Navigation Links
Star Scientific Reports Publication of First Peer-Reviewed Article on the Effects of Anatabine in an Animal Model of Multiple Sclerosis
Date:1/31/2013

e array of inflammatory genes including cytokines, suggesting a mechanism by which anatabine antagonizes pro-inflammatory cytokine production.

In addition, the researchers found that anatabine reduced the infiltration of inflammatory cells in the brain and significantly prevented demyelination in the spinal cord of EAE mice. In humans, demyelination in the spinal cord is associated with muscle weakness and paralysis in MS. Therefore, the researchers concluded that the "data suggest that anatabine may be effective in the treatment of MS."

Dr. Michael Mullan , President and CEO of the Roskamp Institute, commented, "The most remarkable results were the clear inhibition of brain inflammation and the degeneration of the spinal cord by anatabine and the accompanying inhibition of the severe paralysis that usually accompanied the model."

Dr. Daniel Paris , the primary author of the article and Head of Research and Development at the Roskamp Institute, added, "The oral administration of anatabine potently reduced the neurological deficits and abrogated the pathological lesions in the spinal cord that are responsible for the development of paralysis in this mouse model of multiple sclerosis (MS). In addition our work also explains the beneficial activity of anatabine in this MS model by showing that this compound prevents the activation of key molecules that orchestrate the propagation of inflammation in the central nervous system and the periphery."

The full title of the study is, "Amelioration of Experimental Autoimmune Encephalomyelitis by Anatabine," and can be viewed here: http://dx.plos.org/10.1371/journal.pone.0055392. This study builds upon earlier research conducted by the Roskamp Institute, which showed that the natural alkaloid anatabine displays anti-inflammatory properties and readily crosses the blood brai
'/>"/>

SOURCE Star Scientific, Inc.
Copyright©2012 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4

Related medicine technology :

1. Boston Scientific Announces CE Mark and European Launch of Emerge™ PTCA Dilatation Catheter
2. Shire to Present Scientific Data Across Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting May 5-9
3. Boston Scientific and Philips Healthcare Announce Collaboration to Enhance Imaging Equipment Offering
4. Boston Scientific Announces Positive Data From Lotus™ Transcatheter Aortic Valve Trial
5. One-Year EVOLVE Trial Clinical Results Confirm Comparable Safety And Effectiveness Data Of The Boston Scientific SYNERGY™ Stent Versus PROMUS Element™ Platinum Chromium Stent
6. Generex Announces New Members of Antigen Express Scientific Advisory Board for the AE37 Breast Cancer Vaccine
7. Boston Scientific Announces FDA Approval and U.S. Launch of EPIC™ Vascular Stent
8. Generex Augments Antigen Express Scientific Advisory Board
9. Receptos to Deliver Scientific Presentation at Digestive Disease Week 2012 about the Therapeutic Role of RPC1063 in Inflammatory Bowel Disease
10. Boston Scientific Endoscopy Presents Promising Clinical Data During Digestive Disease Week ®
11. Lilly Diabetes Presents Phase II Blood Pressure and Heart Rate Data on Investigational GLP-1 Analog Candidate, Dulaglutide, in Patients with Type 2 Diabetes at the 27th American Society of Hypertension Scientific Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... 2013   Direct to implant, or "one ... appropriate option for many women with BRCA (BReast ... breast cancer risk, or with breast cancer. Traditionally, ... a second surgery to insert permanent implants, but ... as mastectomy can be a medically and cosmetically ...
(Date:5/23/2013)...  BioElectronics Corporation (OTC Pink: BIEL), the maker of ... FDA panel meeting for non-thermal shortwave diathermy: ... Therapy Meeting was held on May 21, 2013 in ... of the meeting was very narrow, in that the ... the application of non-thermal shortwave diathermy for the treatment ...
(Date:5/23/2013)... SAN MATEO, Calif. , May 23, 2013 ... selected the company to enable data discovery on ... business users the self-service tools they need to ... make meaningful decisions. A Fortune 19 ... largest healthcare services companies. It provides pharmaceuticals and ...
Breaking Medicine Technology:Direct to Implant ("One Step") Mastectomy Breast Reconstruction Reduces Number of Surgeries and Time to Final Cosmetic Results 2Direct to Implant ("One Step") Mastectomy Breast Reconstruction Reduces Number of Surgeries and Time to Final Cosmetic Results 3BioElectronics and Pulsed Shortwave Therapy Make Progress 2Cardinal Health Selects Datameer for Healthcare Data Discovery 2
... Calif., Aug. 15, 2011 NewCardio, Inc., (OTC BB: NWCI) ... the second quarter ended June 30, 2011. More details on ... on Form 10-Q, filed today with the Securities and Exchange ... selected by a top 5 global pharmaceutical company for two ...
... Medical (the Company), a leading provider of quality home ... throughout the United States announced today the appointment of ... President and Chief Financial Officer.  Steve Saft, CCS Medical,s ... transition period. President and Chief Executive Officer ...
Cached Medicine Technology:NewCardio Announces Financial Results for Its 2011 Second Quarter 2NewCardio Announces Financial Results for Its 2011 Second Quarter 3NewCardio Announces Financial Results for Its 2011 Second Quarter 4NewCardio Announces Financial Results for Its 2011 Second Quarter 5NewCardio Announces Financial Results for Its 2011 Second Quarter 6NewCardio Announces Financial Results for Its 2011 Second Quarter 7NewCardio Announces Financial Results for Its 2011 Second Quarter 8CCS Medical Appoints Michael A. Sicuro as Executive Vice President and Chief Financial Officer 2
(Date:5/23/2013)... (PRWEB) May 23, 2013 Platinum ... Missouri, to sales team leader. Satterlee started her Platinum ... her career to lead a team of sales representatives ... policies, primarily to farmers and residents of rural communities. ... sales representatives whose job it is help farmers prepare ...
(Date:5/23/2013)... City, Utah (PRWEB) May 23, 2013 ... PhD, R.D., published an article today on Tatalou.com offering ... illness-free vacation. , The article, titled “ How to ... it’s important to carry hand sanitizer, when it’s safe ... watch out for seafood, the importance of staying hydrated ...
(Date:5/23/2013)... Jim Fitzpatrick just did it again. ... yet another outside-of-the-box approach to reaching the retail automotive ... daily newscasts to the retail automotive industry, blending the ... broadcast news format. , CBTNews.com is an innovative ... Bridget Everett and Russell Brown host the show with ...
(Date:5/23/2013)... To better serve the architecture ... pleased to announce the release of its new ... space division products. Provided by Koroseal, a leader ... patterns and colors represent a sophisticated response to ... a team of Koroseal experts, Modernfold reviewed hundreds ...
(Date:5/23/2013)... known about the human potential to cultivate compassion ... suffering in a way that motivates altruistic behavior. ... for Investigating Healthy Minds at the Waisman Center of ... trained to be more compassionate. The report, recently published ... the first to investigate whether training adults in compassion ...
Breaking Medicine News(10 mins):Health News:Platinum Supplemental Insurance Promotes Mary Satterlee to Sales Team Leader 2Health News:How to Stay Healthy While Traveling 2Health News:Fitzpatrick Advertising Founder Brings Auto Industry into Focus with CBT News 2Health News:Modernfold Debuts New Colors and Patterns for Space Division Products 2Health News:Study shows people can be trained to be more compassionate 2Health News:Study shows people can be trained to be more compassionate 3Health News:Study shows people can be trained to be more compassionate 4
... disease has affected the ecological balance existing between native and ... the number of devils has sharply reduced. David Pemberton a ... devil population in the Mt William National Park. The ... carcasses lying around the area. Wedge-tailed eagles are feeding on ...
... the Scots are facing a severe backlog in trying to ... ,They fear that there would not be enough practitioners ... the NHS is forcing the dentists out. According to the ... is found that there are 2367 NHS High Street dentists ...
... Dr Allan Pantuck it was found that pomegranate juice has ... is the most common cancer affecting men in the UK. ... about 10,000 die from the disease. Prostate-specific antigen (PSA) ... cancer. But study shows that consumption of a glass of ...
... admissions running at double the number of what they were ... time high//.,Deaths due to alcoholic liver disease had risen by ... revealed. , Office for National Statistics figures compiled ... with alcoholic liver disease last year, compared to 14,400 admissions ...
... several older brothers increases the chances of a man being ... idea of a biological basis for sexual orientation. ... Canada said, "It's likely to be a prenatal effect. This ... basis for homosexuality." ,S Marc Breedlove of Michigan ...
... have been reported by residents living near the former ... following the massive fire which ripped// through this industrial ... common health problems such as eczema, asthma, psoriasis and ... no evidence of a link between the illnesses and ...
Cached Medicine News:Health News:Alcohol-Related Illnesses On The Rise 2Health News:No Clue to Cause of Mystery Illnesses 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: