Navigation Links
Start of Phase I Study for Intranasal Pandemic Influenza Vaccine deltaFLU
Date:7/8/2008

VIENNA, Austria, July 8 /PRNewswire/ -- Avir Green Hills Biotechnology starts a clinical phase I study with its intranasal vaccine deltaFLU against pandemic influenza. This novel generation of a live-attenuated vaccine based on the deletion of the NS1 gene has shown superior preclinical data. In taking this step, the Viennese biotech company sets yet another milestone in the development of effective and safe vaccines.

Aim of Phase I Study

The randomized, double-blind phase I study of the pandemic vaccine deltaFLU will be run at the Department of Clinical Pharmacology, Medical University of Vienna. The aim of phase I study is to analyze the safety and efficacy of the vaccine in healthy volunteers.

Preclinical Data, Pandemic Vaccine

"Our vaccine lacks the pathogenicity factor NS1. Due to this deletion, the vaccine is likely to show a superior safety profile. We are confident that the pandemic deltaFLU vaccine will be tolerated even at high doses," comments Thomas Muster, founder and CEO/CSO of Avir Green Hills Biotechnology.

Outstanding preclinical data show an excellent immune response even against distantly related pandemic H5 strains (cross-protection). Moreover, a long lasting immune response - an important prerequisite for an effective vaccine - was observed.

"We are very pleased about the success of our vaccine in the preclinical studies. The data are superb and exceed our highest expectations," reports Andrej Egorov, who is Vice President for Research at Avir Green Hills Biotechnology and one of the leading experts in the field of live attenuated influenza vaccines.

The novel influenza vaccine deltaFLU

differs from a conventional influenza vaccine in three major characteristics and in the method of production:

1. Nasal Spray

The vaccine is administered intranasally with a spray device instead of being injected into a muscle. This approach offers the major advantage of stimulating the v
'/>"/>

SOURCE Avir Green Hills Biotechnology Trade AG
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. BN ImmunoTherapeutics Starts Clinical Trials With Prostate Cancer Vaccine
2. InterMune Announces Start of 14-Day Triple Combination Study of ITMN-191 in Patients With Chronic Hepatitis C
3. Impliant Restarts Pivotal Clinical Trial for Patented TOPS(TM) Spine System
4. TriLink Awarded a Phase II Grant for a Second Hot Start PCR Project
5. Starting Flu Vaccination in August Could Help Protect Nearly 11 Million More Children During Scheduled Doctors Visits
6. MedImmune Advances Asthma Program with Start of a Phase 2 Trial in Europe and Australia and First U.S.-Based Clinical Trial for Antibody Targeting IL-13
7. Diamyd(R) Diabetes Vaccine Receives Approval to Start Phase III Trials in Europe
8. VIDEO: Femara(R) helps protect against return of breast cancer even when treatment starts several years after completing tamoxifen therapy
9. Michael J. Fox Foundation Awards Up to $3 Million to Industry Teams to Jumpstart Promising PD Drug Development
10. Pharmion and MethylGene Start Phase 2 Combination Clinical Trial With MGCD0103 and Vidaza(R) in Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma
11. GlaxoSmithKline and Theravance Announce Start of Large Phase 2B ICS and LABA Studies for Asthma in the Horizon Program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... 2014 Yesterday, former Congressman Patrick ... manufacturing facility. Rep. Kennedy and Dick Moberg ... cutting-edge research in neurological disease and treatment. ... advocate, Garen Staglin , created One Mind, ... changes that will radically accelerate the development and ...
(Date:7/10/2014)... --  Ventana Medical Systems, Inc.  (Ventana), a member of ... an agreement with Merck KGaA, Darmstadt, Germany ... the United States and ... division on the development and commercialization of a companion ... diagnostic assays. In alignment with Merck KGaA,s strategic approach ...
(Date:7/10/2014)... July 10, 2014 CVS Caremark Corporation (NYSE: ... has approved a quarterly dividend of $0.275 (27.5 cents) per ... on August 1, 2014, to holders of record on July ... CVS Caremark is dedicated to helping people on their path ... the United States . Through the company,s ...
Breaking Medicine Technology:Representative Patrick Kennedy visits Moberg's medical device facility to discuss improvement in brain injury care 2Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 2Ventana Medical Systems, Inc. and Merck KGaA, Darmstadt, Germany to develop companion diagnostic test for cancer treatment 3
... The Thompson Group of Companies announced today that ... a Hamilton Sundstrand Corporation business. AIT will be organized ... terms of the purchase were not disclosed. ... marketing of process analytical instruments including Analect FTIR, PIONIR ...
... Healthcare Diagnostics announces two new three-year agreements with Novation ... chemistry and microscopy systems, and for microbiology systems and ... VHA and University HealthSystem Consortium (UHC) member organizations and ... The members served by Novation have access to ...
Cached Medicine Technology:Thompson Group Acquires Hamilton Sundstrand's Applied Instrument Technologies 2Novation® Awards Siemens as Single Source for Urine Chemistry and Microbiology Systems and Tests 2
(Date:7/12/2014)... Texas (PRWEB) July 12, 2014 ... Breastfeeding Made Simple as a valuable new resource for ... roughly two-thirds of American women work away from their ... sources touting the benefits of breastfeeding, but often feel ... to nurse their babies. With its evidence-based insights, and ...
(Date:7/12/2014)... Restore My Vision Today is a ... a couple boasting very impressive credentials on the field ... Today as a way to help consumers do without ... their respective patients’ treatments . , In ... trove of pertinent information relevant to eye care like:, ...
(Date:7/12/2014)... West Palm Beach, FL (PRWEB) July 12, 2014 ... wide variety of high-quality peptides that are used solely ... online. To honor two successful years in business, Maxim ... Performance LLC, has just launched a new and updated ... addition, the research blog section has been updated with ...
(Date:7/12/2014)... doesn't matter what your budget is, the trendy wedding gowns ... gown can visit Discount-Dress.com (a reliable online store ... Recently, the company has announced its new selection of ... is also providing great discounts for these unique items. All ... promotion is July 29, 2014. , Discount-Dress.com is a ...
(Date:7/11/2014)... (PRWEB) July 12, 2014 Recently, DressyQuinceanera.com, ... 200 Quinceanera Dama dresses to its online ... items are offered at deeply discounted rates, up to ... from DressyQuinceanera.com are equally excellent in terms of quality ... carefully handmade. Similar discounts are also offered for the ...
Breaking Medicine News(10 mins):Health News:Praeclarus Press Announces the Release of Working and Breastfeeding Made Simple by Nancy Mohrbacher, A Much Needed Resource For Today's Working Mothers 2Health News:Restore My Vision Today | Groundbreaking Book Reveals How To Restore Your Vision Without The Use of Glasses – Vinamy 2Health News:Restore My Vision Today | Groundbreaking Book Reveals How To Restore Your Vision Without The Use of Glasses – Vinamy 3Health News:Maxim Peptide Celebrates Second Anniversary Online with an Updated Website and Special Deals Section 2Health News:Worldwide Brides-to-be: It Is Time To Show Your Beauty By Wearing A Trendy Summer Short Wedding Dress From Discount-Dress.com 2Health News:DressyQuinceanera.com: Beautiful Quinceanera Dama Dresses At Low Prices 2
... of Pennsylvania School of Medicine have found an ... kidney transplants and complications during the first week ... MD, PhD, Professor of Pathology and Laboratory Medicine ... Laboratory, and Harold Feldman MD, MSCE, Professor of ...
... SAN DIEGO, Nov. 25 Gen-Probe Incorporated,(Nasdaq: GPRO ... 20th,Annual Piper Jaffray Health Care Conference on Tuesday, December 2, ... webcast live and may be,accessed through a link on the ... will be available for 30 days following,the event. , ...
... but women lagging behind men, study finds , , TUESDAY, Nov. ... allocation system that gives preference to patients with the greatest ... disparities among those waiting for new livers are narrowing. , ... become too sick for a transplant while on the waiting ...
... Nationwide Health Properties, Inc. (NYSE: NHP ) is ... nursing home property company that may be in default on ... similarity of the names, it wanted to clarify that the ... Nationwide Health Properties, Inc. is a real estate ...
... The Pharmacy Technician Certification Board,s (PTCB) Executive Director and CEO, ... Leadership Award, the highest annual honor given by the National ... Corrigan,s innovative leadership in developing, implementing, and researching programs or ... ...
... Citizens Republic Bancorp has,selected HealthPlus Insurance Company to become ... effective January 1, 2009. , ... Wisconsin, and Iowa, will be offered an array of PPO ... "HealthPlus is an outstanding provider of health insurance which like,Citizens, ...
Cached Medicine News:Health News:Understanding donor-recipient genetics could decrease early kidney transplant complications 2Health News:Gen-Probe to Webcast Presentation at the 20th Annual Piper Jaffray Health Care Conference 2Health News:New System Improves Distribution of Donated Livers 2Health News:New System Improves Distribution of Donated Livers 3Health News:Melissa Murer Corrigan Receives Prestigious NOCA Leadership Award 2Health News:Melissa Murer Corrigan Receives Prestigious NOCA Leadership Award 3Health News:Citizens Republic Bancorp Selects HealthPlus as Sole Provider of Health Insurance for 2009 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: