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Study Published in European Radiology Further Supports the Use of Hologic's Breast Tomosynthesis in Cancer Screening in Practices Using Double Reads
Date:4/16/2013

BEDFORD, Mass., April 16, 2013 /PRNewswire/ -- Hologic, Inc. (Hologic or the Company) (NASDAQ: HOLX), a leading developer, manufacturer and supplier of premium diagnostics, medical imaging systems and surgical products dedicated to serving the healthcare needs of women, today announced that a new study published online in advance of print by European Radiology supports the use of breast tomosynthesis in combination with 2-dimensional (2D) imaging in breast cancer screening programs using independent double reading with arbitration.

The study, "Prospective Trial Comparing Full-field Digital Mammography (FFDM) versus Combined FFDM and Tomosynthesis in a Population-based Screening Programme Using Independent Double Reading with Arbitration," was led by Per Skaane, M.D., Ph.D. of Oslo University Hospital Ullevaal. [1] The analysis included a total of 12,621 screening examinations of women participating in the Oslo Tomosynthesis Screening Trial. In double reading, two radiologists independently read the same case and if the radiologists disagree on the diagnosis, there is an arbitration or consensus meeting where the final diagnosis of the case is decided. Double reading has been shown to increase cancer detection and is the standard method used for interpretation of mammograms for most countries outside of the U.S. with organized population-based screening programs. This study compares double reading of 2D mammography with double reading of 2D mammography plus tomosynthesis.

The researchers used Hologic's breast tomosynthesis cancer screening technology and found:

  • Tomosynthesis-based screening was successfully implemented in a large prospective screening trial. 
  • Double reading of tomosynthesis-based examinations significantly reduced false-positive interpretations. False-positive interpretations were decreased
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  • SOURCE Hologic, Inc.
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