Navigation Links
Statins Lower Stroke Severity, Improve Recovery
Date:2/26/2009

ROCHESTER, Minn., Feb. 26 /PRNewswire-USNewswire/ -- Mayo Clinic researchers have shown that patients who were taking statins before a stroke experienced better outcomes and recovery than patients who weren't on the drug -- even when their cholesterol levels were ideal. The finding is reported in the current issue of the Journal of Stroke and Cerebrovascular Diseases.

"We were trying to determine if the daily use of statins had more of an impact on stroke patients than simply lowering their "bad" (low-density lipid) cholesterol," explains lead researcher Latha Stead, M.D. "We already knew statin use improved outcomes in general, so we focused on the patients who had optimal LDL levels and found it still had quite significant value."

Statins or reductase inhibitors are enzymes that are widely used to improve cardiovascular health and, more recently, for certain vascular conditions in the brain. One use has been to lower the level of LDL which can contribute to arterial blockages.

Significance of the Research

Previous researchers had shown a lower death rate and improved function in strokes when people had used statins. The Mayo team found that statin used in this cohort also decreased the severity of the strokes and significantly improved overall outcomes. The researchers say this shows benefits far beyond lowering lipid levels. Researchers think the specific benefits may include plaque stabilization and improved cell function in vascular walls, as well as anti-inflammatory and antioxidant factors. More research is needed to pinpoint the specific benefits.

How it was done

Researchers identified 508 patients who were diagnosed with acute ischemic stroke in the emergency department during the 22 months from March 2004 to December 2005. Among that number, 207 had their lipid levels measured within 15 days either side of the stroke incident -- and had LDL levels at or below 100 mg/dL, which is considered optimal for healthy individuals. Roughly half the cohort of 207 had been taking statins. Researchers also adjusted for age, gender and stroke severity.

Others on the research team were Lekshmi Vaidyanathan, M.B.B.S.; GautamKumar, M.B.B.S.; M. Fernanda Bellolio, M.D.; Robert Brown, Jr., M.D.; Smitha Suravaram, M.B.B.S.; Sailaja Enduri, M.B.B.S.; Rachel Gilmore, M.B.B.Ch.; and Wyatt Decker, M.D., all of Mayo Clinic.

To obtain the latest news releases from Mayo Clinic, go to www.mayoclinic.org/news. MayoClinic.com (www.mayoclinic.com) is available as a resource for your health stories. For more on Mayo Clinic research, go to www.mayo.edu.

To access web video and audio from Dr. Decker, click the link below to visit the Mayo Clinic News Blog. http://newsblog.mayoclinic.org/2009/02/26/study-shows-statins-lower-stroke-severity/


'/>"/>
SOURCE Mayo Clinic
Copyright©2009 PR Newswire.
All rights reserved

Related medicine technology :

1. Seniors Can Be Heartened by New Study on Statins
2. Abbotts Phase III Studies of Investigational TriLipix(TM) (ABT-335), in Combination With Statins, Meets Primary Endpoints on Improving LDL, Triglycerides and HDL
3. Cleveland Clinic to Lead First Head-to-Head Comparison of the Two Most Potent Statins
4. Risk of Stroke, Heart Disease in Women Lowered by Mediterranean Diet
5. AMT: Glybera(R) Lowers Pancreatitis Incidence Significantly
6. Implantable Defibrillators Lower Risk of Death in Older Heart Patients
7. Colesevelam HCl Lowered LDL Cholesterol in Pediatric Patients With Heterozygous Familial Hypercholesterolemia
8. Video: Resveratrol-based Nutriceutical (Longevinex(R)) Induces Favorable Changes on Gene Expression in Mouse Heart At Doses 17-320 Times Lower Than Prior Studies
9. Want a Reason to Love Your Lower Belly Fat? Its Rich in Stem Cells
10. Fish Oil and Red Yeast Rice Studied for Lowering Blood Cholesterol
11. Blueberry-Supplemented Diet Shows Promise in Lowering Cholesterol in Animal Trials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2016)... , May 4, 2016 BiondVax Pharmaceuticals ... Dr. Ron Babecoff , will be attending the Joseph ... . On Thursday, May 5, Dr. Babecoff ... presented by Joseph Gunner & Co, taking place ... presentation that Dr. Babecoff will be using is downloadable from ...
(Date:5/4/2016)... May 4, 2016 Valeritas Holdings, ... an alternative public offering (APO). This was accomplished via ... Valeritas, Inc. and a private placement of approximately 5 ... per share. Under the terms of the ... Valeritas Holdings, Inc. will trade on the OTC Markets ...
(Date:5/4/2016)... 4, 2016 Research ... "Global Actinic Keratosis Market and Competitive Landscape ...      (Logo: http://photos.prnewswire.com/prnh/20160330/349511LOGO ... Competitive Landscape Highlights 2016, provides comprehensive insights ... epidemiology, Actinic Keratosis market valuations and forecast, ...
Breaking Medicine Technology:
(Date:5/4/2016)... ... 04, 2016 , ... The RIDER Institute announces an IndieGoGo ... broad-spectrum antiviral therapeutics. DRACOs have proven effective against all 18 viruses tested in ... http://igg.me/at/EndTheVirus and runs for 60 days, we are raising new funding ...
(Date:5/4/2016)... ... May 04, 2016 , ... a2z, Inc. ... Society™ and Canadian Association for Enterostomal Therapy (CAET) will be utilizing powerful and ... tools to attendees and exhibitors for the 2016 WOCN Society & CAET Joint ...
(Date:5/4/2016)... ... , ... May kicked off with Melanoma Monday , a multi-agency effort ... Turner is encouraging her patients, as well as residents all around Dallas, Cleburne, Irving, ... now and in the future. , The dermatology-specific awareness month ends with “Don’t Fry ...
(Date:5/4/2016)... ... 04, 2016 , ... Recognizing that lifestyle medicine is essential to health and ... tapped David Katz, MD, MPH, president of the American College of Lifestyle Medicine, as ... is especially gratifying,” said Katz. “There is so much opportunity to add years to ...
(Date:5/4/2016)... TX (PRWEB) , ... May 04, 2016 , ... ... Nightstick all-LED multi-function small and compact tactical (6.7 inch) dual-light flashlights in models ... Las Vegas, model NSP-9842XL (average retail starting at $59.95) uses 2 included CR-123 ...
Breaking Medicine News(10 mins):