Navigation Links
Statins Lower Stroke Severity, Improve Recovery
Date:2/26/2009

ROCHESTER, Minn., Feb. 26 /PRNewswire-USNewswire/ -- Mayo Clinic researchers have shown that patients who were taking statins before a stroke experienced better outcomes and recovery than patients who weren't on the drug -- even when their cholesterol levels were ideal. The finding is reported in the current issue of the Journal of Stroke and Cerebrovascular Diseases.

"We were trying to determine if the daily use of statins had more of an impact on stroke patients than simply lowering their "bad" (low-density lipid) cholesterol," explains lead researcher Latha Stead, M.D. "We already knew statin use improved outcomes in general, so we focused on the patients who had optimal LDL levels and found it still had quite significant value."

Statins or reductase inhibitors are enzymes that are widely used to improve cardiovascular health and, more recently, for certain vascular conditions in the brain. One use has been to lower the level of LDL which can contribute to arterial blockages.

Significance of the Research

Previous researchers had shown a lower death rate and improved function in strokes when people had used statins. The Mayo team found that statin used in this cohort also decreased the severity of the strokes and significantly improved overall outcomes. The researchers say this shows benefits far beyond lowering lipid levels. Researchers think the specific benefits may include plaque stabilization and improved cell function in vascular walls, as well as anti-inflammatory and antioxidant factors. More research is needed to pinpoint the specific benefits.

How it was done

Researchers identified 508 patients who were diagnosed with acute ischemic stroke in the emergency department during the 22 months from March 2004 to December 2005. Among that number, 207 had their lipid levels measured within 15 days either side of the stroke incident -- and had LDL levels at or below 100 mg/dL, which is considered optimal for healthy individuals. Roughly half the cohort of 207 had been taking statins. Researchers also adjusted for age, gender and stroke severity.

Others on the research team were Lekshmi Vaidyanathan, M.B.B.S.; GautamKumar, M.B.B.S.; M. Fernanda Bellolio, M.D.; Robert Brown, Jr., M.D.; Smitha Suravaram, M.B.B.S.; Sailaja Enduri, M.B.B.S.; Rachel Gilmore, M.B.B.Ch.; and Wyatt Decker, M.D., all of Mayo Clinic.

To obtain the latest news releases from Mayo Clinic, go to www.mayoclinic.org/news. MayoClinic.com (www.mayoclinic.com) is available as a resource for your health stories. For more on Mayo Clinic research, go to www.mayo.edu.

To access web video and audio from Dr. Decker, click the link below to visit the Mayo Clinic News Blog. http://newsblog.mayoclinic.org/2009/02/26/study-shows-statins-lower-stroke-severity/


'/>"/>
SOURCE Mayo Clinic
Copyright©2009 PR Newswire.
All rights reserved

Related medicine technology :

1. Seniors Can Be Heartened by New Study on Statins
2. Abbotts Phase III Studies of Investigational TriLipix(TM) (ABT-335), in Combination With Statins, Meets Primary Endpoints on Improving LDL, Triglycerides and HDL
3. Cleveland Clinic to Lead First Head-to-Head Comparison of the Two Most Potent Statins
4. Risk of Stroke, Heart Disease in Women Lowered by Mediterranean Diet
5. AMT: Glybera(R) Lowers Pancreatitis Incidence Significantly
6. Implantable Defibrillators Lower Risk of Death in Older Heart Patients
7. Colesevelam HCl Lowered LDL Cholesterol in Pediatric Patients With Heterozygous Familial Hypercholesterolemia
8. Video: Resveratrol-based Nutriceutical (Longevinex(R)) Induces Favorable Changes on Gene Expression in Mouse Heart At Doses 17-320 Times Lower Than Prior Studies
9. Want a Reason to Love Your Lower Belly Fat? Its Rich in Stem Cells
10. Fish Oil and Red Yeast Rice Studied for Lowering Blood Cholesterol
11. Blueberry-Supplemented Diet Shows Promise in Lowering Cholesterol in Animal Trials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/12/2017)... EXTON, Pa. , Oct. 12, 2017 ... global leader in innovative solutions for injectable drug administration, ... results before the market opens on Thursday, October 26, ... discuss the results and business expectations at 9:00 a.m. ... 877-930-8295 (U.S.) or 253-336-8738 (International). The conference ID is ...
(Date:10/10/2017)... , Oct. 10, 2017  NDS received FDA 510(k) clearance in ... medical-grade battery-powered display stand specifically designed for endoscopy environments. An innovative ... into a clinical solution to support the improvement of patient outcomes, ... Design ... Solution ...
(Date:10/4/2017)... , Oct. 4, 2017  According to the Centers for Disease ... end of October . PhysicianOne Urgent Care is helping communities across ... Westchester, NY , by offering no-cost* flu shots through the end ... mandated by certain health insurance regulations. ... The best time to get a flu shot is by the end ...
Breaking Medicine Technology:
(Date:10/13/2017)... ... , ... As health professionals work to improve their approach to healthcare, there ... more than filling out a survey; in many cases health professionals and patients are ... care and research on the importance of active engagement with patients and members of ...
(Date:10/13/2017)... ... 13, 2017 , ... PurhealthRX , a leading Health and Nutrition Company, ... Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing CBD market by ... be easily incorporated into liquid products, while reducing costs to end users. , The ...
(Date:10/13/2017)... ... October 13, 2017 , ... Many families have long-term insurance that covers care ... have a waiver for care if the client has a cognitive impairment diagnosis. ... for care, is often waived, so the benefits from their insurance start immediately,” said ...
(Date:10/13/2017)... (PRWEB) , ... October 13, 2017 , ... Yisrayl Hawkins, ... week that explains one of the most popular and least understood books in the ... cryptic and puzzling descriptions that have baffled scholars for centuries. Many have tossed it ...
(Date:10/13/2017)... ... October 13, 2017 , ... “America On The Brink”: the Christian history ... The Brink” is the creation of published author, William Nowers. Captain Nowers and ... WWII veteran, he spent thirty years in the Navy. Following his career as ...
Breaking Medicine News(10 mins):