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Study Confirms Limited Human-To-Human Spread of Avian-Flu Virus in Indonesia in 2006
Date:8/28/2007

pplication called TranStat, which will allow first responders to enter, store and perform real-time analysis of data from infectious-disease outbreaks. This tool soon will be available online free of charge via MIDAS, the Models of Infectious Disease Agent Study, which is supported by the National Institute of General Medical Sciences.

"We know the key to preventing a pandemic is early detection, containment and mitigation with antiviral therapy and this tool will enable those on the front lines, such as physicians, epidemiologists and other public-health officials, to carry that out efficiently," Halloran said. "The manuals on how to collect the necessary data are decades old. They are very outdated and incomplete. Often people on the front lines don't know what to do; they don't collect the correct data to assess whether transmission is occurring. TranStat will prompt people to gather precisely the data that needs to be collected to better understand and contain any infectious-disease spread, not just the avian flu," Sugimoto said.

If a smoldering disease cluster does flame out of control, the software also could be used to estimate the important characteristics of the virus -- such as its transmissibility, secondary-attack rate and reproductive number -- which would give public-health officials a better chance at slowing its spread until a vaccine or other effective control measures could be implemented.

Yang and colleagues recently described the basis for the statistical methods used in the research in The Annals of Applied Statistics.

The study was funded and supported by the National Institute of General Medical Sciences MIDAS network and the National Institute of Allergy and Infectious Diseases.

Longini and Halloran also are professors of biostatistics and Sugimoto is a pre-doctoral student in the School of Public Health and Community Medicine at the University of Washington.

At Fred Hutchinson Cancer Research Center, our i
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SOURCE Fred Hutchinson Cancer Research Center
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