Navigation Links
Study Data Show INTUNIV™ (guanfacine) Extended Release Tablets Co-administered With Stimulants Provided ADHD Symptom Improvement in Children and Adolescents
Date:5/21/2010

tudy, no unique adverse events were observed with INTUNIV given with stimulant compared with those reported with either treatment alone.  The most commonly reported treatment emergent adverse events (TEAEs) among patients treated with INTUNIV and a stimulant (greater than or equal to 5 percent) were headache, somnolence, upper respiratory tract infection, fatigue, insomnia, upper abdominal pain, dizziness, decreased appetite, cough, irritability, and nausea.  The most commonly reported TEAEs among patients in the placebo/stimulant group were headache, upper respiratory tract infection, and irritability.  The majority of TEAEs were mild to moderate in severity.   The rate of discontinuation due to TEAEs was 2.7 percent in the INTUNIV AM/stimulant group, 3.9 percent in the INTUNIV PM/stimulant group, and 0.7 percent in the placebo/stimulant group.  There were three serious adverse events reported among study participants (including one report of syncope) and all were considered unrelated to study drug.  No deaths occurred during the study.

"Shire is committed to ADHD and continues to develop a range of ADHD treatments for health care providers and patients," said Michael Yasick, Senior Vice President of Shire's ADHD Business Unit.  "We are pleased with the results of this trial and are currently working with the FDA to secure an indication for use of INTUNIV with stimulants in the treatment of ADHD."  

This study was supported by funding from Shire Development Inc.  Dr Timothy Wilens was a speaker and received grant support from and is a consultant for Shire.  

*Suboptimal response was defined as treatment with a stable dose of stimulant for at least four weeks with improvement, yet persistence of mild to moderate ADHD symptoms (defined as an ADHD-RS-IV total score of at least 24 an
'/>"/>

SOURCE Shire plc
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. Amsterdam Molecular Therapeutics Reports Promising Data From Cholesterol Lowering Gene Therapy Study
2. New Prime Therapeutics Study Finds Antiviral Medications Were Not Hoarded During H1N1 Flu Season
3. New Study Shows ENJUVIA® Significantly Reduced Sleep Time Awakenings Caused by Hot Flashes in Postmenopausal Women
4. ThromboGenics and BioInvent to Receive EUR10 Million Milestone as Partner Roche Begins New Clinical Study with TB-403
5. Whistleblower Lawyers Comment on New England Journal of Medicine Study
6. Medco Study: Despite FDA Warnings, Nearly One-Third of Asthma Patients Still Treated with Long-Acting Beta Agonists Without Controller Medications, Increasing Their Risk for Complications and Hospitalizations
7. QRxPharma Successfully Completes Comparative Phase 1 Proof-of-Concept Study for MoxDuo(R) CR Tablet Formulation
8. QRxPharma Releases Additional Pivotal Phase 3 Combination Rule Study Data for MoxDuo(R)IR in Patients with Post-Surgical Pain
9. Spiral Enteroscopy is Three Times Faster than Double-Balloon Enteroscopy in Diagnosing the Small Intestine, New Study Finds
10. SARcode Corporation Announces Phase 2 Study Results of SAR 1118 Topical Ophthalmic Solution for the Treatment of Dry Eye
11. BetterInvesting Magazine Releases Julys Stock to Study and Undervalued Stock Choices for Investors Informational and Educational Use
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... , Nov. 26, 2014  Genomic Health, Inc. (Nasdaq: ... , Chairman, Chief Executive Officer and President, will participate ... Conference at The New York Palace Hotel in ... at 11:30 am Eastern Time (ET). To ... conference call, go to the  Investor Relations  section of ...
(Date:11/26/2014)... , November 26, 2014 Investor-Edge ... VVUS ), Horizon Pharma PLC (NASDAQ: ... and Johnson (NYSE: JNJ ), and Theravance Inc. ... companies can be accessed at: http://investor-edge.com/register . ... 4,758.25, up 0.07%, the Dow Jones Industrial Average edged 0.02% ...
(Date:11/26/2014)... 2014  CARsgen, a leader in the development of ... a variety of cancers, today announced the completion of ... China -based healthcare private equity fund.   ... the development of new therapeutics for liver, lung, stomach ... and Shanghai Renji Hospital, the company plans to initiate ...
Breaking Medicine Technology:Genomic Health to Present at the 26th Annual Piper Jaffray Healthcare Conference 2Genomic Health to Present at the 26th Annual Piper Jaffray Healthcare Conference 3Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 2Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 3Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 4Pharma Stocks Highlight - VIVUS, Horizon Pharma, Endocyte, Johnson and Johnson, and Theravance 5CARsgen Completes Series A Financing 2
... cell company,Neuralstem, Inc., (Amex: CUR ) announced ... a European patent EP0915968, covering the,"Isolation, Propagation and ... Central Nervous System of Mammals." The European patent,has ... Germany,Ireland, Spain, Sweden, Switzerland and the United Kingdom., ...
... In Migraine Pain ... 48 Hours Vs. Placebo, MENLO PARK, Calif., April ... from a clinical study of the company,s,novel investigational intranasal ... The placebo-controlled proof of concept study evaluated the ...
Cached Medicine Technology:Neuralstem Announces Issuance of Core Technology Patent in Europe 2ROXRO PHARMA Announces Positive Clinical Proof of Concept Results for Novel Intranasal Migraine Treatment 2ROXRO PHARMA Announces Positive Clinical Proof of Concept Results for Novel Intranasal Migraine Treatment 3
(Date:11/28/2014)... Mabel’s Labels , the market ... an award-winning company established by four moms, today announced ... Tricia Mumby have been honored with a 2014 RBC ... PROFIT Award for Excellence in Entrepreneurship. , All 4 ... Mumby) accepted the award on behalf of Mabel’s Labels ...
(Date:11/28/2014)... 28, 2014 UniWigs.com, a leader in the wig ... Friday to the next Monday. This promotion features: , ... 40 items up to 70% off (no coupon code needed), ... > Free shipping on orders over $49 , Visit http://www.uniwigs.com ... days from Nov. 28th to Dec. 1st and the first 100 ...
(Date:11/28/2014)... (PRWEB) November 28, 2014 "Most of my ... me to use crutches," said an inventor from Findlay, Ohio. ... convenient way to support my foot, which inspired me to ... to offer a convenient way to support an injured foot. ... around. It eliminates the need for crutches. The design redistributes ...
(Date:11/28/2014)... November 28, 2014 Before that Thanksgiving meal ... preparing for the Christmas shopping season. Today, people will stand ... Black Friday, the biggest retail shopping day of the year. ... electronic device, New Albany dentist Dr. Ronald Receveur ... improve oral health and literally brighten a few smiles. , ...
(Date:11/28/2014)... 2014 Most of the people attending a ... at Lake Prince Woods retirement community found out ... sentimental value but wouldn’t have made the cut to be ... his expertise in decorative and folk art and his appearances ... about trends in buying and selling antiques. Broadly speaking ...
Breaking Medicine News(10 mins):Health News:Mabel's Labels’ Co-Founders Named A Winner In The 2014 RBC Canadian Women Entrepreneur Awards Program; A Second-Time Win For The Brand 2Health News:Mabel's Labels’ Co-Founders Named A Winner In The 2014 RBC Canadian Women Entrepreneur Awards Program; A Second-Time Win For The Brand 3Health News:Pre-X'mas Crazy Sale Starts from $0 at UniWigs.com 2Health News:New Albany Dentist Offers Gift Ideas That Can Improve Oral Health 2Health News:New Albany Dentist Offers Gift Ideas That Can Improve Oral Health 3Health News:New Albany Dentist Offers Gift Ideas That Can Improve Oral Health 4Health News:Antiques Appraiser Sheds Light on "Treasures" 2
... Effective Means to Provide Health Care Access to Millions ... The National Patient Advocate Foundation (NPAF) - a national, ... of improved patient access to health care through public ... announced this month the election of four new Executive ...
... possibility of remote monitoring for chronically ill patients will ... and Australia have devised a decentralized system to avoid ... a forthcoming issue of the International Journal of ... range of chronic illnesses, including diabetes, high blood pressure, ...
... Health Care Reform, Received More Industry Contributions Than ... and pharmaceutical manufacturers contributed $5.5 million to the ... House of Representatives during the last two election ... reform dominated political discourse, according to the nonprofit, ...
... Petfinder.com and Merial Team Up to Ensure Animal Welfare ... 9 Petfinder.com, the largest online database of adoptable ... generators to 500 shelters and rescue groups nationwide with ... to the Paws program, a disaster preparedness initiative launched ...
... with chemo and radiation , , MONDAY, March 9 ... chemotherapy drug temozolomide and radiotherapy increases survival for glioblastoma ... improvement persists for up to five years, say Swiss ... aggressive form of primary brain tumor. For more than ...
... DALLAS, March 9 Inspired by Beryl Co-Founder Barry Spiegelman ... The Beryl Institute is hosting the second annual ... at Sky Creek Ranch Golf Club in Keller, Texas. To ... the tournament will be presented to UCLA,s Neuro-Oncology Program, ...
Cached Medicine News:Health News:National Patient Advocate Foundation Announces 2009 Elections of Health Policy Leaders to Executive Board of Directors 2Health News:National Patient Advocate Foundation Announces 2009 Elections of Health Policy Leaders to Executive Board of Directors 3Health News:National Patient Advocate Foundation Announces 2009 Elections of Health Policy Leaders to Executive Board of Directors 4Health News:National Patient Advocate Foundation Announces 2009 Elections of Health Policy Leaders to Executive Board of Directors 5Health News:National Patient Advocate Foundation Announces 2009 Elections of Health Policy Leaders to Executive Board of Directors 6Health News:National Patient Advocate Foundation Announces 2009 Elections of Health Policy Leaders to Executive Board of Directors 7Health News:National Patient Advocate Foundation Announces 2009 Elections of Health Policy Leaders to Executive Board of Directors 8Health News:Peer-to-peer heart monitoring 2Health News:Consumer Watchdog: Health Insurers & Drug Companies Contributed $5.5 Million to Top 10 Senate and House Recipients Since 2005 2Health News:Consumer Watchdog: Health Insurers & Drug Companies Contributed $5.5 Million to Top 10 Senate and House Recipients Since 2005 3Health News:Consumer Watchdog: Health Insurers & Drug Companies Contributed $5.5 Million to Top 10 Senate and House Recipients Since 2005 4Health News:Consumer Watchdog: Health Insurers & Drug Companies Contributed $5.5 Million to Top 10 Senate and House Recipients Since 2005 5Health News:Petfinder.com Foundation 'Rescues' 500 Shelters and Rescue Groups Nationwide with $1 Million Worth of Generators 2Health News:Combo Treatment for Aggressive Brain Tumor May Lengthen Life 2Health News:Think About It. Barry Spiegelman Memorial Golf Classic Benefits Brain Cancer Research 2
20 g MVR knife. Dimensions: 31.8 mm x 1.18 mm x 2.7 mm....
Full Handle Laseredge Spoon Blade Knife, 3.0 mm angled double bevel. Blade dimension: 11.0 mm (L) x 3.0 mm (W). Cut: 320....
Full Handle Laseredge Slit Blade Knife, 3.2 mm angled double bevel. Blade tip dimension: 14.4 mm x 3.2 mm x 4.0 mm....
Full Handle Laseredge Slit Blade Knife, 3.0 mm angled bevel up. Blade tip dimension: 14.4 mm x 3.0 mm x 3.7 mm....
Medicine Products: