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Stroke Study Reveals a Key Target For Improving Treatment
Date:6/22/2008

ic brain scans and tPA treatment.

If the clinical trial in human patients in Sweden bears out the findings seen in mice, perhaps Gleevec could be given immediately upon suspicion of stroke-like symptoms, before diagnostic scans and other tests can be made to determine if a patient could benefit from tPA.

Funding for the study came from the National Institutes of Health, Ludwig Institute for Cancer Research, Karolinska Institutet, the Novo Nordisk Foundation, the Swedish Research Council, the Swedish Cancer Foundation, the LeDucq Foundation and the IngaBritt and Arne Lundberg Foundation.

The study's authors include Linda Fredriksson, Melissa Geyer, Erika Folestad, Jacqueline Cale, Johanna Andrae, Yamei Gao, Kristian Pietras, Kris Mann, Manuel Yepes, Dudley K Strickland, and Christer Betsholtz. Reference: Nature Medicine, DOI 10.1038/nm1787

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Kara Gavin

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SOURCE University of Michigan Health System
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