Navigation Links
Study Links the Risk of Hypogonadism in Men to Long Acting Opioids in Patients Using Daily Opioid Therapy for Chronic Noncancer Pain
Date:2/24/2012

PALM SPRINGS, Calif., Feb. 24, 2012 /PRNewswire-USNewswire/ -- Results were presented today from the first study to show that the daily use of long-acting opioids increases the risk of hypogonadism (low testosterone) in men when compared to those taking short-acting opioids. These results were reported today at a poster session at the American Academy of Pain Medicine's 28th Annual Meeting.

Although this was a small retrospective study, Dr. Rubinstein believes this higher rate of hypogonadism shows that there may be some safety considerations that we were not aware of 10 years ago. "There has been a movement over the last 10 to 15 years to convert patients to long-acting opioids from short-acting opioids with the idea that they were more effective and less risky," comments Dr. Rubinstein. "This is the first study that calls into question whether or not there is a safety difference between long-acting and short-acting opioids."

Andrea Rubinstein, M.D., of the Department of Anesthesiology and Chronic Pain, Kaiser Permanente Santa Rosa Medical Center, in Santa Rosa, California, in collaboration with the Division of Research, presented the results. Since the 1970s hypogonadism in men has been linked to men using daily opioid therapy, but to date, no one has evaluated whether the risk of hypogonadism was linked to specific opioids, the duration of action of the opioid, or total daily opioid use. A small retrospective cohort study of 81 men, between the ages of 18 and 80 was conducted with men that were referred by primary care to the tertiary pain clinic. These men were on a stable dose of daily opioids for at least 90 days, and none had a previous diagnosis of hypogonadism. The study excluded patients with any known endocrine disease other than stable, treated hypothyroidism, or those with a prior diagnosis of cancer or HIV. Kaiser Foundation Research Institutional Review Board approved the study with waiver of consent.

