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Studies Report Nocturia Was Associated With Risk of Death and Represented a Significant Economic Burden to U.S. Society
Date:6/1/2010

ell as falls," said Jeffrey P. Weiss, M.D., FACS, Professor and ACGME Program Director in the Department of Urology at SUNY Downstate Medical School. "This common condition is often under-diagnosed and misunderstood by the medical community and should be taken more seriously."

Increased Mortality Risk in Younger Adults

Data from the U.S. Third National Health and Nutrition Examination Survey (NHANES III) indicated that nocturia was a predictor of mortality, more so in relatively younger people than in the elderly. Adjustments for co-morbid conditions that are associated with nocturia, including heart disease, diabetes and obesity, only partially explained the increased mortality.  Analyses were conducted on a sample of 15,988 men and women age 20 and older from the NHANES III national probability survey conducted between 1988 and 1994, with mortality data obtained by linkage of NHANES III to death certificate data from the National Death Index through December 31, 2000. In the NHANES III survey, nocturia was assessed by the question, 'How many times a night do you usually get up to urinate?' The overall prevalence of nocturia, defined as two or more episodes of urination per night, was found to be 15.5% among men and 20.9% among women, and increased rapidly with age.(1) Multivariate analyses showed men and women with two or more night-time urinations had a statistically significant trend towards increased mortality; when the analyses were done by age groups, there was a greater association with mortality risk among adults aged 64 or younger.

These analyses were supported through an unrestricted educational grant to New England Research Institutes, Inc. from Ferring Pharmaceuticals.

Increased Mortality Risk in the Elderly


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SOURCE Ferring Pharmaceuticals Inc.
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