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Study Data Show CUVPOSA® Reduced Chronic Severe Drooling in Patients Ages 3-16 Years-Old with Neurologic Conditions
Date:1/25/2012

t 1-800-FDA-1088 or www.fda.gov/medwatch.

About Cerebral Palsy

Cerebral palsy is a lifelong condition that encompasses a group of non-progressive, neurological disorders affecting body movement and muscle coordination.  About 10-30 percent of children with cerebral palsy suffer from excessive drooling.(1)

About Chronic Severe Drooling

Sialorrhea (drooling or excessive salivation) is an unintentional loss of saliva from the mouth.(1)  Drooling is normal in infants, but a significant proportion of the developmentally disabled population experiences drooling caused primarily by neuromuscular dysfunction that makes it hard to swallow. 

About Shionogi & Co., Ltd.

Headquartered in Osaka, Japan, Shionogi & Co., Ltd. is a major research-driven pharmaceutical company dedicated to placing the highest value on patients.  Shionogi's Research and Development currently targets three therapeutic areas: Infectious Diseases, Pain, and Metabolic Syndrome.  The Company has provided such innovative medicines as Crestor and Doripenem, which have been successfully delivered to millions of patients.  In addition, Shionogi is engaged in new research areas such as allergy and cancer.  Contributing to the health of patients around the world through development in these therapeutic areas is Shionogi's primary goal.  For more details, please visit http://www.shionogi.co.jp/index_e.html.  For more information on Shionogi Inc., headquartered in Florham Park, NJ, please visit www.shionogi.com

Forward Looking Statements 

This announcement contains forward-looking statements. These statements are based on expectations in light of the information currently available, assumptions that are subject t
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