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Study Confirms Efficacy of Innovative Therapies' Quantum Negative Pressure Wound Therapy (NPWT) in Enhancing Wound Healing
Date:12/5/2013

POMPANO BEACH, Fla., Dec. 5, 2013 /PRNewswire/ -- In the first randomized, controlled study to compare the efficacy of NPWT with and without simultaneous irrigation, researchers found that NPWT with or without irrigation reduced the wound size at a far greater rate than the control therapy. In addition, results showed NPWT with simultaneous irrigation further reduced the amount of bioburden compared to wounds treated with NPWT alone.

The study, recently published in the November-December issue of Wound Repair and Regeneration, also analyzed the effects of different irrigation solutions on wound healing and bioburden reduction. Normal saline and Polyhexanide biguanide, commonly known as the antimicrobial Prontosan®, were evaluated as irrigant solutions and both improved bioburden over NPWT alone. Interestingly, normal saline was found just as effective as using the antimicrobial, Prontosan.  

"Our preclinical research affirmed our hypothesis that irrigation therapy is both an effective tool for wound healing and reducing bioburden. What makes this data so exciting from a clinical perspective is that irrigation therapy showed such dramatic results in healthy pigs, which are highly resistant to infection. These results are likely understating the full healing potential of irrigation therapy for chronic wounds in patients with multiple comorbidities," said Kathryn Davis, PhD, Department of Plastic Surgery, University of Texas Southwestern Medical Center and the lead author of the study. "The results beg for more clinically focused research and we're looking forward to putting our methodology to the test in a clinical trial in the coming months."

For the study, researchers established a rigorous porcine methodology where full thickness excisional wounds were placed on six different p
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SOURCE Innovative Therapies, Inc.
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