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Stent Grafts Top "Gold Standard" Balloon Angioplasty for Dialysis Patients
Date:2/11/2010

s that this novel therapy (stent grafts) provides clear improvement over balloon angioplasty by prolonging the function of a patient's bypass without surgery—helping individuals avoid additional invasive procedures and time in the hospital," noted Haskal, who is also professor of radiology and surgery at the University of Maryland School of Medicine. "Stent grafts overwhelmingly performed better than balloon angioplasty for maintaining access in dialysis patients, providing superior patency and freedom from repeat interventions," added the lead investigator and co-author of "Stent Graft Versus Balloon Angioplasty for Failing Dialysis-access Grafts." He noted, "What we've done is arguably supersede the results of surgery by improving the flow dynamics beyond those achievable with an operation."

Thirteen participating sites—including academic, community-based, inpatient and freestanding outpatient dialysis centers—enrolled 190 patients (69 men, 121 women) with failing arteriovenous (AV) grafts in this study, said Haskal. Ninety-seven patients received stent grafts, with 93 undergoing balloon angioplasty (percutaneous transluminal angioplasty or PTA). There were no significant differences between graft and PTA groups with respect to demographics or relevant medical history. Nearly 51 percent of dialysis accesses treated with stent grafts remained open at six months, as compared to just 23 percent of those treated with balloon angioplasties. Treating physicians had a nearly 94 percent success rate at implanting the stent grafts. There were no differences in adverse events between the two approaches.

"Interventional radiologists work to keep access to the circulatory system open to ensure that patients with end-stage renal disease can continue to receive regular life-saving dialysis," noted Society of Interventional Radiology President Brian F. Stainken, M.D., FSIR, who
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SOURCE Society of Interventional Radiology
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