Navigation Links
Start of Phase I Study for Intranasal Pandemic Influenza Vaccine deltaFLU
Date:7/8/2008

VIENNA, Austria, July 8 /PRNewswire/ -- Avir Green Hills Biotechnology starts a clinical phase I study with its intranasal vaccine deltaFLU against pandemic influenza. This novel generation of a live-attenuated vaccine based on the deletion of the NS1 gene has shown superior preclinical data. In taking this step, the Viennese biotech company sets yet another milestone in the development of effective and safe vaccines.

Aim of Phase I Study

The randomized, double-blind phase I study of the pandemic vaccine deltaFLU will be run at the Department of Clinical Pharmacology, Medical University of Vienna. The aim of phase I study is to analyze the safety and efficacy of the vaccine in healthy volunteers.

Preclinical Data, Pandemic Vaccine

"Our vaccine lacks the pathogenicity factor NS1. Due to this deletion, the vaccine is likely to show a superior safety profile. We are confident that the pandemic deltaFLU vaccine will be tolerated even at high doses," comments Thomas Muster, founder and CEO/CSO of Avir Green Hills Biotechnology.

Outstanding preclinical data show an excellent immune response even against distantly related pandemic H5 strains (cross-protection). Moreover, a long lasting immune response - an important prerequisite for an effective vaccine - was observed.

"We are very pleased about the success of our vaccine in the preclinical studies. The data are superb and exceed our highest expectations," reports Andrej Egorov, who is Vice President for Research at Avir Green Hills Biotechnology and one of the leading experts in the field of live attenuated influenza vaccines.

The novel influenza vaccine deltaFLU

differs from a conventional influenza vaccine in three major characteristics and in the method of production:

1. Nasal Spray

The vaccine is administered intranasally with a spray device instead of being injected into a muscle. This approach offers the major advantage of stimulating the v
'/>"/>

