Navigation Links
Study Confirms Effectiveness of Innovative Prism Glasses For Hemianopia Patients
Date:5/19/2009

Suggests additional training to help brain adapt more fully and further enhance benefits

BOSTON, May 19 /PRNewswire-USNewswire/ -- In a study of specially designed peripheral prism glasses for hemianopia patients (blinded in half the visual field in both eyes), scientists found that two-thirds of patients continued to wear the glasses at the end of the study period and beyond, indicating a high level of success. They also found that the brains of patients had not fully remapped to adjust for the prisms, which means that improved training in their use could further enhance the benefits, says principal investigator, Dr. Eli Peli, a senior scientist at Schepens Eye Research Institute and inventor of the glasses.

The study, published in the May 2009 issue of Optometry and Vision Science, not only reaffirms previous clinical studies, but also adds a deeper understanding of the neurological processes at play when a patient uses prisms for this purpose, adds Peli.

More than a million Americans suffer from hemianopia, which blinds the vision in one half of the visual field in both eyes -- the result of strokes, tumors or trauma. Hemianopia patients are often unaware of what they cannot see and frequently bump into walls, trip over objects or walk into people on the side where the visual field is missing.

The prisms, attached above and below the center of a spectacle lens in Peli's invention, shift images from one side of the visual field to the other side and alert patients to objects and obstacles not otherwise visible to them. Alerted to the existence of these objects, patients turn to look, or, if their brains are fully adapted (remapped), perceive quickly where the objects are and automatically avoid them without turning their eyes and head. (In earlier designs by other scientists, the prism was in the middle of the lens and caused double vision.)

"The best case scenario," says Peli, "is for a patient to be able to make rapid decisions based on the perception rather than moving their heads when an unseen object is detected."

Peli and his team asked 28 patients with complete hemianopia to wear the peripheral prism glasses as much as possible for the duration of the study, which averaged about nine weeks. Success was measured by continued wear, visual field expansion, perceived direction (caused by brain remapping), and perceived improvement in quality of life.

The research team found that 67 percent of patients chose to continue to wear the glasses at the end of the study. They also found that all patients had expansion of their visual field of about 22 degrees and expressed reduced difficulty in noticing and avoiding obstacles. On the other hand, only two patients demonstrated even an intermittent adaptation to the change in visual direction produced by the peripheral prism glasses, which means that no patient had remapped his or her brain to automatically make the perceptual adjustment.

Based on these results, Dr. Peli and his team plan to conduct future research that will examine the best way to train patients to reprogram their brains to perceive direction automatically.

The research team consisted of Mr. Robert Giorgi and Drs. Russell Woods and Eli Peli, all of the Schepens Eye Research Institute.

This study was conducted with a prototype of the glasses, on which the prisms are temporarily applied. There are now permanent prism glasses available, which continue to be studied and perfected in on-going multi-center trials.

Patients interested in trying the peripheral prism glasses can contact Chadwick Optical for referral to a doctor in their area. Go to http://www.chadwickoptical.com/ for contact information.

Schepens Eye Research Institute is an affiliate of Harvard Medical School and the largest independent eye research institute in the nation.


'/>"/>
SOURCE Schepens Eye Research Institute
Copyright©2009 PR Newswire.
All rights reserved

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
4. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
5. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
6. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
7. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
8. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
9. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
10. MacroGenics Begins Global Phase 2/3 Protege Study in Recent-onset Type 1 Diabetes Mellitus
11. Sarasotas Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... Research and Markets has announced the ... Tests" report to their offering. ... The World Market for Companion Diagnostics covers the ... analysis in the report includes the following: ... Kits) by Region (N. America, EU, ROW), 2015-2020 , ...
(Date:6/24/2016)... Belgium , June 24, 2016 /PRNewswire/ ... announced the appointment of Dr. Edward Futcher ... a Non-Executive Director, effective June 23, 2016.Dr. Futcher ... and Nominations and Governance Committees.  As a non-executive ... provide independent expertise and strategic counsel to VolitionRx ...
(Date:6/23/2016)... , June 23, 2016 Research ... Devices Global Market - Forecast to 2022" report to ... the treatment method for the patients with kidney failure, it ... excess fluid from the patient,s blood and thus the treatment ... potassium and chloride in balance. Increasing number ...
Breaking Medicine Technology:
(Date:6/27/2016)... ... 27, 2016 , ... TopConsumerReviews.com recently awarded their highest five-star rating to Best ... individuals in the United States and Canada wear eyeglasses. Once considered to be a ... and make a fashion statement. Even celebrities use glasses as a way of creating ...
(Date:6/26/2016)... ... ... Brent Kasmer, a legally blind and certified personal trainer is helping to develop a weight ... app plans to fix the two major problems leading the fitness industry today:, ... program , They don’t eliminate all the reasons people quit their exercise program ...
(Date:6/25/2016)... ... June 25, 2016 , ... "With 30 hand-drawn hand gesture ... said Christina Austin - CEO of Pixel Film Studios. , ProHand Cartoon’s package ... Final Cut Pro X . Simply select a ProHand generator and drag it ...
(Date:6/25/2016)... Montreal, Canada (PRWEB) , ... June 25, 2016 , ... ... the pursuit of success. In terms of the latter, setting the bar too high ... low, risk more than just slow progress toward their goal. , Research from ...
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association ... it will receive two significant new grants to support its work to advance ... 25th anniversary by recognizing patients, medical professionals and scientists for their work in ...
Breaking Medicine News(10 mins):