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Study Confirms Soy Isoflavones Reduce Menopausal Hot Flashes
Date:4/4/2012

alleviating hot flashes. Since there is often a large placebo effect, women taking supplements with the right soy isoflavone profile will likely see at least a 50 percent reduction compared to doing nothing."

Though many different isoflavones exist in nature, the three found in soy are genistein, daidzein and glycitein. According to the authors of the study, isoflavone supplements providing higher amounts of genistein were approximately 50 to 200 percent more potent at reducing hot flash frequency than isoflavone supplements containing lower amounts of genistein.

"Supplements providing a total of 50 mg of total isoflavones will be effective as long as they also provide at least 19 milligrams of genistein," said Mark Messina, Ph.D, soy expert, industry consultant and contributing author to the study.

"We are pleased that such a thorough evaluation of the most well-conducted studies showed that soy isoflavones are highly effective for the alleviation of hot flashes," said Steve O'Brien, product manager of Natural Health and Nutrition at ADM. "To maximize relief, ADM's NovaSoy brand soy isoflavones reflect the same profile of isoflavones naturally present in soy, including higher amounts of genistein."

"Hot flashes are one of the most common symptoms of menopause," added Messina. "For women with moderate-to-severe hot flashes who are seeking relief from symptoms, the reduction in the number and severity of hot flashes observed in our analysis in response to soy isoflavones will likely result in a significant improvement in quality of life."

A meta-analysis is a statistical analysis of a large number of studies for the purpose of integrating the findings. Of the 17 studies included in the meta-analyses, 13 trials (including 1,196 women) evaluated hot flash frequency, and nine trials (including 988 women) evaluated hot flash severity.

The analysis was conducted by Kyoko Taku, Ph.D, MD (National Institutes of Health, Japan); Melb
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SOURCE Archer Daniels Midland Company
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