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Study Demonstrates That AHCC(R) Provides Immune Enhancement Against the West Nile Virus
Date:9/9/2008

Proves promising for individuals living with West Nile Virus and

populations susceptible such as the elderly or immune compromised

PURCHASE, N.Y., Sept. 9 /PRNewswire/ -- A recently completed study from researchers at Colorado State University supported by the Division of Vector-Borne Infectious Diseases with the Centers for Disease Control and Prevention (CDC) has demonstrated that AHCC(R) (Active Hexose Correlated Compound) enhances host resistance by boosting protective immune responses specific to the West Nile Virus.

Since its discovery in the United States in 1999, infections caused by the West Nile Virus have become a major public health concern. West Nile Virus is caused by people being bitten by mosquitoes infected with the virus. According to the CDC, there have been 28,018 reported cases with 1,092 deaths since 1999. In 2003, the highest number of cases was reported at nearly 10,000. Currently there is no effective treatment for the disease.

The West Nile Virus study utilizing AHCC examined its effect in both young and aged mice infected with a potent strain of West Nile Virus. AHCC was administered both prior to and post infection at specific intervals. Blood was drawn and analyzed for key parameters such as IgM (Immunoglobulin M) and IgG (Immunoglobulin G) antibody levels as well as West Nile Virus-specific T cells. Increasing these responses helps the body protect itself from the virus.

Results from the study demonstrated that AHCC increased the production of West Nile Virus-specific IgM, IgG and T cells in young mice. Producing higher levels of these critical antibodies and lymphocytes is essential in helping the immune system protect itself from infection. AHCC also had an effect in aged mice but it was not as strong as on young mice. This initial study suggests that AHCC enhances protective immune responses against West Nile Virus infection in young and aged mice. Although additional studies are needed, th
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SOURCE AHCC Research Association
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