SOURCE Avir Green Hills Biotechnology Trade AG
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. BN ImmunoTherapeutics Starts Clinical Trials With Prostate Cancer Vaccine
2. InterMune Announces Start of 14-Day Triple Combination Study of ITMN-191 in Patients With Chronic Hepatitis C
3. Impliant Restarts Pivotal Clinical Trial for Patented TOPS(TM) Spine System
4. TriLink Awarded a Phase II Grant for a Second Hot Start PCR Project
5. Starting Flu Vaccination in August Could Help Protect Nearly 11 Million More Children During Scheduled Doctors Visits
6. MedImmune Advances Asthma Program with Start of a Phase 2 Trial in Europe and Australia and First U.S.-Based Clinical Trial for Antibody Targeting IL-13
7. Diamyd(R) Diabetes Vaccine Receives Approval to Start Phase III Trials in Europe
8. VIDEO: Femara(R) helps protect against return of breast cancer even when treatment starts several years after completing tamoxifen therapy
9. Michael J. Fox Foundation Awards Up to $3 Million to Industry Teams to Jumpstart Promising PD Drug Development
10. Pharmion and MethylGene Start Phase 2 Combination Clinical Trial With MGCD0103 and Vidaza(R) in Patients With Relapsed or Refractory Hodgkin Lymphoma or Non-Hodgkin Lymphoma
11. GlaxoSmithKline and Theravance Announce Start of Large Phase 2B ICS and LABA Studies for Asthma in the Horizon Program
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2015)... Levi & Korsinsky announces it has commenced ... ) concerning possible violations of federal securities laws. The ... connection with its study of the drug OHR-102. To ... contact Joseph E. Levi, Esq. either via ... (212) 363-7500, toll-free: (877) 363-5972. Levi & ...
(Date:3/27/2015)... March 27, 2015 /PRNewswire/ - Medicure Inc. (the "Company") ... has approved the grant of an aggregate of 236,070 ... and consultants of the Company pursuant to the Company,s ... to expire on the tenth anniversary of the date ... third anniversary of the date of grant and 50,000 ...
(Date:3/27/2015)... 2015 /CNW Telbec/ - Russell Williams , President ... (Rx&D), welcomes the 2015-2016 Quebec Budget, noting the fiscal ... the biopharmaceutical industry. However, the association is concerned about ... commend the government,s intent to strive for a balanced ... promote Quebec,s economic development is ...
Breaking Medicine Technology:Quebec 2015-2016 Budget: Rx&D welcomes fiscal discipline and biopharma working group, but the decrease in government spending on medicines is questioned 2Quebec 2015-2016 Budget: Rx&D welcomes fiscal discipline and biopharma working group, but the decrease in government spending on medicines is questioned 3
... Calif., March 31, 2011 NewCardio, Inc., (OTC Bulletin ... developer, announced today that the Company has been invited ... performance study at an upcoming conference entitled "Cardiovascular Safety ... Food and Drug Administration (FDA), the Cardiac Safety Research ...
... 31, 2011 The U.S. Department of Energy has ... field of medical technology and innovation for commercializing the ... agency, Dilon and similar entrepreneurs, "build the new industries ... our toughest global challenges." The Dilon 6800® ...
Cached Medicine Technology:NewCardio Invited to Present Latest QTinno Performance Improvements at FDA-Sponsored Conference on Cardiovascular Safety in Drug Development 2NewCardio Invited to Present Latest QTinno Performance Improvements at FDA-Sponsored Conference on Cardiovascular Safety in Drug Development 3NewCardio Invited to Present Latest QTinno Performance Improvements at FDA-Sponsored Conference on Cardiovascular Safety in Drug Development 4NewCardio Invited to Present Latest QTinno Performance Improvements at FDA-Sponsored Conference on Cardiovascular Safety in Drug Development 5NewCardio Invited to Present Latest QTinno Performance Improvements at FDA-Sponsored Conference on Cardiovascular Safety in Drug Development 6U.S. Department of Energy Hails Dilon Diagnostics as a Medical Technology Pioneer and Top National Innovator 2
(Date:3/28/2015)... Mirada, CA (PRWEB) March 28, 2015 ... ear, nose and throat disorders, are now ... is a common issue which is characterized by the ... Affecting 1 in 5 people, tinnitus is a prevalent ... disorder and while it is non-fatal, tinnitus can impede ...
(Date:3/28/2015)... March 28, 2015 ARDX will sponsor the ... 12pm -3pm at the Chesapeake Conference Center in Chesapeake, Virginia. ... an empowering event for women in the Hampton Roads region. ... Stories of Women’s Lives. Women grow stronger through sharing ... other. This year the WWC™ theme is T-talk where ...
(Date:3/28/2015)... LTW Cyber is an innovation hub for ... purpose of addressing the needs of the global market ... opportunities to grow while seeking collaborative opportunities with the ... Ventures in LTW Cyber focus on secure application security, ... vulnerabilities and analyzing open source. As the hub ...
(Date:3/27/2015)... Deer, Alberta (PRWEB) March 27, 2015 In ... until then, prevented her from working, Monica K. arrived at ... in the mending department quiet, defensive and scared. The owners ... Placement & Support Services (EPSS) to offer jobs to ... does take patience and a willingness to begin with the ...
(Date:3/27/2015)... Lewisville, Texas (PRWEB) March 27, 2015 ... at 7am today. The new facility is located 12665 W ... , “As a resident of Summerwood, I look forward to ... here,” said Dr. Sowell, Facility Medical Director of First Choice ... First Choice Emergency Room made a donation to Summer Creek ...
Breaking Medicine News(10 mins):Health News:Healthpointe now Offering Tinnitus Treatments in Clinics throughout Southern California 2Health News:Canadian Cybersecurity Ventures Globalize as a Collective 2Health News:Canadian Cybersecurity Ventures Globalize as a Collective 3Health News:Red Deer Uniforms Shop Celebrates 3rd Year Sewing Hope for the Challenged 2Health News:Red Deer Uniforms Shop Celebrates 3rd Year Sewing Hope for the Challenged 3Health News:First Choice Emergency Room Opens New Facility in Houston, Texas 2
... of Dimes and Kmart--Working Together for Stronger, Healthier,Babies, ... premature birth rises in the U.S., Kmart,s partnership with ... Kmart,s associates and customers,have raised an unprecedented $71 million ... This year, Kmart,s 2008 March for Babies,campaign topped the ...
... Efforts Oppose $6.5 Million Funding Cut to State,s ... The Arkansas,Health Care Association and the American Health ... and Mark Pryor (D) and,Representatives Marion Berry (D-1st), ... (D-4th) for helping lead efforts in the U.S. ...
... the 1 in 8 Hispanics with type 2 disease , , ... of the most serious health issues facing Hispanics in the ... diabetes has been released. , The Agency for Healthcare Research ... 2 , a consumer guide aimed at the estimated one ...
... From Various Pro Teams During Each Tour ... Stage, LAKE SUCCESS, N.Y., July 2 , WHO: ... assessment technology, WHAT: Micro-site ... various pro cyclists during every stage of the Tour de France. ...
... Inc., the,highly respected developer and manufacturer of proprietary ... Stable Liquid L-Ascorbic Acid,(Vitamin C), has terminated the ... right to exclusively market the proprietary,product formulas of ... IS Clinical termination was triggered by that company,s,introduction ...
... rises in caesarean section rates, according to a paper ... The findings come from an analysis of a large ... Professor Gordon Smith, at the University,s Department of Obstetrics ... 500,000 entries collected by the Scottish Morbidity Record between ...
Cached Medicine News:Health News:4 Million Babies Born Each Year in United States; $8 Million That Shows You Care About All of Them! 2Health News:State, National Long Term Care Community Applauds Arkansas Leaders in U.S. Senate and U.S. House for Helping Lead Effort to Block $770 Million Bush Medicare Cuts 2Health News:State, National Long Term Care Community Applauds Arkansas Leaders in U.S. Senate and U.S. House for Helping Lead Effort to Block $770 Million Bush Medicare Cuts 3Health News:New Spanish Consumer Guide Compares Diabetes Meds 2Health News:Polar to Feature Live Tour de France Race Data 2Health News:Termination of IS Clinical From Distributing PhytoCeuticals Formulas 2Health News:Major rise in Caesarean sections linked to impaired womb function with age 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: