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Study Demonstrates Relationship Between Subcutaneous IgG (SCIg) Dosage and Clinical Outcomes With Hizentra® Treatment in Patients With Primary Immunodeficiencies
Date:3/21/2011

dy. "A decrease in infection rate ultimately can reduce a patient's need for antibiotics, hospitalization and missed days from work or school."

"Along with these clinical benefits, Hizentra offers patients a concentrated subcutaneous Ig therapy that they can administer in any setting that is convenient for them," said Lynne Powell, CSL Behring Senior Vice President, North America Commercial Operations. "Hizentra is another example of the commitment CSL Behring has made to understand and respond to the needs of patients who have primary immune deficiency and certain other rare health conditions."

Local reactions to infusion and treatment-related adverse events were more commonly reported with the higher dose of SCIg, however, those reactions were primarily mild to moderate in severity. The potential for increased non-serious adverse events in patients taking the higher dose SCIg should be considered when individual treatment decisions are made.

About Primary ImmunodeficienciesPrimary immunodeficiency (PI) is a group of more than 150 diseases that affect the cells, tissues and proteins of the immune system.(3) In people with PI, the immune system is either absent or functioning inadequately, leaving them more susceptible to infection.(4) For individuals with PI – many of them children – infections may not improve with treatment as expected, and may keep returning. As a result, patients may face repeated rounds of antibiotics or be hospitalized for treatment. Repeated infections can lead to organ damage, which, over time, can become life-threatening. Collectively, PIs affect an estimated 10 million people worldwide, and the incidence is estimated to be 1 in 10,000.(5) For more information on PI, please visit www.cslbehring.com or contact the leading PI patient advocate groups in the U.S., the Immune Deficiency Foundation and the '/>"/>

SOURCE CSL Behring
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