double-blind, placebo-controlled study which showed that tadalafil 5 mg dose taken once daily was generally well-tolerated, improved erectile function for men with erectile dysfunction (ED) and reported improvement in the sexual quality of life scores for men and their female partners. The 12-week study monitored 342 men and their partners, using several scientific questionnaires to assess changes in erectile function and sexual quality of life before and after treatment with a tadalafil once daily dose. The study appears in the May issue of the peer-reviewed Journal of Sexual Medicine.

"This is the first study of tadalafil 5 mg once daily dose in the treatment of men with ED in which the female partner reported improvement in sexual quality of life scores," said lead investigator Eusebio Rubio-Aurioles M.D., Ph.D. "The sexual quality of life scores also improved among males being treated. In addition, this study showed that daily dose of tadalafil is effective and generally well tolerated in the treatment of erectile dysfunction."

Study Findings

The 16-week double-blind, multicenter, randomized study followed 342 men with a minimum three-month history of ED, as well as their female partners who had adequate sexual function as measured by the Female Sexual Function Index (FSFI). Male candidates were excluded from the study if they: 1) had previously used tadalafil; 2) experienced ED as a result of other primary sexual disorders or related surgeries; 3) had a history of other medical conditions or treatments that could negatively impact erectile or cardiovascular function; or 4) had found other phosphodieste
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SOURCE Eli Lilly and Company
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