Navigation Links
Study Links the Risk of Hypogonadism in Men to Long Acting Opioids in Patients Using Daily Opioid Therapy for Chronic Noncancer Pain
Date:2/24/2012

PALM SPRINGS, Calif., Feb. 24, 2012 /PRNewswire-USNewswire/ -- Results were presented today from the first study to show that the daily use of long-acting opioids increases the risk of hypogonadism (low testosterone) in men when compared to those taking short-acting opioids. These results were reported today at a poster session at the American Academy of Pain Medicine's 28th Annual Meeting.

Although this was a small retrospective study, Dr. Rubinstein believes this higher rate of hypogonadism shows that there may be some safety considerations that we were not aware of 10 years ago. "There has been a movement over the last 10 to 15 years to convert patients to long-acting opioids from short-acting opioids with the idea that they were more effective and less risky," comments Dr. Rubinstein. "This is the first study that calls into question whether or not there is a safety difference between long-acting and short-acting opioids."

Andrea Rubinstein, M.D., of the Department of Anesthesiology and Chronic Pain, Kaiser Permanente Santa Rosa Medical Center, in Santa Rosa, California, in collaboration with the Division of Research, presented the results. Since the 1970s hypogonadism in men has been linked to men using daily opioid therapy, but to date, no one has evaluated whether the risk of hypogonadism was linked to specific opioids, the duration of action of the opioid, or total daily opioid use. A small retrospective cohort study of 81 men, between the ages of 18 and 80 was conducted with men that were referred by primary care to the tertiary pain clinic. These men were on a stable dose of daily opioids for at least 90 days, and none had a previous diagnosis of hypogonadism. The study excluded patients with any known endocrine disease other than stable, treated hypothyroidism, or those with a prior diagnosis of cancer or HIV. Kaiser Foundation Research Institutional Review Board approved the study with waiver of consent.

The morning testosterone
'/>"/>

SOURCE American Academy of Pain Medicine
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. First Patient Screened in CSL Behring Global Phase I/III Study of Recombinant Single-Chain Factor VIII
2. Preclinical Study Examines Use of nContacts Technology in Enabling a Percutaneous Device Approach to Epicardial Ablation
3. CHPA Responds to Prescription Mandate Cost Implications Outlined in Oklahoma Economic Impact Study
4. Medical Device Study Examines Use of Emerging Markets and Outsourcing for Clinical Activities
5. Debiopharm and Curis Announce Initiation of Phase Ib Expansion Study of HSP90 Inhibitor Debio 0932
6. Uroplasty Announces Enrollment of First Patients in the CONFIDeNT Clinical Study for Treatment of Fecal Incontinence with Urgent® PC
7. Understand the Lessons Learned from the FDA QbD Pilot Programme - Case Study Merck Serono
8. SCOLR Pharmas Partner to Commence Bioequivalence Study of Ondansetron
9. Avanir Pharmaceuticals Announces Publication of Phase III Study Results Showing Efficacy and Safety of AVP-923 in the Treatment of Diabetic Neuropathic Pain
10. Zimmer and ISTO Technologies Announce Phase III Clinical Study to Evaluate the Effectiveness of Engineered Juvenile Cartilage to Repair Damaged Knees
11. Aria Diagnostics Announces Name of New Non-Invasive Prenatal Assay - Harmony Prenatal Test™ - and Publication of Study on Specimen Transport
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... 24, 2014  Kinex Pharmaceuticals announced the receipt of ... KX2-391 Ointment for the commencement of a Phase I ... third IND to be allowed by the US FDA ... a synthetic, orally active and highly selective inhibitor of ... the induction of p53, G2/M arrest of proliferating cell ...
(Date:7/24/2014)... 2014 Consolidated Net Profit increased by 43.65 ...   , India Business grew by 20.87% to Rs. ... 4,886.70 Mn Rest of World (ROW) Business grew by ... by 34.53% to Rs. 977.26 Mn Latin America Business ... Glenmark Pharmaceuticals Limited, the research-led global integrated pharmaceutical company, today ...
(Date:7/24/2014)... 2014 Boston Children,s Hospital,s Global Pediatric Summit ... feature an "Innovation Tank" – a forum designed to ... their business or product solution to a panel of ... how to accelerate the innovation and bring it to ... Friday, October 31, will be moderated by Daymond ...
Breaking Medicine Technology:Kinex Pharmaceuticals Announces Allowance of the Investigational New Drug (IND) application for KX2-391 Ointment by the United States Food and Drug Administration (FDA) 2Kinex Pharmaceuticals Announces Allowance of the Investigational New Drug (IND) application for KX2-391 Ointment by the United States Food and Drug Administration (FDA) 3Kinex Pharmaceuticals Announces Allowance of the Investigational New Drug (IND) application for KX2-391 Ointment by the United States Food and Drug Administration (FDA) 4Glenmark's Consolidated Revenue Increases by 20.08% to Rs. 14,869.40 Mn for Q1 FY 14 - 15 2Glenmark's Consolidated Revenue Increases by 20.08% to Rs. 14,869.40 Mn for Q1 FY 14 - 15 3Glenmark's Consolidated Revenue Increases by 20.08% to Rs. 14,869.40 Mn for Q1 FY 14 - 15 4Taking on Tomorrow to Feature "Innovation Tank" Pitch Opportunity for Aspiring Pediatric Health Care Entrepreneurs 2Taking on Tomorrow to Feature "Innovation Tank" Pitch Opportunity for Aspiring Pediatric Health Care Entrepreneurs 3
... July 12, 2011 Vapotherm, a privately held manufacturer of ... that it has signed a new exclusive distribution agreement with ... Korea for the Vapotherm acute care product line. ... Hippo to bring high flow therapy to the Korean market," ...
... 12, 2011 UBM TechInsights, the leader in technical ... announced today that medical devices industry veteran Bill Betten ... Devices.  In this role Mr. Betten will draw upon ... medical device sector maximize the effectiveness of the product ...
Cached Medicine Technology:Vapotherm Announces New Exclusive Distribution Agreement with Hippo Medical for South Korea 2UBM TechInsights Hires Medical Devices Industry Veteran Bill Betten 2
(Date:7/25/2014)... Tampa, FL (PRWEB) July 25, 2014 ... launches their innovative toothbrushes with antibacterial silver that naturally kill ... land on the brush. , A toothbrush is the ... diseases, dental health and hygiene, however, it is subject to ... the air. , There are more bacteria in the mouth ...
(Date:7/24/2014)... 2014 Dr. Henry H. Ting, a ... has been appointed senior vice president and chief quality ... his new role, he will oversee the hospital's clinical ... successfully led quality initiatives and interprofessional teams at the ... for the Door-to-Balloon Alliance, a collaboration of more than ...
(Date:7/24/2014)... to light at night, which shuts off nighttime production ... to tamoxifen, a widely used breast cancer drug, says ... cancer researchers. The study, "Circadian and Melatonin Disruption by ... Tamoxifen Therapy in Breast Cancer," published in the journal ... that melatonin is vital to the success of tamoxifen ...
(Date:7/24/2014)... Park, NC (PRWEB) July 24, 2014 ... ethnic minorities, and low-income households are disproportionately affected ... public food safety net in the United States, ... , Under Section 743 of the Consolidated Appropriations ... Department of Agriculture's Food and Nutrition Service (FNS) ...
(Date:7/24/2014)... Monica, CA (PRWEB) July 24, 2014 ... health seriously, they must consider their own financial and ... flabby and weak marketing campaigns to the next level ... CallFire’s Cloud Call Center, IVR, Voice Broadcast, Call Tracking ... than a 98% open rate, text messages are quickly ...
Breaking Medicine News(10 mins):Health News:Silver®Care’s New Silver Antibacterial Toothbrushes Naturally Kill Oral Germs 2Health News:Silver®Care’s New Silver Antibacterial Toothbrushes Naturally Kill Oral Germs 3Health News:NewYork-Presbyterian Hospital Names New Senior Vice President for Quality and Patient Safety 2Health News:NewYork-Presbyterian Hospital Names New Senior Vice President for Quality and Patient Safety 3Health News:Total darkness at night is key to success of breast cancer therapy -- Tulane study 2Health News:Report: Vulnerable Populations Disproportionately Affected by Food Security, Despite Public Programs 2Health News:Report: Vulnerable Populations Disproportionately Affected by Food Security, Despite Public Programs 3Health News:Pump Up Your Gym’s Marketing Muscles with Mobile Marketing: CallFire's Health & Fitness Webinar Week – July 28th to August 1st 2Health News:Pump Up Your Gym’s Marketing Muscles with Mobile Marketing: CallFire's Health & Fitness Webinar Week – July 28th to August 1st 3
... that a new strain of E. coli O157was responsible for ... in Europe and Australia, but is apparently very rare in ... the laboratory from other types of E.coli O157 and this ... it,' said HPS consultant Dr John Cowden. 'It produces the ...
... In a bid to save its plummeting sales of chicken ... //The campaign would ensure that the customers get ... been planned by McDonald’s Corp., of Oakbrook, Ill. , ... ensure that is a epidemic and bird flu scare spread ...
... study that was published in Urology Journal BJUI International has ... and almost half of 19-year-olds who have a problem are ... the Chinese University of Hong Kong and the Prince of ... questionnaires surveying children who were aged 5 to 19. The ...
... popular drug for depression has been studied by researchers, in ... from the Cold Spring Harbor Laboratory// in Long Island, New ... immature brain cells. ,This could pave the way ... Alzheimer's. The researchers, as part of their study, analyzed proteins ...
... 2007, cigarette packets will carry graphic representations depicting the dangerous ... ward off the smoking habit. The pictorial representation could be ... womb. ,A website installed by the Department of Health, ... range of pictures that intend to underline the pitfalls of ...
... is a private company and was set up in 1994 in ... accepted to provide health care facility// free of cost to NHS ... General Practitioners for 7,000 patients and employ 3 doctors and 7 ... in London. ,The deal has been signed by ...
Cached Medicine News:
Sealing tape, slightly stiffer than Polyolefin tape....
Amplification Tape 96 featuring 3M adhesive technology. Good optical quality. Minimal autofluorescence. Certified RNase and DNase free....
Aluminum Seal, Reflective, Bulk...
PVC Sealing Tape, 100/Box...
Medicine Products: