Navigation Links
Studies Investigate New Methodologies to Improve Recovery and Survival Strategies for Patients Undergoing Hematopoietic Cell Transplantation
Date:12/10/2011

ells taken from the bone marrow.

PBSCs are stem cells originally found in the bone marrow that have been moved, or mobilized, into the blood stream by a special drug regimen. Unlike bone marrow stem cells, which must be extracted from the bones in an operating room, PBSCs are more easily obtained through apheresis, a process similar to regular blood donation, which collects the PBSCs through a tube inserted in a vein. A critical step before the transplant is to find a donor that is tissue matched to the recipient.

About one-third of patients who need a PBSC or bone marrow transplant for treatment of a blood disease have a matched, related donor. According to the National Marrow Donor Program, of the 70 percent who cannot find a donor within their family, most will be able to find an unrelated donor. Since the majority of transplant patients ultimately receive cells from unrelated donors, there is a need to better understand the risks associated with transplants of unrelated donor cells.

Previous clinical trials on related donor transplants have demonstrated that PBSC transplants in patients with leukemia and other blood diseases result in better engraftment, lower relapse rates, and increased survival compared to transplants with bone marrow stem cells. However, those trials also found that PBSC transplants carry an increased risk of GVHD, a serious and often deadly post-transplant complication that occurs when the newly transplanted donor cells recognize the recipient's own cells as foreign and attack them. Patients who survive early post-transplant may develop chronic GVHD, a disabling condition managed with long-term immunosuppressant therapy.

Many transplant centers are increasingly using PBSCs as a source for adult stem cells because of their superiority in clinical trials that have directly compared outcomes between PBSCs and bone marrow stem cells from related donors. However, to date, there has not been a comparative study of the
'/>"/>

SOURCE American Society of Hematology
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11

Related medicine technology :

1. Bayers Drospirenone-containing Combination Oral Contraceptives: FDA Advisory Committees Affirm Positive Benefit-risk Profile and Recommend an Update of Labels to Reflect Information From Available Studies
2. Genomic Health Announces Presentation of Sixteen Oncotype DX Studies at the 2011 CTRC-AACR San Antonio Breast Cancer Symposium
3. Montage Announces Three More Hospitals Implement Their On-Demand Search and Data Mining Technology for Radiology Studies
4. Sustained Viral Response from Phase 2 Studies of BI 201335, Including Difficult-to-Treat HCV Patient Types
5. Isis Initiates Phase 1 Studies with Isis-GCGRRx and Isis-GCCRRx to Treat Type 2 Diabetes
6. Data From Phase 2 Clinical Studies of Telotristat Etiprate in Patients With Carcinoid Syndrome to be Presented at North American Neuroendocrine Tumor Society Meeting
7. New Clinical Studies Presented at the American Society of Anesthesiologists Annual Meeting Show Benefits of Masimo Noninvasive Technologies: SpHb, PVI, RRa, and SEDLine
8. Inovio Pharmaceuticals and VGX International to Advance Therapeutic Hepatitis C and Hepatitis B Synthetic Vaccines into Clinical Studies
9. Managing Bioequivalence Studies to Optimize the Quality, Cost, and Speed of Generics Manufacturing
10. FDA Seeks Comment on Proposed Guidelines for High-Quality Clinical Studies
11. Urgent® PC Clinical Studies Results Scheduled for Presentation at International Continence Society
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... 2014  Come fall, many children, teenagers, and even ... want to be for Halloween. And, a number of ... contact lenses bought without a prescription. Halloween, ... purchase and wear contact lenses without a prescription. According ... consumer survey, 17 percent of Americans have worn ...
(Date:9/30/2014)... Sept. 30, 2014 CytRx Corporation (NASDAQ: ... development company specializing in oncology, today announced the ... evaluating aldoxorubicin compared to topotecan in subjects with ... relapsed or were refractory to prior chemotherapy. Aldoxorubicin ... agent, doxorubicin. CytRx has received Orphan Drug Designation ...
(Date:9/29/2014)... and DUBLIN , Sept. ... or the "Company"), a biotechnology company pioneering the manufacturing ... of innovative therapies for cancer, HIV/AIDS, opportunistic infections and ... its shareholders from CEO Noreen Griffin The letter follows: ... (the "Company" or "TNIB") received a number of calls ...
Breaking Medicine Technology:The Spooky Truth: What You Need To Know About Contact Lens Hygiene 2The Spooky Truth: What You Need To Know About Contact Lens Hygiene 3CytRx Initiates Global Phase 2b Clinical Trial of Aldoxorubicin for the Treatment of Relapsed/Refractory Small Cell Lung Cancer 2CytRx Initiates Global Phase 2b Clinical Trial of Aldoxorubicin for the Treatment of Relapsed/Refractory Small Cell Lung Cancer 3CytRx Initiates Global Phase 2b Clinical Trial of Aldoxorubicin for the Treatment of Relapsed/Refractory Small Cell Lung Cancer 4CytRx Initiates Global Phase 2b Clinical Trial of Aldoxorubicin for the Treatment of Relapsed/Refractory Small Cell Lung Cancer 5TNI BioTech, Inc. Corporation's CEO Issues Letter to Shareholders Discussing Cytocom Dividend 2TNI BioTech, Inc. Corporation's CEO Issues Letter to Shareholders Discussing Cytocom Dividend 3TNI BioTech, Inc. Corporation's CEO Issues Letter to Shareholders Discussing Cytocom Dividend 4TNI BioTech, Inc. Corporation's CEO Issues Letter to Shareholders Discussing Cytocom Dividend 5TNI BioTech, Inc. Corporation's CEO Issues Letter to Shareholders Discussing Cytocom Dividend 6TNI BioTech, Inc. Corporation's CEO Issues Letter to Shareholders Discussing Cytocom Dividend 7TNI BioTech, Inc. Corporation's CEO Issues Letter to Shareholders Discussing Cytocom Dividend 8
... 15 Tolerx, Inc., a,biopharmaceutical company engaged in ... treatment of immune-mediated diseases, announced today,the successful completion ... a novel,humanized anti-CD4 monoclonal antibody (MAb), in subjects ... study was designed to,assess the safety, tolerability, and ...
... System Runs ,Heart Model of the Future, ... To Insight, SUNNYVALE, Calif., Jan. 15 In the quest ... Montreal (UdM) have run the largest mathematical simulation of a heart,ever ... system from SGI (Nasdaq: SGIC ). The new UdM model ...
Cached Medicine Technology:Tolerx Achieves Milestone with Completion of Phase Ib Clinical Study of TRX1 in Cutaneous Lupus Erythematosus 2Tolerx Achieves Milestone with Completion of Phase Ib Clinical Study of TRX1 in Cutaneous Lupus Erythematosus 3Universite de Montreal Researchers Simulate World's Largest Heart Model Using SGI Technology 2Universite de Montreal Researchers Simulate World's Largest Heart Model Using SGI Technology 3Universite de Montreal Researchers Simulate World's Largest Heart Model Using SGI Technology 4
(Date:9/30/2014)... 2014 All on Four dental ... persons who have received dental implants to vigilant in ... post. , The post, which can be found at ... if they don’t brush and floss diligently, they could ... their natural teeth: the bone will deteriorate and the ...
(Date:9/30/2014)... 2014 Youth Town’s annual BBQ/Music Festival ... to 2 p.m. at the Youth Town campus (3641 ... sponsors this family-oriented festival, which will offer music, food ... feature a car show, arts and crafts fair, music, ... games. Also, Lightning McQueen and Mater from the hit ...
(Date:9/30/2014)... 2014 “Biology and botany are ... Brickner, “and it’s about naming rights.” , In ... new on the Bryan William Brickner Blog, the ... Institutes of Health (PubMed). The post highlights five ... REM transitions, aging with THC, the wake-inducing effects ...
(Date:9/30/2014)... CA (PRWEB) September 30, 2014 Top10inaction.com, ... main focus on ranking and reviewing all essential categories ... has officially announced the best liquid foundation at ... Serum Foundation is named as the best foundation of ... drugstore as well as high end brands, hence customers ...
(Date:9/30/2014)... East Longmeadow, Massachusetts (PRWEB) September 30, 2014 ... Excellence’, the Wingate of East Longmeadow facility has ... new Ventilator Program that combines advanced ... staff. This program is one of the only ... this type of care. The primary focus ...
Breaking Medicine News(10 mins):Health News:All on Four Dental Implants Dentist Writes Blog on Preventing Gum Disease 2Health News:All on Four Dental Implants Dentist Writes Blog on Preventing Gum Disease 3Health News:Homeostasis: Publius’ Sleep Political Cannabinoid Science ~ New on the Bryan William Brickner Blog 2Health News:Yves Saint Laurent is Named As Best Liquid Foundation 2014 2Health News:Wingate Healthcare Announces New Ventilator Care Program at East Longmeadow Facility 2Health News:Wingate Healthcare Announces New Ventilator Care Program at East Longmeadow Facility 3
... mobile computing and medication carts unveils TX11: a mobile computing cart ... ... OH (PRWEB) November 11, 2008 -- The Columbus, OH based medical ... newest in their line of mobile computing carts : the ...
... MOUNTAIN VIEW, Calif., Nov. 11 The 2008 ... Product,Innovation of the Year Award is presented to ... suppressant ingredient -,Slimaluma - for the global weight ... action, superior quality and safety,standards of Slimaluma have ...
... 10 Ready or not, the holiday season,is here. ... turkey and pies, merry-making eggnog and potato latkes,and then ... come Super Bowl,buffalo wings and Valentine,s Day chocolates to ... non-stop holiday cooking and,feasting., Enter Helene Phillips, the ...
... Nov. 10 TeamHealth Inc.,s parent,company, Team Finance ... quarter ended September 30, 2008., The Company ... services business line and substantially completed the disposal,of ... 2007. In accordance with,relevant accounting guidance, the results ...
... Of $9 million appropriated by,the Texas legislature to ... automated external defibrillators (AEDs), $3.5 million remains,unclaimed. Texas ... purchase under,the reimbursement program until the November 14, ... by lay people with CPR training,to resuscitate victims ...
... Increased risk of stroke a major issue in analysis of ... An analysis of 33 studies on drugs known as beta ... surgical procedure other than heart surgery. In fact, using beta ... stroke, the scientists say. , The researchers who conducted the ...
Cached Medicine News:Health News:Mobile Computing Carts Leader to Release New Clinical Computer Cart 2Health News:Gencor Pacific Group Picks Up Frost & Sullivan Global Appetite Suppressant and Satiety Ingredients Product Innovation of the Year Award 2Health News:Gencor Pacific Group Picks Up Frost & Sullivan Global Appetite Suppressant and Satiety Ingredients Product Innovation of the Year Award 3Health News:Tips for Maintaining Your Physique While Enjoying Your Favorite Treats 2Health News:Tips for Maintaining Your Physique While Enjoying Your Favorite Treats 3Health News:Team Finance LLC Announces Third Quarter 2008 Results 2Health News:Team Finance LLC Announces Third Quarter 2008 Results 3Health News:Team Finance LLC Announces Third Quarter 2008 Results 4Health News:Team Finance LLC Announces Third Quarter 2008 Results 5Health News:Team Finance LLC Announces Third Quarter 2008 Results 6Health News:Team Finance LLC Announces Third Quarter 2008 Results 7Health News:Team Finance LLC Announces Third Quarter 2008 Results 8Health News:Team Finance LLC Announces Third Quarter 2008 Results 9Health News:$3.5 Million in Reimbursements for Purchases of Automated External Defibrillators (AEDs) for Texas Schools Still Unclaimed With Deadline Approaching 2Health News:Beta Blocker Use Questioned in Non-Heart Surgery 2Health News:Beta Blocker Use Questioned in Non-Heart Surgery 3
0.25 mm diameter textured tip with protective guard....
... for perfect focus where it's needed - ... along with Keeler's wide angle light beam ... patient's pupil size, you will see the ... technology provides a longer life battery and ...
... for perfect focus where it's needed - ... along with Keeler's wide angle light beam ... patient's pupil size, you will see the ... technology provides a longer life battery and ...
... individually adjusted for perfect focus where it's ... paper. This, along with Keeler's wide angle ... whatever the patient's pupil size, you will ... view. Lithium-ion technology provides a longer life ...
Medicine Products: