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Stem Cell Sciences Announces the Creation of the World's First Authentic Rat Embryonic Stem Cells from its Exclusively Licensed Technology
Date:9/2/2008

vantage here is that rats are viewed as more predictable human models than mice for several psychiatric, neurological and cardiovascular drug targets. The ability to knock-in human genes should also enable drug metabolism studies to be undertaken with higher predictability in rats than previously available. We believe this opens the way to new and more effective drug discovery, and expect there to be considerable commercial interest in access to this exciting technology," commented Dr Alastair Riddell, Chief Executive Officer of Stem Cell Sciences.

The culture medium patent family (PCT/GB2007/001163), which is filed in multiple territories including the USA, contains several specific enzyme inhibitors, which, when used in certain combinations, can be used to grow embryonic (or pluripotent) rat stem cells reliably in a serum-free environment. The rat ES cell patent family (PCT/GB2007/002913), which is also filed in multiple territories including the USA, gives SCS the exclusive right to make and commercialise unique rat models for biopharmaceutical research and development, a global market with an estimated size in excess of US$80m.

About Stem Cell Sciences plc

Stem Cell Sciences (SCS) is an international research and development company focusing on the commercial application of stem cell biology technologies for drug discovery and regenerative medicine research. Stem Cell Sciences is now focussing on building revenues through the sale of products, collaborative research and licensing deals with international biotechnology and pharmaceutical companies.

Stem Cell Sciences has a substantial portfolio of patents and patent applications in both adult and embryonic stem cell fields. The Company has been active in the stem cell research field since 1994, principally focused on technologies to grow, differentiate, and purify adult and embryonic stem cells. These include technologies to permit the generation of highly purified stem cells and their
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