The morning testosterone
'/>"/>

SOURCE American Academy of Pain Medicine
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. First Patient Screened in CSL Behring Global Phase I/III Study of Recombinant Single-Chain Factor VIII
2. Preclinical Study Examines Use of nContacts Technology in Enabling a Percutaneous Device Approach to Epicardial Ablation
3. CHPA Responds to Prescription Mandate Cost Implications Outlined in Oklahoma Economic Impact Study
4. Medical Device Study Examines Use of Emerging Markets and Outsourcing for Clinical Activities
5. Debiopharm and Curis Announce Initiation of Phase Ib Expansion Study of HSP90 Inhibitor Debio 0932
6. Uroplasty Announces Enrollment of First Patients in the CONFIDeNT Clinical Study for Treatment of Fecal Incontinence with Urgent® PC
7. Understand the Lessons Learned from the FDA QbD Pilot Programme - Case Study Merck Serono
8. SCOLR Pharmas Partner to Commence Bioequivalence Study of Ondansetron
9. Avanir Pharmaceuticals Announces Publication of Phase III Study Results Showing Efficacy and Safety of AVP-923 in the Treatment of Diabetic Neuropathic Pain
10. Zimmer and ISTO Technologies Announce Phase III Clinical Study to Evaluate the Effectiveness of Engineered Juvenile Cartilage to Repair Damaged Knees
11. Aria Diagnostics Announces Name of New Non-Invasive Prenatal Assay - Harmony Prenatal Testâ„¢ - and Publication of Study on Specimen Transport
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... R.I. , July 10, 2014 CVS Caremark ... board of directors has approved a quarterly dividend of $0.275 ... dividend is payable on August 1, 2014, to holders of ... CVS Caremark is dedicated to helping people ... pharmacy company in the United States . ...
(Date:1/15/2014)... Markets ( http://www.researchandmarkets.com/research/6k27gw/dental ) has announced the addition of ... Size, Share, Growth, Trends And Forecast, 2013 - 2018" ... http://photos.prnewswire.com/prnh/20130307/600769 ) Dental consumables ... to treat dental impairments, for tooth restoration and in ...
(Date:1/15/2014)... Jan. 15, 2014 Massachusetts General Hospital (MGH), ... AMGN ) announced today that they have launched ... new therapeutic targets and develop novel therapies for ... affects millions worldwide. The MGH-Broad-Amgen collaboration brings together ...
Breaking Medicine Technology:Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 2Dental Consumables Market - Global Industry Analysis, Size, Share, Growth, Trends And Forecast, 2013 - 2018 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 2Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 3Mass. General, Broad Institute and Amgen Will Work to Discover New Drugs for Inflammatory Bowel Disease 4
... NEW YORK, Jan. 12, 2011 InstaCare Corp. ... prescription and non-prescription diagnostics, home testing products for ... direct to patient diabetes programs, and a leading ... technologies, today announced that the company,s Board of ...
... 2011 At the 29th Annual J.P. Morgan Healthcare Conference, ... that based on a preliminary review of 2010 results, it ... more than $3.5 billion compared to 2009. Adjusted cash earnings ... the midpoint of the company,s latest forecast of $3.37 to ...
Cached Medicine Technology:InstaCare Corp. Announces 2011 Genstrip Guidance Report Penned by William Walling, CFA 2Watson Announces Preliminary Financial Performance for FY 2010 2Watson Announces Preliminary Financial Performance for FY 2010 3Watson Announces Preliminary Financial Performance for FY 2010 4
(Date:7/10/2014)... "Mississippi baby" an infant seemingly cured of HIV that was ... HIV infection in The New England Journal of Medicine ... than two years of not taking antiretroviral therapy without evidence ... involved in the case. , "Certainly, this is ... medical staff involved in the child,s care, and the HIV/AIDS ...
(Date:7/10/2014)... For those students looking to bump up their grade ... spending more time in a library or study hall, ... research shows that students who were members of the ... their freshman and sophomore years had higher GPAs than ... that students with memberships stayed in school longer. An ...
(Date:7/10/2014)... of medical imaging far outweigh the risks when children ... The Right Radiation Dose. However, overuse and misuse of ... leading a collaborative effort to ensure a national protocol ... the Journal of Patient Safety , calls for ... Intersociety Accreditation Commission, and the Centers for Medicare & ...
(Date:7/10/2014)... Many studies have shown that more severe illness and ... a secondary respiratory infection after developing influenza. Now, however, ... has determined that if you reverse the order of ... pneumococcus) may actually protect against a bad case of ... bacterial protein pneumolysin, which is described as a bacterial ...
(Date:7/10/2014)... the human brain operates much the same whether active ... a better understanding of schizophrenia, bipolar disorder and other ... million Americans. , In newly published research in the ... at the Center for Molecular and Behavioral Neuroscience, determined ... rest is basically the same as that of a ...
Breaking Medicine News(10 mins):Health News:'Mississippi Baby' now has detectable HIV, researchers find 2Health News:'Mississippi Baby' now has detectable HIV, researchers find 3Health News:Want a higher GPA in college? Join a gym 2Health News:Mayo Clinic calls for standardization of safe imaging protocols for children 2Health News:Bacterial colonization prior to catching the flu may protect against severe illness 2Health News:Working to loosen the grip of severe mental illness 2
... such as high blood sugar and insulin, and low ... predict whether a woman will develop diabetes during a ... the current issue of the American Journal of ... of all women before pregnancy, particularly overweight women, could ...
... at Chicago are the first to use brain imaging ... function in children with pediatric bipolar disorder or attention ... the October issue of the Journal of the ... PBD and ADHD are very severe developmental disorders that ...
... has been the subject of many studies since its ... unclear picture of XMRV,s role in human disease. In ... of The Journal of Infectious Diseases , now ... XMRV and prostate cancer but not other links involving ...
... Nuclear Medicine (SNM) and the Society for Pediatric ... American Guidelines for Radiopharmaceutical Doses for Children. These ... by standardizing doses (based on body weight) for ... The Alliance for Radiation Safety in Pediatric Imaging ...
... HealthDay Reporter , TUESDAY, Oct. 12 (HealthDay News) -- Women ... breast cancer, even if a close relative has had the ... activity, maintaining a healthy weight and drinking alcohol in moderation, ... help protect against breast cancer in postmenopausal women, the researchers ...
... HealthDay Reporter , TUESDAY, Oct. 12 (HealthDay News) -- ... drugs such as Aredia or Zometa to reduce or delay ... the irregular heartbeat known as atrial fibrillation and for a ... of the heart beat chaotically, causing blood to pool and ...
Cached Medicine News:Health News:Metabolic status before pregnancy predicts subsequent gestational diabetes 2Health News:Brain imaging identifies differences in childhood bipolar disorder, ADHD 2Health News:New studies examine links between XMRV and human disease 2Health News:New studies examine links between XMRV and human disease 3Health News:SNM and Image GentlyTM launch initiative to standardize radiation dose in pediatric nuclear medicine 2Health News:SNM and Image GentlyTM launch initiative to standardize radiation dose in pediatric nuclear medicine 3Health News:Three Healthy Habits Cut Breast Cancer Risk, Study Finds 2Health News:Three Healthy Habits Cut Breast Cancer Risk, Study Finds 3Health News:Cancer-Fighting Bone Drugs Might Raise Stroke Risk 2Health News:Cancer-Fighting Bone Drugs Might Raise Stroke Risk 3
Storage temperature: 2 - 8C, linearity: 0 - 25 mg/dL, expected value: male: 3.5 - 7.0 mg/dL and female: 2.5 - 6.0 mg/dL. Available with calibrator and number of test 500....
Storage temperature: 15 - 30C, linearity: 0 - 20 mg/dL, expected value: male: 3.0 - 7.0 mg/dL and female: 2.2 - 6.2 mg/dL. Available with calibrator and number of tests 125....
The assay kit is for determination of uric acid in serum or urine. Wavelength: 600 nm. Linear range: up to 80 mg/dL....
Intended for the quantitative determination of uric acid in serum or plasma. Reaction: endpoint. Wavelength: 520 nm. Linearity: 20 mg/dL (1190 mol/L). Single vial, dry powder reagent....
Medicine Products: