Navigation Links
Stem Cell Sciences Announces the Creation of the World's First Authentic Rat Embryonic Stem Cells from its Exclusively Licensed Technology
Date:9/2/2008

CAMBRIDGE, England, September 2 /PRNewswire-FirstCall/ --

- ("Stem Cell Sciences", "SCS", "the Company")

Stem Cell Sciences plc (AIM:STEM, ASX:STC), a company focused on the commercialisation of stem cells and stem cell technologies, is pleased to announce that two independent laboratories in the UK and USA have achieved germ-line transmission from embryonic stem (ES) cells in rats using technologies exclusively licensed to the company by Edinburgh University. This is believed to be the first time that germ-line transmission from rat ES cells has been demonstrated, and full scientific reports on this breakthrough, which has been independently verified, have been submitted to a major scientific journal for publication.

Under the terms of its agreement with Edinburgh University, SCS has global exclusive rights to commercialise the rat ES cells, the specific culture medium used to generate and grow the cells, and rats derived therefrom. The Company has exclusively licensed two important patents covering this new technology from the University and now plans to engage in confidential discussions with interested parties seeking a sublicence to use rat ES cells in their commercial drug discovery programmes.

The main advantage of this important new technology is that it allows the generation of both knock-out rat models, in which the effect of gene deletion is studied, as well as the generation of knock-in models, which involves the insertion of genes. For example, in the case of knock-out models, their response to drugs can provide information on safety and efficacy. Alternatively, the insertion of genes such as those involved in drug metabolism in the human liver means that knock-in models can provide information on human safety and pharmacokinetics.

"This remarkable breakthrough will enable the generation of transgenic rat models for drug discovery in a very similar manner to the already widely used transgenic mice models. The ad
'/>"/>

SOURCE Stem Cell Sciences plc
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Neurosciences Institute Discovers Drug Extends Stroke Treatment Time to 24 Hours, Repairs Brain Tissue
2. Human Genome Sciences Completes Enrollment in Second Phase 3 LymphoStat-B(R) Trial
3. Human Genome Sciences Completes Enrollment in Randomized Phase 2 Trial of HGS-ETR1 in Non-Small Cell Lung Cancer
4. Ardea Biosciences Advances Lead Product Candidate for the Treatment of Gout, RDEA594, Into Phase 1 Clinical Trial
5. Particle Sciences Expands Its Combination Product Capabilities
6. Ardea Biosciences Presents Phase 2a Antiviral Activity Data for Lead HIV Candidate, RDEA806 at XVII International AIDS Conference
7. Light Sciences Oncology Raises $40.1 Million in Series C Financing
8. Light Sciences Oncology Begins Clinical Trials of Litx Therapy in Patients with Enlarged Prostate
9. Sangamo BioSciences Announces Nature Biotechnology Study Demonstrating the Use of Zinc Finger Nucleases to Generate HIV Resistant T Cells
10. Ardea Biosciences Reports Additional Positive Phase 2a Results for Lead HIV Candidate, RDEA806, Demonstrating Up to 1.9 Log Reduction in Plasma Viral Load with Once-Daily Dosing
11. Pressure BioSciences, Inc. Announces $850,000 NIH SBIR Phase II Award for the Development of a New PCT-dependent System for Improved Biomarker Discovery, Diagnostics, and Drug Discovery
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... WORTH, Texas , Jan. 15, 2014  Humberto C. ... Dermatology Achievement Award" from the Journal of Drugs ... Aesthetic & Clinical Conference (ODAC). The event is January 17-20, ... Florida . The ODAC ...
(Date:1/15/2014)... is very pleased to announce the appointment of Mr. ... Mark was promoted from his current role of Chief Operating ... in Massachusetts , Mississippi ... 2012 with 20+ years of broad-based operations, sales, engineering and ...
(Date:1/15/2014)... , Jan. 15, 2014  According to Millennium ... technology market intelligence, the United States ... (TEO) device markets will expand moderately through 2022, ... segments. In particular, increasing interest in drug-eluting beads ...
Breaking Medicine Technology:Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4Tegra Medical Appoints New Chief Executive Officer 2Tegra Medical Appoints New Chief Executive Officer 3US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 2US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 3
... NEW YORK, March 14, 2011 Reportlinker.com announces ... in its catalogue: Global Cardiac ... http://www.reportlinker.com/p0240523/Global-Cardiac-Monitoring-Systems-Market-2009-2013.html With advancements in technology, ... capabilities have been introduced in the Cardiac Monitoring ...
... 2011 Reportlinker.com announces that a new market ... Hepatitis A Preventive Vaccines - Pipeline ... http://www.reportlinker.com/p0453473/Hepatitis-A-Preventive-Vaccines---Pipeline-Assessment-and-Market-Forecasts-to-2017.html Hepatitis A ... to 2017 SummaryGlobalData, the industry ...
Cached Medicine Technology:Reportlinker Adds Global Cardiac Monitoring Systems Market -2013 2Reportlinker Adds Global Cardiac Monitoring Systems Market -2013 3Reportlinker Adds Hepatitis A Preventive Vaccines - Pipeline Assessment and Market Forecasts to 2017 2Reportlinker Adds Hepatitis A Preventive Vaccines - Pipeline Assessment and Market Forecasts to 2017 3
(Date:4/23/2014)... "simple and accessible detection methods that can rapidly ... of a single cell inside that population has ... Chang Lu. , In the Royal Society of ... announced that he and his coworkers have developed ... of a protein ( Chem. Sci. , 2014, ...
(Date:4/23/2014)... 2014 Five for-profit and non-profit organizations in ... in Proof of Concept grants to accelerate maturation ... products, the Life Sciences Discovery Fund (LSDF) announced ... Program grant to the Washington Biotechnology & Biomedical ... to train the next generation of entrepreneurs and ...
(Date:4/23/2014)... prevent the depletion of self-control, according to research published ... Association for Psychological Science. , Self-control can be difficult ... attention on a boring textbook are hard things to ... difficulty: Exerting self-control for a long period seems to ... tasks. , "It is as if self-control is a ...
(Date:4/22/2014)... been shown to reduce seizures in patients with medication-resistant ... with an innovative electrode placement planning system developed by ... of seizures in nearly half of the implanted Rush ... good news for a large portion of the nearly ... seizures can,t be controlled with medications and who are ...
(Date:4/22/2014)... pregnancy among women using a newer method of planned ... greater over a 10-year period than using the more ... Yale University and UC Davis has found. , ... , the study found the higher risk of pregnancy ... name Essure. , "This study provides essential information ...
Breaking Medicine News(10 mins):Health News:Following a protein's travel inside cells is key to improving patient monitoring, drug development 2Health News:LSDF announces commercialization grants and Entrepreneur Mentoring Program 2Health News:ADHD drug may help preserve our self-control resources 2Health News:Newly approved brain stimulator offers hope for individuals with uncontrolled epilepsy 2Health News:Risk of pregnancy greater with newer method of female sterilization 2Health News:Risk of pregnancy greater with newer method of female sterilization 3
... age had an increased risk of developing high blood ... Johansson, Karolinska Institute, Stockholm reported in the Journal Circulation ... prone to high blood pressure compared to normal born ... data from 329,495 Swedish men born between 1973 and ...
... study, published in the November issue of the Journal ... in residential care can reduce their incidence of falls ... years.// ,To determine whether vitamin D supplementation can ... people in residential care who are not classically vitamin ...
... as Kyolic may decrease the risk of heart attacks ... UK scientists.// ,Dr. Khalid Rhaman and colleagues from ... of Kyolic brand aged garlic extract inhibits platelet aggregation ... clots. Clot formation inside healthy blood vessels is abnormal ...
... under 50 are more likely to die from suicide than ... // ,A study of public hospital emergency departments in ... attending the emergency departments of seven Perth hospitals between June ... committed suicide within weeks of being discharged. The sample included ...
... living organisms, are exposed to ever-changing environments, oxidative ... able to defend themselves against all these insults, ... abilities simply by ‘stealing’ genetic information from other ... of sex, known as horizontal gene transfer. ...
... (CBI) carried out simultaneous raids on some government hospital ... cities on Monday.// ,The raids were conducted in ... official of the investigating agency said., ,The houses ... and Uma Goel of Sucheta Kriplani Hospital here were ...
Cached Medicine News:Health News:Bacteria Evolve Armamentarium Against Antibiotics By ‘Stealing’ Gen 2
Auto Refkeratomoeter...
... The InfusO.R. Pump is a ... aid in the administration of ... anesthetic procedures. It provides for ... muscle relaxants, and vasoactive drugs ...
Developed to meet the infusion needs in NICU, Anesthesia and Critical Care, the AUTO SYRINGE AS50 Infusion Pump delivers precise, controlled infusions....
Pain management can be complicated. But that doesn't mean your PCA infusion system should be. The new SYNDEO PCA Syringe Pump streamlines pain therapy with a powerful combination of intelligent desig...
Medicine Products: