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Star Scientific, Inc. Refutes Story Published on TheStreet.com
Date:1/28/2013

nce backing that anatabine reduces inflammation similarly is completely false.  Since 2011, Rock Creek Pharmaceuticals and researchers at the Roskamp Institute have completed and reported on a number of studies designed to assess the ability of the Company's anatabine compound to lower chronic inflammation in a variety of pre-clinical (non-human) and clinical (human) settings. One study conducted by the Roskamp Institute and reported in The Journal of European Pharmacology in 2011 showed that anatabine lowered levels of amyloid production both in the test tube and when administered to mice vulnerable to accumulation of amyloid which, at excessive levels damages brain tissue.  A second manuscript written by the same researchers and published online in The Journal of European Pharmacology in 2012 and in manuscript form in January 2013 further characterized the anti-inflammatory effects of anatabine in several types of animal tissues, in human cells, and in human whole blood. The Roskamp Institute also presented results of pre-clinical studies of anatabine in mouse models of multiple sclerosis, traumatic brain injury, and Alzheimer's disease at the Neuroscience 2012 conference held in New Orleans in October 2012.

In January 2012, Rock Creek Pharmaceuticals reported research on the first clinical trial demonstrating that Anatabloc® lowers chronic inflammation measured by CRP levels in the blood. The reported results were obtained in connection with an in-house study undertaken by Rock Creek that involved a group of smokers who had been using Anatabloc® on an extended basis.  In October 2012, Rock Creek reported on an interim look at the CRP results in a study sponsored by the Roskamp Institute and designed to assess the safety, tolerability, dosing, and biological effects of anatabine citrate.  Currently, a clinical study of individuals with mild to moderate Alzheimer's d
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SOURCE Star Scientific, Inc.
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